Följ
ZHANG YING
ZHANG YING
Cancer Science Institute (CSI)-National University of Singapore
Verifierad e-postadress på u.nus.edu
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H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions
Y Cai, Y Zhang, YP Loh, JQ Tng, MC Lim, Z Cao, A Raju, ...
Nature communications 12 (1), 719, 2021
2692021
TP63, SOX2, and KLF5 establish a core regulatory circuitry that controls epigenetic and transcription patterns in esophageal squamous cell carcinoma cell lines
YY Jiang, Y Jiang, CQ Li, Y Zhang, P Dakle, H Kaur, JW Deng, RYT Lin, ...
Gastroenterology 159 (4), 1311-1327. e19, 2020
1332020
Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer
LY Li, Q Yang, YY Jiang, W Yang, Y Jiang, X Li, M Hazawa, B Zhou, ...
Nature communications 12 (1), 4362, 2021
882021
Chromatin interaction neural network (ChINN): a machine learning-based method for predicting chromatin interactions from DNA sequences
F Cao, Y Zhang, Y Cai, S Animesh, Y Zhang, SC Akincilar, YP Loh, X Li, ...
Genome biology 22, 1-25, 2021
452021
Super-enhancers, phase-separated condensates, and 3D genome organization in cancer
SC Tang, U Vijayakumar, Y Zhang, MJ Fullwood
Cancers 14 (12), 2866, 2022
302022
Long-distance repression by human silencers: chromatin interactions and phase separation in silencers
Y Zhang, YX See, V Tergaonkar, MJ Fullwood
Cells 11 (9), 1560, 2022
212022
A multimodal atlas of hepatocellular carcinoma reveals convergent evolutionary paths and ‘bad apple’effect on clinical trajectory
J Chen, NA Kaya, Y Zhang, RI Kendarsari, K Sekar, SL Chong, ...
Journal of Hepatology 81 (4), 667-678, 2024
52024
Super-silencers regulated by chromatin interactions control apoptotic genes
Y Zhang, K Chen, Y Cai, A Nambu, YX See, C Fu, A Raju, M Lakshmanan, ...
bioRxiv, 2022.01. 17.476559, 2022
32022
Super-silencer perturbation by EZH2 and REST inhibition leads to large loss of chromatin interactions and reduction in cancer growth
Y Zhang, K Chen, SC Tang, Y Cai, A Nambu, YX See, C Fu, A Raju, ...
Nature Structural & Molecular Biology 32 (1), 137-149, 2025
2025
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