NMDA receptor structures reveal subunit arrangement and pore architecture CH Lee, W Lü, JC Michel, A Goehring, J Du, X Song, E Gouaux Nature 511 (7508), 191-197, 2014 | 582 | 2014 |
Glycine receptor mechanism elucidated by electron cryo-microscopy J Du, W Lü, S Wu, Y Cheng, E Gouaux Nature 526 (7572), 224-229, 2015 | 446 | 2015 |
X-ray structures define human P2X3 receptor gating cycle and antagonist action SE Mansoor, W Lü, W Oosterheert, M Shekhar, E Tajkhorshid, E Gouaux Nature 538 (7623), 66-71, 2016 | 267 | 2016 |
A structural overview of the ion channels of the TRPM family Y Huang, R Fliegert, AH Guse, W Lü, J Du Cell Calcium 85, 102111, 2020 | 192 | 2020 |
Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation W Lü, J Du, A Goehring, E Gouaux Science 355 (6331), eaal3729, 2017 | 192 | 2017 |
Electron cryo-microscopy structure of a human TRPM4 channel PA Winkler, Y Huang, W Sun, J Du, W Lü Nature 552 (7684), 200-204, 2017 | 190 | 2017 |
Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium Y Huang, PA Winkler, W Sun, W Lü, J Du Nature 562 (7725), 145-149, 2018 | 180 | 2018 |
Structures of human pannexin 1 reveal ion pathways and mechanism of gating Z Ruan, IJ Orozco, J Du, W Lü Nature 584 (7822), 646-651, 2020 | 169 | 2020 |
Structure of the human lipid-gated cation channel TRPC3 C Fan, W Choi, W Sun, J Du, W Lü Elife 7, e36852, 2018 | 143 | 2018 |
Mechanism of gating and partial agonist action in the glycine receptor J Yu, H Zhu, R Lape, T Greiner, J Du, W Lü, L Sivilotti, E Gouaux Cell 184 (4), 957-968. e21, 2021 | 128 | 2021 |
pH-dependent gating in a FocA formate channel W Lü, J Du, T Wacker, E Gerbig-Smentek, SLA Andrade, O Einsle Science 332 (6027), 352-354, 2011 | 125 | 2011 |
The formate channel FocA exports the products of mixed-acid fermentation W Lü, J Du, NJ Schwarzer, E Gerbig-Smentek, O Einsle, SLA Andrade Proceedings of the National Academy of Sciences 109 (33), 13254-13259, 2012 | 103 | 2012 |
Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel Y Huang, B Roth, W Lü, J Du Elife 8, e50175, 2019 | 102 | 2019 |
The formate/nitrite transporter family of anion channels W Lü, J Du, NJ Schwarzer, T Wacker, SLA Andrade, O Einsle Biological chemistry 394 (6), 715-727, 2013 | 92 | 2013 |
The structures and gating mechanism of human calcium homeostasis modulator 2 W Choi, N Clemente, W Sun, J Du, W Lü Nature 576 (7785), 163-167, 2019 | 85 | 2019 |
Molecular characteristics of Clostridium perfringens TpeL toxin and consequences of mono-O-GlcNAcylation of Ras in living cells G Guttenberg, S Hornei, T Jank, C Schwan, W Lü, O Einsle, ... Journal of Biological Chemistry 287 (30), 24929-24940, 2012 | 77 | 2012 |
Active-site remodelling in the bifunctional fructose-1, 6-bisphosphate aldolase/phosphatase J Du, RF Say, W Lü, G Fuchs, O Einsle Nature 478 (7370), 534-537, 2011 | 77 | 2011 |
Structural and functional characterization of the nitrite channel NirC from Salmonella typhimurium W Lü, NJ Schwarzer, J Du, E Gerbig-Smentek, SLA Andrade, O Einsle Proceedings of the National Academy of Sciences 109 (45), 18395-18400, 2012 | 75 | 2012 |
Proton-activated chloride channel PAC regulates endosomal acidification and transferrin receptor-mediated endocytosis J Osei-Owusu, J Yang, KH Leung, Z Ruan, W Lü, Y Krishnan, Z Qiu Cell reports 34 (4), 2021 | 55 | 2021 |
Structures and pH-sensing mechanism of the proton-activated chloride channel Z Ruan, J Osei-Owusu, J Du, Z Qiu, W Lü Nature 588 (7837), 350-354, 2020 | 54 | 2020 |