The Notch signalling system: recent insights into the complexity of a conserved pathway KG Guruharsha, MW Kankel, S Artavanis-Tsakonas Nature Reviews Genetics 13 (9), 654-666, 2012 | 877 | 2012 |
Context-dependent and disease-specific diversity in protein interactions within stress granules S Markmiller, S Soltanieh, KL Server, R Mak, W Jin, MY Fang, EC Luo, ... Cell 172 (3), 590-604. e13, 2018 | 874 | 2018 |
Arabidopsis MET1 Cytosine Methyltransferase Mutants MW Kankel, DE Ramsey, TL Stokes, SK Flowers, JR Haag, JA Jeddeloh, ... Genetics 163 (3), 1109-1122, 2003 | 698 | 2003 |
Crossing paths with Notch in the hyper-network GD Hurlbut, MW Kankel, RJ Lake, S Artavanis-Tsakonas Current opinion in cell biology 19 (2), 166-175, 2007 | 282 | 2007 |
Modeling spinal muscular atrophy in Drosophila HCH Chang, DN Dimlich, T Yokokura, A Mukherjee, MW Kankel, A Sen, ... PloS one 3 (9), e3209, 2008 | 220 | 2008 |
Antibody therapy targeting RAN proteins rescues C9 ALS/FTD phenotypes in C9orf72 mouse model L Nguyen, F Montrasio, A Pattamatta, SK Tusi, O Bardhi, KD Meyer, ... Neuron 105 (4), 645-662. e11, 2020 | 101 | 2020 |
PINK1/Parkin influences cell cycle by sequestering TBK1 at damaged mitochondria, inhibiting mitosis SA Sarraf, DP Sideris, N Giagtzoglou, L Ni, MW Kankel, A Sen, ... Cell reports 29 (1), 225-235. e5, 2019 | 88 | 2019 |
Exploring the genetics and non-cell autonomous mechanisms underlying ALS/FTLD H Chen, MW Kankel, SC Su, SWS Han, D Ofengeim Cell Death & Differentiation 25 (4), 648-662, 2018 | 82 | 2018 |
Investigating the genetic circuitry of mastermind in Drosophila, a notch signal effector MW Kankel, GD Hurlbut, G Upadhyay, V Yajnik, B Yedvobnick, ... Genetics 177 (4), 2493-2505, 2007 | 81 | 2007 |
Modeling spinal muscular atrophy in Drosophila links Smn to FGF signaling A Sen, T Yokokura, MW Kankel, DN Dimlich, J Manent, S Sanyal, ... Journal of Cell Biology 192 (3), 481-495, 2011 | 65 | 2011 |
Nodal points and complexity of Notch-Ras signal integration GD Hurlbut, MW Kankel, S Artavanis-Tsakonas Proceedings of the National Academy of Sciences 106 (7), 2218-2223, 2009 | 51 | 2009 |
Regulation of Protein Quality Control by UBE4B and LSD1 through p53-Mediated Transcription G Periz, J Lu, T Zhang, MW Kankel, M Jablonski, Angela, R Kalb, ... PLoS Biology 13 (4), 29, 2015 | 45 | 2015 |
Genetic circuitry of Survival motor neuron, the gene underlying spinal muscular atrophy A Sen, DN Dimlich, KG Guruharsha, MW Kankel, K Hori, T Yokokura, ... Proceedings of the National Academy of Sciences 110 (26), E2371-E2380, 2013 | 43 | 2013 |
A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation Y Sonobe, J Aburas, G Krishnan, AC Fleming, G Ghadge, P Islam, ... Nature communications 12 (1), 6025, 2021 | 38 | 2021 |
CRISPR deletion of the C9ORF72 promoter in ALS/FTD patient motor neurons abolishes production of dipeptide repeat proteins and rescues neurodegeneration G Krishnan, Y Zhang, Y Gu, MW Kankel, FB Gao, S Almeida Acta neuropathologica 140, 81-84, 2020 | 37 | 2020 |
Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD G Krishnan, D Raitcheva, D Bartlett, M Prudencio, DM McKenna-Yasek, ... Nature communications 13 (1), 2799, 2022 | 36 | 2022 |
Production of poly(GA) in C9ORF72 patient motor neurons derived from induced pluripotent stem cells S Almeida, G Krishnan, M Rushe, Y Gu, MW Kankel, FB Gao Acta Neuropathologica 138, 1099-1101, 2019 | 33 | 2019 |
Amyotrophic Lateral Sclerosis Modifiers in Drosophila Reveal the Phospholipase D Pathway as a Potential Therapeutic Target MW Kankel, A Sen, L Lu, M Theodorou, DN Dimlich, A McCampbell, ... Genetics 215 (3), 747-766, 2020 | 28 | 2020 |
A screen for genes that interact with the Drosophila pair-rule segmentation gene fushi tarazu MW Kankel, DM Duncan, I Duncan Genetics 168 (1), 161-180, 2004 | 19 | 2004 |
In vivo genome editing using novel AAV-PHP variants rescues motor function deficits and extends survival in a SOD1-ALS mouse model YA Chen, MW Kankel, S Hana, SK Lau, MI Zavodszky, O McKissick, ... Gene Therapy 30 (5), 443-454, 2023 | 14 | 2023 |