| Molecular basis of antimony treatment in leishmaniasis P Baiocco, G Colotti, S Franceschini, A Ilari Journal of medicinal chemistry 52 (8), 2603-2612, 2009 | 349 | 2009 |
| Taxanes in cancer treatment: Activity, chemoresistance and its overcoming L Mosca, A Ilari, F Fazi, YG Assaraf, G Colotti Drug Resistance Updates 54, 100742, 2021 | 251 | 2021 |
| Metal regulation of siderophore synthesis in Pseudomonas aeruginosa and functional effects of siderophore-metal complexes P Visca, G Colotti, L Serino, D Verzili, N Orsi, E Chiancone Applied and environmental microbiology 58 (9), 2886-2893, 1992 | 216 | 1992 |
| Polyamine metabolism in Leishmania: from arginine to trypanothione G Colotti, A Ilari Amino acids 40 (2), 269-285, 2011 | 196 | 2011 |
| A gold-containing drug against parasitic polyamine metabolism: the X-ray structure of trypanothione reductase from Leishmania infantum in complex with auranofin … A Ilari, P Baiocco, L Messori, A Fiorillo, A Boffi, M Gramiccia, T Di Muccio, ... Amino acids 42, 803-811, 2012 | 189 | 2012 |
| Not only P-glycoprotein: Amplification of the ABCB1-containing chromosome region 7q21 confers multidrug resistance upon cancer cells by coordinated overexpression of an … I Genovese, A Ilari, YG Assaraf, F Fazi, G Colotti Drug Resistance Updates 32, 23-46, 2017 | 161 | 2017 |
| Inhibitory Effect of Silver Nanoparticles on Trypanothione Reductase Activity and Leishmania infantum Proliferation P Baiocco, A Ilari, P Ceci, S Orsini, M Gramiccia, T Di Muccio, G Colotti ACS medicinal chemistry letters 2 (3), 230-233, 2011 | 149 | 2011 |
| Doxorubicin and other anthracyclines in cancers: Activity, chemoresistance and its overcoming R Mattioli, A Ilari, B Colotti, L Mosca, F Fazi, G Colotti Molecular aspects of medicine 93, 101205, 2023 | 128 | 2023 |
| Targeting trypanothione reductase, a key enzyme in the redox trypanosomatid metabolism, to develop new drugs against leishmaniasis and trypanosomiases T Battista, G Colotti, A Ilari, A Fiorillo Molecules 25 (8), 1924, 2020 | 122 | 2020 |
| Inhibition of Leishmania infantum Trypanothione Reductase by Azole‐Based Compounds: a Comparative Analysis with Its Physiological Substrate by X‐ray … P Baiocco, G Poce, S Alfonso, M Cocozza, GC Porretta, G Colotti, M Biava, ... ChemMedChem 8 (7), 1175-1183, 2013 | 92 | 2013 |
| A failure mode and effect analysis (FMEA)-based approach for risk assessment of scientific processes in non-regulated research laboratories A Mascia, AM Cirafici, A Bongiovanni, G Colotti, G Lacerra, M Di Carlo, ... Accreditation and Quality Assurance 25, 311-321, 2020 | 88 | 2020 |
| Selective delivery of doxorubicin by novel stimuli-sensitive nano-ferritins overcomes tumor refractoriness G Fracasso, E Falvo, G Colotti, F Fazi, T Ingegnere, A Amalfitano, ... Journal of Controlled Release 239, 10-18, 2016 | 82 | 2016 |
| Polyamine-trypanothione pathway: an update A Ilari, A Fiorillo, I Genovese, G Colotti Future Medicinal Chemistry 9 (1), 61-77, 2017 | 81 | 2017 |
| Sorcin, a calcium binding protein involved in the multidrug resistance mechanisms in cancer cells G Colotti, E Poser, A Fiorillo, I Genovese, V Chiarini, A Ilari Molecules 19 (9), 13976-13989, 2014 | 81 | 2014 |
| Identification of chalcone-based antileishmanial agents targeting trypanothione reductase M Ortalli, A Ilari, G Colotti, I De Ionna, T Battista, A Bisi, S Gobbi, A Rampa, ... European journal of medicinal chemistry 152, 527-541, 2018 | 78 | 2018 |
| Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking M Brindisi, S Brogi, N Relitti, A Vallone, S Butini, S Gemma, E Novellino, ... Scientific reports 5 (1), 9705, 2015 | 76 | 2015 |
| Structural insights into the enzymes of the trypanothione pathway: targets for antileishmaniasis drugs G Colotti, P Baiocco, A Fiorillo, A Boffi, E Poser, FD Chiaro, A Ilari Future medicinal chemistry 5 (15), 1861-1875, 2013 | 74 | 2013 |
| Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives F Saccoliti, G Angiulli, G Pupo, L Pescatori, VN Madia, A Messore, ... Journal of enzyme inhibition and medicinal chemistry 32 (1), 304-310, 2017 | 72 | 2017 |
| Metals and metal derivatives in medicine G Colotti, A Ilari, A Boffi, V Morea Mini reviews in medicinal chemistry 13 (2), 211-221, 2013 | 70 | 2013 |
| The crystal structures of the tryparedoxin-tryparedoxin peroxidase couple unveil the structural determinants of Leishmania detoxification pathway A Fiorillo, G Colotti, A Boffi, P Baiocco, A Ilari Public Library of Science 6 (8), e1781, 2012 | 65 | 2012 |
