| Genome-editing technologies: principles and applications T Gaj, SJ Sirk, S Shui, J Liu Cold Spring Harbor Perspectives in Biology 8 (12), a023754, 2016 | 454 | 2016 |
| Targeted gene knockout by direct delivery of zinc-finger nuclease proteins T Gaj, J Guo, Y Kato, SJ Sirk, CF Barbas Nature Methods 9 (8), 805-807, 2012 | 429 | 2012 |
| Cell-penetrating peptide-mediated delivery of TALEN proteins via bioconjugation for genome engineering J Liu, T Gaj, JT Patterson, SJ Sirk, CF Barbas III PLOS ONE 9 (1), e85755, 2014 | 212 | 2014 |
| A metabolic pathway for activation of dietary glucosinolates by a human gut symbiont CS Liou, SJ Sirk, CAC Diaz, AP Klein, CR Fischer, SK Higginbottom, ... Cell 180 (4), 717-728. e19, 2020 | 123 | 2020 |
| Expanding the scope of site‐specific recombinases for genetic and metabolic engineering T Gaj, SJ Sirk, CF Barbas III Biotechnology and Bioengineering 111 (1), 1-15, 2014 | 88 | 2014 |
| Measurement of aqueous glucose in a model anterior chamber using Raman spectroscopy JL Lambert, JM Morookian, SJ Sirk, MS Borchert Journal of Raman Spectroscopy 33 (7), 524-529, 2002 | 81 | 2002 |
| A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells T Gaj, AC Mercer, SJ Sirk, HL Smith, CF Barbas III Nucleic Acids Research 41 (6), 3937-3946, 2013 | 78 | 2013 |
| Protein delivery using Cys2–His2 zinc-finger domains T Gaj, J Liu, KE Anderson, SJ Sirk, CF Barbas III ACS Chemical Biology 9 (8), 1662-1667, 2014 | 76 | 2014 |
| ImmunoPET imaging of B-cell lymphoma using 124I-anti-CD20 scFv dimers (diabodies) T Olafsen, SJ Sirk, DJ Betting, VE Kenanova, KB Bauer, W Ladno, ... Protein Engineering, Design & Selection 23 (4), 243-249, 2010 | 76 | 2010 |
| Cys-diabody quantum dot conjugates (immunoQdots) for cancer marker detection B Barat, SJ Sirk, KE McCabe, J Li, EJ Lepin, R Remenyi, AL Koh, ... Bioconjugate Chemistry 20 (8), 1474-1481, 2009 | 76 | 2009 |
| Regulation of endogenous human gene expression by ligand-inducible TALE transcription factors AC Mercer, T Gaj, SJ Sirk, BM Lamb, CF Barbas III ACS Synthetic Biology 3 (10), 723-730, 2014 | 74 | 2014 |
| ImmunoPET using engineered antibody fragments: fluorine-18 labeled diabodies for same-day imaging T Olafsen, SJ Sirk, S Olma, CKF Shen, AM Wu Tumor Biology 33, 669-677, 2012 | 72 | 2012 |
| Site-specific, thiol-mediated conjugation of fluorescent probes to cysteine-modified diabodies targeting CD20 or HER2 SJ Sirk, T Olafsen, B Barat, KB Bauer, AM Wu Bioconjugate Chemistry 19 (12), 2527-2534, 2008 | 66 | 2008 |
| Microfluidic-based 18F-labeling of biomolecules for immuno-positron emission tomography K Liu, EJ Lepin, MW Wang, F Guo, WY Lin, YC Chen, SJ Sirk, S Olma, ... Molecular Imaging 10 (3), 7290.2010.00043, 2011 | 62 | 2011 |
| Enhancing the specificity of recombinase-mediated genome engineering through dimer interface redesign T Gaj, SJ Sirk, RD Tingle, AC Mercer, MC Wallen, CF Barbas III Journal of the American Chemical Society 136 (13), 5047-5056, 2014 | 36 | 2014 |
| Expanding the zinc-finger recombinase repertoire: directed evolution and mutational analysis of serine recombinase specificity determinants SJ Sirk, T Gaj, A Jonsson, AC Mercer, CF Barbas III Nucleic Acids Research 42 (7), 4755-4766, 2014 | 32 | 2014 |
| Antibody conjugation approach enhances breadth and potency of neutralization of anti-HIV-1 antibodies and CD4-IgG J Gavrilyuk, H Ban, H Uehara, SJ Sirk, K Saye-Francisco, A Cuevas, ... Journal of Virology 87 (9), 4985-4993, 2013 | 26 | 2013 |
| Measurement of Amphotericin B concentration by Resonant Raman Spectroscopy–a novel technique that may be useful for non-invasive monitoring WV La Via, JL Lambert, MJ Pelletier, J Michael Morookian, SJ Sirk, ... Medical Mycology 44 (2), 169-174, 2006 | 24 | 2006 |
| Living therapeutics: the next frontier of precision medicine VW Kelly, BK Liang, SJ Sirk ACS Synthetic Biology 9 (12), 3184-3201, 2020 | 20 | 2020 |
| Genome-editing technologies: principles and applications. Cold Spring Harb Perspect Biol 8: a023754 T Gaj, SJ Sirk, SL Shui, J Liu | 19 | 2016 |
Thomas GajAssistant Professor of Bioengineering, University of Illinois Urbana-ChampaignVerifierad e-postadress på illinois.edu
