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Keir Menzies
Keir Menzies
Associate Professor, University of Ottawa
Verifierad e-postadress på uottawa.ca - Startsida
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NAD+ metabolism and the control of energy homeostasis: a balancing act between mitochondria and the nucleus
C Cantó, KJ Menzies, J Auwerx
Cell metabolism 22 (1), 31-53, 2015
16482015
NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice
H Zhang, D Ryu, Y Wu, K Gariani, X Wang, P Luan, D D’Amico, ...
Science 352 (6292), 1436-1443, 2016
12422016
Mitochondrial function and apoptotic susceptibility in aging skeletal muscle
B Chabi, V Ljubicic, KJ Menzies, JH Huang, A Saleem, DA Hood
Aging cell 7 (1), 2-12, 2008
5052008
Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice
K Gariani, KJ Menzies, D Ryu, CJ Wegner, X Wang, ER Ropelle, ...
Hepatology 63 (4), 1190-1204, 2016
4002016
Protein acetylation in metabolism—metabolites and cofactors
KJ Menzies, H Zhang, E Katsyuba, J Auwerx
Nature Reviews Endocrinology 12 (1), 43-60, 2016
3512016
NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation
D Ryu, H Zhang, ER Ropelle, V Sorrentino, DAG Mázala, L Mouchiroud, ...
Science translational medicine 8 (361), 361ra139-361ra139, 2016
2992016
Repairing mitochondrial dysfunction in disease
V Sorrentino, KJ Menzies, J Auwerx
Annual review of pharmacology and toxicology 58 (1), 353-389, 2018
2952018
Pharmacological Inhibition of poly (ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle
E Pirinen, C Canto, YS Jo, L Morato, H Zhang, KJ Menzies, EG Williams, ...
Cell metabolism 19 (6), 1034-1041, 2014
2952014
The role of mitochondria in stem cell fate and aging
H Zhang, KJ Menzies, J Auwerx
Development 145 (8), dev143420, 2018
2802018
Sirtuin 1-mediated effects of exercise and resveratrol on mitochondrial biogenesis
KJ Menzies, K Singh, A Saleem, DA Hood
Journal of Biological Chemistry 288 (10), 6968-6979, 2013
2142013
Differential susceptibility of subsarcolemmal and intermyofibrillar mitochondria to apoptotic stimuli
PJ Adhihetty, V Ljubicic, KJ Menzies, DA Hood
American journal of physiology-cell physiology 289 (4), C994-C1001, 2005
2052005
Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease
K Gariani, D Ryu, KJ Menzies, HS Yi, S Stein, H Zhang, A Perino, ...
Journal of hepatology 66 (1), 132-141, 2017
1742017
Sarcopenia and muscle aging: a brief overview
T Dao, AE Green, YA Kim, SJ Bae, KT Ha, K Gariani, M Lee, KJ Menzies, ...
Endocrinology and metabolism 35 (4), 716-732, 2020
1722020
SIRT2 deficiency modulates macrophage polarization and susceptibility to experimental colitis
G Lo Sasso, KJ Menzies, A Mottis, A Piersigilli, A Perino, H Yamamoto, ...
PloS one 9 (7), e103573, 2014
1402014
SUMOylation-dependent LRH-1/PROX1 interaction promotes atherosclerosis by decreasing hepatic reverse cholesterol transport
S Stein, MH Oosterveer, C Mataki, P Xu, V Lemos, R Havinga, C Dittner, ...
Cell metabolism 20 (4), 603-613, 2014
922014
Relationship between Sirt1 expression and mitochondrial proteins during conditions of chronic muscle use and disuse
B Chabi, PJ Adhihetty, MFN O'Leary, KJ Menzies, DA Hood
Journal of applied physiology 107 (6), 1730-1735, 2009
842009
Exercise-induced mitochondrial biogenesis in skeletal muscle
DA Hood, B Chabi, K Menzies, M O’Leary, D Walkinshaw
Role of Physical Exercise in Preventing Disease and Improving the Quality of …, 2007
732007
The role of SirT1 in muscle mitochondrial turnover
KJ Menzies, DA Hood
Mitochondrion 12 (1), 5-13, 2012
662012
Proteomics characterization of mitochondrial‐derived vesicles under oxidative stress
G Vasam, R Nadeau, VJJ Cadete, M Lavallée‐Adam, KJ Menzies, ...
The FASEB Journal 35 (4), 2021
612021
Mitochondrial dysfunction is associated with a pro-apoptotic cellular environment in senescent cardiac muscle
V Ljubicic, KJ Menzies, DA Hood
Mechanisms of ageing and development 131 (2), 79-88, 2010
542010
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Artiklar 1–20