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Sailajah Gukathasan
Sailajah Gukathasan
Post Doctoral Research Fellow
Verifierad e-postadress på bc.edu
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Next generation gold drugs and probes: chemistry and biomedical applications
RT Mertens, S Gukathasan, AS Arojojoye, C Olelewe, SG Awuah
Chemical Reviews 123 (10), 6612-6667, 2023
722023
Cyclometalated Gold (III) complexes bearing DACH ligands
S Gukathasan, S Parkin, SG Awuah
Inorganic chemistry 58 (14), 9326-9340, 2019
472019
Tuning cyclometalated gold (III) for cysteine arylation and ligand-directed bioconjugation
S Gukathasan, S Parkin, EP Black, SG Awuah
Inorganic chemistry 60 (19), 14582-14593, 2021
242021
Gold (III)-P-chirogenic complex induces mitochondrial dysfunction in triple-negative breast cancer
C Olelewe, JH Kim, S Ofori, RT Mertens, S Gukathasan, SG Awuah
Iscience 25 (5), 2022
172022
Gold‐Based Pharmacophore Inhibits Intracellular MYC Protein
S Ofori, S Gukathasan, SG Awuah
Chemistry–A European Journal 27 (12), 4168-4175, 2021
122021
Serum-Stable Gold (III) Bisphosphine Complex Induces Mild Mitochondrial Uncoupling and In Vivo Antitumor Potency in Triple Negative Breast Cancer
AS Arojojoye, C Olelewe, S Gukathasan, JH Kim, H Vekaria, S Parkin, ...
Journal of Medicinal Chemistry 66 (12), 7868-7879, 2023
92023
Synthetic Strategies for the Preparation of Gold-based Anticancer Agents
SGA Sailajah Gukathasan
Encyclopedia of Inorganic and Bioinorganic Chemistry, 2022
4*2022
A Conformationally Restricted Gold (III) Complex Elicits Antiproliferative Activity in Cancer Cells
S Gukathasan, OA Obisesan, S Saryazdi, L Ratliff, S Parkin, ...
Inorganic Chemistry 62 (32), 13118-13129, 2023
22023
Metal-Mediated Ligand Affinity Chemistry (MLAC)
SGA Sailajah Gukathasan
Therapeutic Proteins -Methods in Molecular Biology 2720, 85-97, 2023
2023
Covalent modification of native c-MYC protein by Au(I) pharmacophore
SA Sailajah Gukathasan, Samuel Ofori, Oluwatosin Obisesan
ACS Spring 2022, 2022
2022
Develop gold mediated covalent inhibitor for KRAS(G12C)
S Gukathasan, E Black, SG Awuah
261st ACS National Meeting, 2021
2021
The exploration and analysis of alternative orienting media for use in residual dipolar coupling NMR
D Gardner, W Graham, S Gukathasan, W Carroll
Proceedings of Student Research and Creative Inquiry Day 2, 2018
2018
Conformational analysis of Thiosemicarbazone ligands and their metal complexes in solution using residual dipolar couplings (RDCs)
S Gukathasan, W Carroll
68th Southeastern Regional Meeting of the American Chemical Society …, 2016
2016
Determining the 3D structure of metal ligand complexes in solution using nuclear magnetic resonance (NMR) spectroscopy via residual dipolar couplings (RDCs)
S Gukathasan, W Carroll
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016
2016
Determining the 3D structure of ligands and their metal ligand complexes in solution by nuclear magnetic resonance (NMR) spectroscopy using Residual Dipolar Couplings (RDCs)
S Gukathasan
Tennessee Technological University, 2016
2016
Determining the structure of metal ligand complexes in solution by nuclear magnetic resonance (NMR) spectroscopy using residual dipolar couplings (RDCs)
S By Gukathasan, W Carroll
67th Southeast/71st Southwest Joint Regional Meeting of the American …, 2015
2015
DEVELOPMENTS IN GOLD (III) SCAFFOLDS FOR PROTEIN BIOCONJUGATION AND ENHANCED ANTICANCER ACTIVITY
S Gukathasan
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Artiklar 1–17