| Spider-venom peptides that target voltage-gated sodium channels: pharmacological tools and potential therapeutic leads JK Klint, S Senff, DB Rupasinghe, SY Er, V Herzig, GM Nicholson, ... Toxicon 60 (4), 478-491, 2012 | 257 | 2012 |
| Discovery of a selective NaV1. 7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models S Yang, Y Xiao, D Kang, J Liu, Y Li, EAB Undheim, JK Klint, M Rong, ... Proceedings of the National Academy of Sciences 110 (43), 17534-17539, 2013 | 221 | 2013 |
| From foe to friend: using animal toxins to investigate ion channel function J Kalia, M Milescu, J Salvatierra, J Wagner, JK Klint, GF King, BM Olivera, ... Journal of molecular biology 427 (1), 158-175, 2015 | 184 | 2015 |
| Production of recombinant disulfide-rich venom peptides for structural and functional analysis via expression in the periplasm of E. coli JK Klint, S Senff, NJ Saez, R Seshadri, HY Lau, NS Bende, EAB Undheim, ... PloS one 8 (5), e63865, 2013 | 175 | 2013 |
| Seven novel modulators of the analgesic target NaV1.7 uncovered using a high‐throughput venom‐based discovery approach JK Klint, JJ Smith, I Vetter, DB Rupasinghe, SY Er, S Senff, V Herzig, ... British journal of pharmacology 172 (10), 2445-2458, 2015 | 91 | 2015 |
| Discovery and Characterization of the Potent and Selective P2X4 Inhibitor N-[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and … S Werner, S Mesch, RC Hillig, A Ter Laak, J Klint, I Neagoe, ... Journal of Medicinal Chemistry 62 (24), 11194-11217, 2019 | 49 | 2019 |
| Rational engineering defines a molecular switch that is essential for activity of spider-venom peptides against the analgesics target NaV1. 7 JK Klint, YKY Chin, M Mobli Molecular Pharmacology 88 (6), 1002-1010, 2015 | 34 | 2015 |
| Isolation, synthesis and characterization of ω-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type Cav channels JK Klint, G Berecki, T Durek, M Mobli, O Knapp, GF King, DJ Adams, ... Biochemical Pharmacology 89 (2), 276-286, 2014 | 25 | 2014 |
| Fluorescence labeling of a NaV1.7-targeted peptide for near-infrared nerve visualization J Gonzales, G Pirovano, CY Chow, PD de Souza Franca, LM Carter, ... EJNMMI research 10, 1-8, 2020 | 19 | 2020 |
| Apo and ligand-bound high resolution Cryo-EM structures of the human Kv3. 1 channel reveal a novel binding site for positive modulators M Botte, S Huber, D Bucher, JK Klint, D Rodríguez, L Tagmose, M Chami, ... PNAS nexus 1 (3), pgac083, 2022 | 11 | 2022 |
| Apo and ligand-bound high resolution Cryo-EM structures of the human Kv3. 1 reveal a novel binding site for positive modulators M Botte, S Huber, D Bucher, JK Klint, D Rodríguez, L Tagmose, M Chami, ... bioRxiv, 2021.07. 13.452180, 2021 | 2 | 2021 |
| 31. Spider-venom Peptides that Target the Human NaV1. 7 channel: Potential Analgesics for the Treatment of Chronic Pain J Klint, R Anangi, M Mobli, O Knapp, DJ Adams, GF King Toxicon 60 (2), 110-111, 2012 | 2 | 2012 |
| So potent wie Morphin S Yang, Y Xiao, D Kang, J Liu, Y Li, EA Undheim, JK Klint, M Rong, R Lai, ... Journal Club Schmerzmedizin 3 (01), 46-46, 2014 | | 2014 |
| Characterisation of spider-venom peptides that target voltage-gated sodium channels: pharmacological tools and potential therapeutic leads for the treatment of chronic pain J Klint | | 2014 |
| Production of Recombinant Disulfide-Rich Venom Peptides for Structural and Functional JK Klint, S Senff, NJ Saez, R Seshadri, HY Lau | | 2013 |
Glenn F. KingProfessor, Institute for Molecular BioscienceVerifierad e-postadress på imb.uq.edu.au