| Lipid metabolism in sickness and in health: Emerging regulators of lipotoxicity H Yoon, JL Shaw, MC Haigis, A Greka Molecular cell 81 (18), 3708-3730, 2021 | 272 | 2021 |
| A high-content screen for mucin-1-reducing compounds identifies fostamatinib as a candidate for rapid repurposing for acute lung injury M Kost-Alimova, EH Sidhom, A Satyam, BT Chamberlain, M Dvela-Levitt, ... Cell Reports Medicine 1 (8), 2020 | 44 | 2020 |
| Nebula/DSCR1 upregulation delays neurodegeneration and protects against APP-induced axonal transport defects by restoring calcineurin and GSK-3β signaling JL Shaw, KT Chang PLoS genetics 9 (9), e1003792, 2013 | 42 | 2013 |
| Targeting a Braf/Mapk pathway rescues podocyte lipid peroxidation in CoQ-deficiency kidney disease EH Sidhom, C Kim, M Kost-Alimova, MT Ting, K Keller, J Avila-Pacheco, ... The Journal of clinical investigation 131 (5), 2021 | 41 | 2021 |
| A rare kidney disease to cure them all? Towards mechanism-based therapies for proteinopathies M Dvela-Levitt, JL Shaw, A Greka Trends in Molecular Medicine 27 (4), 394-409, 2021 | 22 | 2021 |
| A high content screen for mucin-1-reducing compounds identifies fostamatinib as a candidate for rapid repurposing for acute lung injury during the COVID-19 pandemic M Alimova, EH Sidhom, A Satyam, M Dvela-Levitt, M Melanson, ... bioRxiv, 2020 | 21 | 2020 |
| Maintenance of stem cell niche integrity by a novel activator of integrin signaling JY Lee, JY Chen, JL Shaw, KT Chang PLoS Genetics 12 (5), e1006043, 2016 | 21 | 2016 |
| FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity N Wieder, JC Fried, C Kim, EH Sidhom, MR Brown, JL Marshall, ... Cell metabolism 35 (5), 887-905. e11, 2023 | 18 | 2023 |
| Bidirectional regulation of amyloid precursor protein-induced memory defects by Nebula/DSCR1: a protein upregulated in alzheimer's disease and down syndrome JL Shaw, S Zhang, KT Chang Journal of Neuroscience 35 (32), 11374-11383, 2015 | 17 | 2015 |
| Obesity-instructed TREM2high macrophages identified by comparative analysis of diabetic mouse and human kidney at single cell resolution A Subramanian, K Vernon, Y Zhou, JL Marshall, M Alimova, F Zhang, ... bioRxiv, 2021.05. 30.446342, 2021 | 11 | 2021 |
| Protective role for kidney TREM2high macrophages in obesity-and diabetes-induced kidney injury A Subramanian, KA Vernon, Y Zhou, JL Marshall, M Alimova, C Arevalo, ... Cell Reports 43 (6), 2024 | 9 | 2024 |
| Mechanisms of protein trafficking and quality control in the kidney and beyond JL Shaw, JL Pablo, A Greka Annual Review of Physiology 85 (1), 407-423, 2023 | 4 | 2023 |
| Disrupted uromodulin trafficking is rescued by targeting TMED cargo receptors S Bazua-Valenti, MR Brown, J Zavras, MR Khursigara, E Grinkevich, ... The Journal of Clinical Investigation 134 (24), 2024 | | 2024 |
| Unraveling the conformational dynamics of UMOD protein variants in autosomal dominant tubulointerstitial kidney disease: Insights from molecular dynamics simulations S Kwon, J Safer, J Lin, FM Arines, H Yoo, S Bazúa, K Keller, J Shaw, ... Biophysical Journal 123 (3), 15a, 2024 | | 2024 |
| # 3186 INVESTIGATING TREM2 MACROPHAGES IN CHRONIC KIDNEY DISEASE G Trivioli, N Richoz, A Subramanian, K Vernon, P Trotter, Y Zhou, J Shaw, ... Nephrology Dialysis Transplantation 38 (Supplement_1), gfad063d_3186, 2023 | | 2023 |
| Unraveling Fundamental Mechanisms of UMOD Quality Control and Their Role in UMOD-Associated CKD: PO1248 S Bazua-Valenti, EH Sidhom, V Padovano, J Roignot, KH Keller, ... Journal of the American Society of Nephrology 32 (10S), 403, 2021 | | 2021 |
| GDC-0879 Rescues Lipid Peroxidation and Podocyte Dysfunction in Coenzyme Q-Deficient Kidney Disease: PO1988 EH Sidhom, C Kim, M Alimova, MT Ting, JR Avila-Pacheco, AJ Watts, ... Journal of the American Society of Nephrology 31 (10S), 613, 2020 | | 2020 |
| Nebula/DSCR1 upregulation preserves axonal transport and memory function in a Drosophila model for Alzheimer's disease JLS Shaw Journal of Neuroscience, 2015 | | 2015 |