| In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration K Suzuki, Y Tsunekawa, R Hernandez-Benitez, J Wu, J Zhu, EJ Kim, ... Nature 540 (7631), 144-149, 2016 | 1285 | 2016 |
| NF-κB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK GH Liu, J Qu, X Shen Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (5), 713-727, 2008 | 773 | 2008 |
| Database resources of the national genomics data center, China national center for bioinformation in 2022 Nucleic Acids Research 50 (D1), D27-D38, 2022 | 711 | 2022 |
| Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome GH Liu, BZ Barkho, S Ruiz, D Diep, J Qu, SL Yang, AD Panopoulos, ... Nature 472 (7342), 221-225, 2011 | 647 | 2011 |
| A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging W Zhang, J Li, K Suzuki, J Qu, P Wang, J Zhou, X Liu, R Ren, X Xu, ... Science 348 (6239), 1160-1163, 2015 | 567 | 2015 |
| Repression of the antioxidant NRF2 pathway in premature aging N Kubben, W Zhang, L Wang, TC Voss, J Yang, J Qu, GH Liu, T Misteli Cell 165 (6), 1361-1374, 2016 | 503 | 2016 |
| Single-cell transcriptomic atlas of primate ovarian aging S Wang, Y Zheng, J Li, Y Yu, W Zhang, M Song, Z Liu, Z Min, H Hu, Y Jing, ... Cell 180 (3), 585-600. e19, 2020 | 446 | 2020 |
| Progressive degeneration of human neural stem cells caused by pathogenic LRRK2 GH Liu, J Qu, K Suzuki, E Nivet, M Li, N Montserrat, F Yi, X Xu, S Ruiz, ... Nature 491 (7425), 603-607, 2012 | 416 | 2012 |
| The ageing epigenome and its rejuvenation W Zhang, J Qu, GH Liu, JCI Belmonte Nature reviews Molecular cell biology 21 (3), 137-150, 2020 | 415 | 2020 |
| SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2 H Pan, D Guan, X Liu, J Li, L Wang, J Wu, J Zhou, W Zhang, R Ren, ... Cell research 26 (2), 190-205, 2016 | 330 | 2016 |
| Caloric restriction reprograms the single-cell transcriptional landscape of Rattus norvegicus aging S Ma, S Sun, L Geng, M Song, W Wang, Y Ye, Q Ji, Z Zou, SI Wang, X He, ... Cell 180 (5), 984-1001. e22, 2020 | 301 | 2020 |
| The landscape of aging Y Cai, W Song, J Li, Y Jing, C Liang, L Zhang, X Zhang, W Zhang, B Liu, ... Science China Life Sciences 65 (12), 2354-2454, 2022 | 276 | 2022 |
| Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCs GH Liu, K Suzuki, J Qu, I Sancho-Martinez, F Yi, M Li, S Kumar, E Nivet, ... Cell stem cell 8 (6), 688-694, 2011 | 266 | 2011 |
| A single-cell transcriptomic atlas of human skin aging Z Zou, X Long, Q Zhao, Y Zheng, M Song, S Ma, Y Jing, SI Wang, Y He, ... Developmental cell 56 (3), 383-397. e8, 2021 | 246 | 2021 |
| Epigenetic modifications in cardiovascular aging and diseases W Zhang, M Song, J Qu, GH Liu Circulation research 123 (7), 773-786, 2018 | 241 | 2018 |
| A human circulating immune cell landscape in aging and COVID-19 Y Zheng, X Liu, W Le, L Xie, H Li, W Wen, S Wang, S Ma, Z Huang, J Ye, ... Protein & cell 11 (10), 740-770, 2020 | 232 | 2020 |
| S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by β-amyloid peptide J Qu, T Nakamura, G Cao, EA Holland, SR McKercher, SA Lipton Proceedings of the National Academy of Sciences 108 (34), 14330-14335, 2011 | 212 | 2011 |
| Resurrection of endogenous retroviruses during aging reinforces senescence X Liu, Z Liu, Z Wu, J Ren, Y Fan, L Sun, G Cao, Y Niu, B Zhang, Q Ji, ... Cell 186 (2), 287-304. e26, 2023 | 210 | 2023 |
| Targeted gene correction minimally impacts whole-genome mutational load in human-disease-specific induced pluripotent stem cell clones K Suzuki, C Yu, J Qu, M Li, X Yao, T Yuan, A Goebl, S Tang, R Ren, ... Cell stem cell 15 (1), 31-36, 2014 | 206 | 2014 |
| Biomarkers of aging Aging Biomarker Consortium, H Bao, J Cao, M Chen, M Chen, W Chen, ... Science China Life Sciences 66 (5), 893-1066, 2023 | 201* | 2023 |
Guang-Hui LiuChinese Academy of SciencesVerifierad e-postadress på ioz.ac.cn