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Keren Hilgendorf
Keren Hilgendorf
Assistant Professor, University of Utah School of Medicine
Verifierad e-postadress på biochem.utah.edu - Startsida
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The primary cilium as a cellular receiver: organizing ciliary GPCR signaling
KI Hilgendorf, CT Johnson, PK Jackson
Current opinion in cell biology 39, 84-92, 2016
2412016
Omega-3 fatty acids activate ciliary FFAR4 to control adipogenesis
KI Hilgendorf, CT Johnson, A Mezger, SL Rice, AM Norris, J Demeter, ...
Cell 179 (6), 1289-1305. e21, 2019
2162019
The retinoblastoma protein induces apoptosis directly at the mitochondria
KI Hilgendorf, ES Leshchiner, S Nedelcu, MA Maynard, E Calo, A Ianari, ...
Genes & development 27 (9), 1003-1015, 2013
1652013
Discovery of ciliary G protein-coupled receptors regulating pancreatic islet insulin and glucagon secretion
CT Wu, KI Hilgendorf, RJ Bevacqua, Y Hang, J Demeter, SK Kim, ...
Genes & Development 35 (17-18), 1243-1255, 2021
572021
Primary cilia on muscle stem cells are critical to maintain regenerative capacity and are lost during aging
AR Palla, KI Hilgendorf, AV Yang, JP Kerr, AC Hinken, J Demeter, P Kraft, ...
Nature Communications 13 (1), 1439, 2022
492022
Emerging mechanistic understanding of cilia function in cellular signalling
KI Hilgendorf, BR Myers, JF Reiter
Nature Reviews Molecular Cell Biology 25 (7), 555-573, 2024
482024
Bmi1 is required for tumorigenesis in a mouse model of intestinal cancer
MA Maynard, R Ferretti, KI Hilgendorf, C Perret, P Whyte, JA Lees
Oncogene 33 (28), 3742-3747, 2014
452014
Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration
E Porpiglia, T Mai, P Kraft, CA Holbrook, A de Morree, VD Gonzalez, ...
Cell Stem Cell 29 (12), 1653-1668. e8, 2022
362022
Primary cilia are critical regulators of white adipose tissue expansion
KI Hilgendorf
Frontiers in Physiology 12, 769367, 2021
242021
Ciliary control of adipocyte progenitor cell fate regulates energy storage
SR Scamfer, MD Lee, KI Hilgendorf
Frontiers in Cell and Developmental Biology 10, 1083372, 2022
82022
BMPER is a marker of adipose progenitors and adipocytes and a positive modulator of adipogenesis
JD Garritson, J Zhang, A Achenbach, M Ferhat, E Eich, CJ Stubben, ...
Communications Biology 6 (1), 638, 2023
72023
Zinc-alpha-2-glycoprotein secreted by triple-negative breast cancer promotes Peritumoral fibrosis
S Verma, SD Giagnocavo, MC Curtin, M Arumugam, SM Osburn-Staker, ...
Cancer Research Communications 4 (7), 1655-1666, 2024
62024
Ciliation of muscle stem cells is critical to maintain regenerative capacity and is lost during aging
AR Palla, KI Hilgendorf, AV Yang, JP Kerr, AC Hinken, J Demeter, P Kraft, ...
bioRxiv, 2020.03. 20.000943, 2020
42020
A CRISPR-based genome-wide screen for adipogenesis reveals new insights into mitotic expansion and lipogenesis
RE Turn, KI Hilgendorf, CT Johnson, K Han, A Rabiee, J Demeter, ...
BioRxiv, 2020.07. 13.201038, 2020
22020
Isolation and Culturing of Primary Murine Adipocytes from Lean and Obese Mice
MC Curtin, AE Jackson, KI Hilgendorf
Journal of Visualized Experiments (JoVE), e67846, 2025
2025
Hyperlipidemia drives tumor growth in a mouse model of obesity-accelerated breast cancer growth.
RFL Vieira, SR Sanchez, M Arumugam, PD Mower, MC Curtin, MR Gallop, ...
bioRxiv, 2025.02. 10.637542, 2025
2025
Abstract B020: Lean adipocyte-secreted oxylipin, 9S-HODE, triggers ferroptosis and protects against obesity-accelerated breast cancer
M Curtin, JA Maschek, G Wang, D Lum, JE Cox, KI Hilgendorf
Cancer Research 84 (22_Supplement), B020-B020, 2024
2024
Abstract B031: Lean adipocyte-derived lipid decreases metastatic potential of breast cancer cells
AE Jackson, KI Hilgendorf
Cancer Research 84 (22_Supplement), B031-B031, 2024
2024
318-OR: Ciliary GPCRs Regulate Glucose-Stimulated Insulin Secretion
CT Wu, K Hilgendorf, Y Hang, RJ Bevacqua, CT Johnson, CA Chang, ...
Diabetes 69 (Supplement_1), 2020
2020
Preadipocyte Cell Cycle Control: Hypertrophy or Hyperplasia?
CT Johnson, KI Hilgendorf, K Han, MC Bassik, PK Jackson
MOLECULAR BIOLOGY OF THE CELL 29 (26), 2018
2018
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Artiklar 1–20