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Timothy J Nott
Timothy J Nott
Verifierad e-postadress på kcl.ac.uk
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Phase transition of a disordered nuage protein generates environmentally responsive membraneless organelles
TJ Nott, E Petsalaki, P Farber, D Jervis, E Fussner, A Plochowietz, ...
Molecular cell 57 (5), 936-947, 2015
17732015
Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation
JP Brady, PJ Farber, A Sekhar, YH Lin, R Huang, A Bah, TJ Nott, ...
Proceedings of the National Academy of Sciences 114 (39), E8194-E8203, 2017
4772017
Membraneless organelles can melt nucleic acid duplexes and act as biomolecular filters
TJ Nott, TD Craggs, AJ Baldwin
Nature chemistry 8 (6), 569-575, 2016
3562016
Deciphering arginine methylation: Tudor tells the tale
C Chen, TJ Nott, J Jin, T Pawson
Nature reviews Molecular cell biology 12 (10), 629-642, 2011
3482011
Structure and regulation of the human Nek2 centrosomal kinase
P Rellos, FJ Ivins, JE Baxter, A Pike, TJ Nott, DM Parkinson, S Das, ...
Journal of Biological Chemistry 282 (9), 6833-6842, 2007
1502007
Effective inhibitors of the essential kinase PknB and their potential as anti-mycobacterial agents
KEA Lougheed, SA Osborne, B Saxty, D Whalley, T Chapman, N Bouloc, ...
Tuberculosis 91 (4), 277-286, 2011
1012011
An intramolecular switch regulates phosphoindependent FHA domain interactions in Mycobacterium tuberculosis
TJ Nott, G Kelly, L Stach, J Li, S Westcott, D Patel, DM Hunt, S Howell, ...
Science signaling 2 (63), ra12-ra12, 2009
962009
Structural and functional analysis of phosphothreonine-dependent FHA domain interactions
S Pennell, S Westcott, M Ortiz-Lombardía, D Patel, J Li, TJ Nott, ...
Structure 18 (12), 1587-1595, 2010
612010
Versatility in phospho-dependent molecular recognition of the XRCC1 and XRCC4 DNA-damage scaffolds by aprataxin-family FHA domains
AL Cherry, TJ Nott, G Kelly, SL Rulten, KW Caldecott, SJ Smerdon
DNA repair 35, 116-125, 2015
312015
Ion binding with charge inversion combined with screening modulates DEAD box helicase phase transitions
MD Crabtree, J Holland, AS Pillai, PS Kompella, L Babl, NN Turner, ...
Cell Reports 42 (11), 2023
172023
Repulsive electrostatic interactions modulate dense and dilute phase properties of biomolecular condensates
MD Crabtree, J Holland, P Kompella, L Babl, N Turner, AJ Baldwin, ...
Biorxiv, 2020.10. 29.357863, 2020
122020
Surface tension measurement and calculation of model biomolecular condensates
J Holland, AA Castrejón-Pita, R Tuinier, DGAL Aarts, TJ Nott
Soft Matter 19 (45), 8706-8716, 2023
62023
In vitro transition temperature measurement of phase-separating proteins by microscopy
J Holland, MD Crabtree, TJ Nott
Intrinsically Disordered Proteins: Methods and Protocols, 703-714, 2020
42020
Biomolecule separation and modification
A Baldwin, T Nott
US Patent App. 15/769,597, 2018
32018
Phase Separation of Disordered Protein in the Formation of Membrane-Less Organelles
TJ Nott, P Farber, E Petsalakis, D Jervis, AJ Baldwin, JD Forman-Kay
Biophysical Journal 106 (2), 35a, 2014
12014
UnidecNMR: automatic peak detection for NMR spectra in 1-4 dimensions
C Buchanan, G Karunanithy, O Tkachenko, M Barber, MT Marty, TJ Nott, ...
Nature Communications 16 (1), 449, 2025
2025
Kinetic Resolution of Epimeric Proteins Enables Stereoselective Chemical Mutagenesis
G Ablat, N Lawton, R Alam, BA Haynes, S Hossain, T Hicks, SL Evans, ...
Journal of the American Chemical Society 146 (32), 22622-22628, 2024
2024
Alternative solvent for biology
T Nott, T Craggs, P Farber, J Forman-Kay, A Baldwin
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017
2017
Structural and functional analysis of a phospho-dependent molecular switch: Rv1827 from Mycobacterium tuberculosis
TJ Nott
UCL (University College London), 2009
2009
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Artiklar 1–19