Evolution and diversity of assembly-line polyketide synthases: focus review A Nivina, KP Yuet, J Hsu, C Khosla Chemical reviews 119 (24), 12524-12547, 2019 | 281 | 2019 |
The integron: adaptation on demand JA Escudero, C Loot, A Nivina, D Mazel Microbiology spectrum 3 (2), 10.1128/microbiolspec. mdna3-0019-2014, 2015 | 226 | 2015 |
Efficiency of integron cassette insertion in correct orientation is ensured by the interplay of the three unpaired features of attC recombination sites A Nivina, JA Escudero, C Vit, D Mazel, C Loot Nucleic acids research 44 (16), 7792-7803, 2016 | 56 | 2016 |
Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation JA Escudero, C Loot, V Parissi, A Nivina, C Bouchier, D Mazel Nature communications 7 (1), 10937, 2016 | 40 | 2016 |
Engineering of chimeric polyketide synthases using SYNZIP docking domains M Klaus, AD D’Souza, A Nivina, C Khosla, M Grininger ACS chemical biology 14 (3), 426-433, 2019 | 38 | 2019 |
Differences in integron cassette excision dynamics shape a trade-off between evolvability and genetic capacitance C Loot, A Nivina, J Cury, JA Escudero, M Ducos-Galand, D Bikard, ... MBio 8 (2), 10.1128/mbio. 02296-16, 2017 | 37 | 2017 |
Dynamic stepwise opening of integron attC DNA hairpins by SSB prevents toxicity and ensures functionality MS Grieb, A Nivina, BL Cheeseman, A Hartmann, D Mazel, M Schlierf Nucleic acids research 45 (18), 10555-10563, 2017 | 35 | 2017 |
Structural heterogeneity of attC integron recombination sites revealed by optical tweezers A Mukhortava, M Pöge, MS Grieb, A Nivina, C Loot, D Mazel, M Schlierf Nucleic acids research 47 (4), 1861-1870, 2019 | 23 | 2019 |
Structure-specific DNA recombination sites: Design, validation, and machine learning–based refinement A Nivina, MS Grieb, C Loot, D Bikard, J Cury, L Shehata, J Bernardes, ... Science advances 6 (30), eaay2922, 2020 | 21 | 2020 |
GRINS: Genetic elements that recode assembly-line polyketide synthases and accelerate their diversification A Nivina, S Herrera Paredes, HB Fraser, C Khosla Proceedings of the National Academy of Sciences 118 (26), e2100751118, 2021 | 20 | 2021 |
The Integron: Adaptation On Demand. Microbiol Spectr. 2015; 3 (2): MDNA3-0019-2014. doi: 10.1128/microbiolspec JA Escudero, C Loot, A Nivina, D Mazel MDNA3-0019-2014, 0 | 11 | |
Primary and promiscuous functions coexist during evolutionary innovation through whole protein domain acquisitions JA Escudero, A Nivina, HE Kemble, C Loot, O Tenaillon, D Mazel Elife 9, e58061, 2020 | 9 | 2020 |
Integron identification in bacterial genomes and cassette recombination assays C Vit, C Loot, JA Escudero, A Nivina, D Mazel Horizontal Gene Transfer: Methods and Protocols, 189-208, 2020 | 8 | 2020 |
Recoding of synonymous genes to expand evolutionary landscapes requires control of secondary structure affecting translation JA Escudero, A Nivina, G Cambray, R López‐Igual, C Loot, D Mazel Biotechnology and Bioengineering 115 (1), 184-191, 2018 | 6 | 2018 |
The Integron: Adaptation On Demand. Microbiol. Spectr. 2015, 3 JA Escudero, C Loot, A Nivina, D Mazel MDNA3-0019-2014.[CrossRef][PubMed], 0 | 5 | |
Identification of polyketide biosynthetic gene clusters that harbor self-resistance target genes GA Vandova, A Nivina, C Khosla, RW Davis, CR Fisher, ME Hillenmeyer BioRxiv, 2020.06. 01.128595, 2020 | 4 | 2020 |
Synthetic attc recombination sites for protein domain shuffling D Mazel, A Nivina, D Bikard, MS Grieb US Patent App. 16/316,476, 2020 | | 2020 |
DNA Secondary Structure Formation in Bacterial Gene Capture Systems at Single-Molecule Resolution M Swoboda, MS Grieb, V Natarajan, A Nivina, D Mazel, M Schlierf Biophysical Journal 106 (2), 272a-273a, 2014 | | 2014 |