Role of the polycomb protein EED in the propagation of repressive histone marks R Margueron, N Justin, K Ohno, ML Sharpe, J Son, WJ Drury Iii, P Voigt, ... Nature 461 (7265), 762-767, 2009 | 1343 | 2009 |
Asymmetrically modified nucleosomes P Voigt, G LeRoy, WJ Drury, BM Zee, J Son, DB Beck, NL Young, ... Cell 151 (1), 181-193, 2012 | 491 | 2012 |
Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA S Kaneko, G Li, J Son, CF Xu, R Margueron, TA Neubert, D Reinberg Genes & development 24 (23), 2615-2620, 2010 | 445 | 2010 |
Interactions between JARID2 and noncoding RNAs regulate PRC2 recruitment to chromatin S Kaneko, R Bonasio, R Saldaña-Meyer, T Yoshida, J Son, K Nishino, ... Molecular cell 53 (2), 290-300, 2014 | 409 | 2014 |
Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity I Pinheiro, R Margueron, N Shukeir, M Eisold, C Fritzsch, FM Richter, ... Cell 150 (5), 948-960, 2012 | 369 | 2012 |
PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells S Kaneko, J Son, SS Shen, D Reinberg, R Bonasio Nature structural & molecular biology 20 (11), 1258-1264, 2013 | 343 | 2013 |
Nascent RNA interaction keeps PRC2 activity poised and in check S Kaneko, J Son, R Bonasio, SS Shen, D Reinberg Genes & development 28 (18), 1983-1988, 2014 | 228 | 2014 |
Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin J Son, SS Shen, R Margueron, D Reinberg Genes & development 27 (24), 2663-2677, 2013 | 219 | 2013 |
When β‐cells fail: lessons from dedifferentiation D Accili, SC Talchai, JY Kim‐Muller, F Cinti, E Ishida, AM Ordelheide, ... Diabetes, Obesity and Metabolism 18, 117-122, 2016 | 120 | 2016 |
BACH2 inhibition reverses β cell failure in type 2 diabetes models J Son, H Ding, TB Farb, AM Efanov, J Sun, JL Gore, SK Syed, Z Lei, ... The Journal of clinical investigation 131 (24), 2021 | 58 | 2021 |
Reversing pancreatic β-cell dedifferentiation in the treatment of type 2 diabetes J Son, D Accili Experimental & Molecular Medicine 55 (8), 1652-1658, 2023 | 50 | 2023 |
Cyb5r3 links FoxO1-dependent mitochondrial dysfunction with β-cell failure J Fan, W Du, JY Kim-Muller, J Son, T Kuo, D Larrea, C Garcia, T Kitamoto, ... Molecular metabolism 34, 97-111, 2020 | 36 | 2020 |
Chromatin in the nuclear landscape DB Beck, R Bonasio, S Kaneko, G Li, R Margueron, H Oda, K Sarma, ... Cold Spring Harbor symposia on quantitative biology, sqb. 2010.75. 052, 2011 | 35 | 2011 |
Genetic and pharmacologic inhibition of ALDH1A3 as a treatment of β-cell failure J Son, W Du, M Esposito, K Shariati, H Ding, Y Kang, D Accili Nature communications 14 (1), 558, 2023 | 25 | 2023 |
Pharmacological conversion of gut epithelial cells into insulin-producing cells lowers glycemia in diabetic animals W Du, J Wang, T Kuo, L Wang, WM McKimpson, J Son, H Watanabe, ... The Journal of Clinical Investigation 132 (24), 2022 | 13 | 2022 |
Identification of enteroviruses by using monoclonal antibodies against a putative common epitope SY Shin, KS Kim, YS Lee, YS Chung, KS Park, DS Cheon, BK Na, Y Kang, ... Journal of clinical microbiology 41 (7), 3028-3034, 2003 | 13 | 2003 |
Notch-mediated Ephrin signaling disrupts islet architecture and β cell function A Bartolomé, N Suda, J Yu, C Zhu, J Son, H Ding, A Califano, D Accili, ... JCI insight 7 (6), e157694, 2022 | 11 | 2022 |
Cyb5r3-based mechanism and reversal of secondary failure to sulfonylurea in diabetes H Watanabe, W Du, J Son, L Sui, S Asahara, IJ Kurland, T Kuo, ... Science translational medicine 15 (681), eabq4126, 2023 | 7 | 2023 |
AFF3 and BACH2 are master regulators of metabolic inflexibility, β/α-cell transition, and dedifferentiation in type 2 diabetes J Son, H Ding, D Accii, A Califano bioRxiv, 768135, 2019 | 6 | 2019 |
Molecular genetic characterization of a Korean split hand/split foot malformation (SHFM) YS Kang, HM Cheong, Y Moon, IB Lee, SM Kim, HS Kim, SY Jun, ... Molecules and Cells 17 (3), 397-403, 2004 | 6 | 2004 |