| Restoration of TET2 function blocks aberrant self-renewal and leukemia progression L Cimmino, I Dolgalev, Y Wang, A Yoshimi, GH Martin, J Wang, V Ng, ... Cell 170 (6), 1079-1095. e20, 2017 | 702 | 2017 |
| Transcriptional repressor Blimp-1 regulates T cell homeostasis and function GA Martins, L Cimmino, M Shapiro-Shelef, M Szabolcs, A Herron, ... Nature immunology 7 (5), 457-465, 2006 | 481 | 2006 |
| DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia R Rampal, A Alkalin, J Madzo, A Vasanthakumar, E Pronier, J Patel, Y Li, ... Cell reports 9 (5), 1841-1855, 2014 | 312 | 2014 |
| TET family proteins and their role in stem cell differentiation and transformation L Cimmino, O Abdel-Wahab, RL Levine, I Aifantis Cell stem cell 9 (3), 193-204, 2011 | 293 | 2011 |
| B vitamins and one-carbon metabolism: implications in human health and disease P Lyon, V Strippoli, B Fang, L Cimmino Nutrients 12 (9), 2867, 2020 | 273 | 2020 |
| Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia AH Shih, Y Jiang, C Meydan, K Shank, S Pandey, L Barreyro, ... Cancer cell 27 (4), 502-515, 2015 | 258 | 2015 |
| Hacking macrophage-associated immunosuppression for regulating glioblastoma angiogenesis X Cui, RTT Morales, W Qian, H Wang, JP Gagner, I Dolgalev, ... Biomaterials 161, 164-178, 2018 | 250 | 2018 |
| TET1 is a tumor suppressor of hematopoietic malignancy L Cimmino, MM Dawlaty, D Ndiaye-Lobry, YS Yap, S Bakogianni, Y Yu, ... Nature immunology 16 (6), 653-662, 2015 | 240 | 2015 |
| Stage-specific control of early B cell development by the transcription factor Ikaros TA Schwickert, H Tagoh, S Gültekin, A Dakic, E Axelsson, M Minnich, ... Nature immunology 15 (3), 283-293, 2014 | 238 | 2014 |
| Blimp-1 directly represses Il2 and the Il2 activator Fos, attenuating T cell proliferation and survival GA Martins, L Cimmino, J Liao, E Magnusdottir, K Calame The Journal of experimental medicine 205 (9), 1959-1965, 2008 | 238 | 2008 |
| Mutant IDH1 downregulates ATM and alters DNA repair and sensitivity to DNA damage independent of TET2 S Inoue, WY Li, A Tseng, I Beerman, AJ Elia, SC Bendall, F Lemonnier, ... Cancer cell 30 (2), 337-348, 2016 | 226 | 2016 |
| Vitamin C in stem cell reprogramming and cancer L Cimmino, BG Neel, I Aifantis Trends in cell biology 28 (9), 698-708, 2018 | 216 | 2018 |
| Blimp-1 attenuates Th1 differentiation by repression of ifng, tbx21, and bcl6 gene expression L Cimmino, GA Martins, J Liao, E Magnusdottir, G Grunig, RK Perez, ... The Journal of Immunology 181 (4), 2338-2347, 2008 | 205 | 2008 |
| Notch pathway activation targets AML-initiating cell homeostasis and differentiation C Lobry, P Ntziachristos, D Ndiaye-Lobry, P Oh, L Cimmino, N Zhu, ... Journal of Experimental Medicine 210 (2), 301-319, 2013 | 194 | 2013 |
| Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms J Mullenders, B Aranda-Orgilles, P Lhoumaud, M Keller, J Pae, K Wang, ... Journal of Experimental Medicine 212 (11), 1833-1850, 2015 | 179 | 2015 |
| TET2 deficiency causes germinal center hyperplasia, impairs plasma cell differentiation, and promotes B-cell lymphomagenesis PM Dominguez, H Ghamlouch, W Rosikiewicz, P Kumar, W Béguelin, ... Cancer discovery 8 (12), 1632-1653, 2018 | 168 | 2018 |
| Reprogramming the epigenome with vitamin C T Lee Chong, EL Ahearn, L Cimmino Frontiers in cell and developmental biology 7, 128, 2019 | 131 | 2019 |
| Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia GJ Liu, L Cimmino, JG Jude, Y Hu, MT Witkowski, MD McKenzie, ... Genes & development 28 (12), 1337-1350, 2014 | 117 | 2014 |
| Tet2 facilitates the derepression of myeloid target genes during CEBPα-induced transdifferentiation of pre-B cells EM Kallin, J Rodríguez-Ubreva, J Christensen, L Cimmino, I Aifantis, ... Molecular cell 48 (2), 266-276, 2012 | 107 | 2012 |
| The impact of DNA methylation in hematopoietic malignancies M Guillamot, L Cimmino, I Aifantis Trends in cancer 2 (2), 70-83, 2016 | 93 | 2016 |
Ross DickinsAssociate Professor, Monash University (Australian Centre for Blood Diseases)Verifierad e-postadress på monash.edu