| Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein C Balducci, M Beeg, M Stravalaci, A Bastone, A Sclip, E Biasini, L Tapella, ... Proceedings of the National Academy of Sciences 107 (5), 2295-2300, 2010 | 610 | 2010 |
| Transgenic fatal familial insomnia mice indicate prion infectivity-independent mechanisms of pathogenesis and phenotypic expression of disease I Bouybayoune, S Mantovani, F Del Gallo, I Bertani, E Restelli, L Comerio, ... PLoS pathogens 11 (4), e1004796, 2015 | 80 | 2015 |
| Conjugated polymers optically regulate the fate of endothelial colony-forming cells F Lodola, V Rosti, G Tullii, A Desii, L Tapella, P Catarsi, D Lim, F Moccia, ... Science advances 5 (9), eaav4620, 2019 | 75 | 2019 |
| Ca2+ handling at the mitochondria-ER contact sites in neurodegeneration D Lim, G Dematteis, L Tapella, AA Genazzani, T Calì, M Brini, ... Cell Calcium 98, 102453, 2021 | 70 | 2021 |
| Proteomic analysis links alterations of bioenergetics, mitochondria-ER interactions and proteostasis in hippocampal astrocytes from 3xTg-AD mice G Dematteis, G Vydmantaitė, FA Ruffinatti, M Chahin, S Farruggio, ... Cell Death & Disease 11 (8), 645, 2020 | 67 | 2020 |
| Gene expression, proteome and calcium signaling alterations in immortalized hippocampal astrocytes from an Alzheimer’s disease mouse model F Rocchio, L Tapella, M Manfredi, M Chisari, F Ronco, FA Ruffinatti, ... Cell Death & Disease 10 (1), 24, 2019 | 39 | 2019 |
| Deletion of calcineurin from GFAP‐expressing astrocytes impairs excitability of cerebellar and hippocampal neurons through astroglial Na+/K+ ATPase L Tapella, T Soda, L Mapelli, V Bortolotto, H Bondi, FA Ruffinatti, ... Glia 68 (3), 543-560, 2020 | 30 | 2020 |
| The endoplasmic reticulum stress and unfolded protein response in Alzheimer’s disease: a calcium dyshomeostasis perspective D Lim, L Tapella, G Dematteis, AA Genazzani, M Corazzari, A Verkhratsky Ageing research reviews 87, 101914, 2023 | 29 | 2023 |
| TGF‐β2 and TGF‐β3 from cultured β‐amyloid‐treated or 3xTg‐AD‐derived astrocytes may mediate astrocyte–neuron communication L Tapella, M Cerruti, I Biocotino, A Stevano, F Rocchio, PL Canonico, ... European Journal of Neuroscience 47 (3), 211-221, 2018 | 28 | 2018 |
| The hydrophobic core region governs mutant prion protein aggregation and intracellular retention E Biasini, L Tapella, E Restelli, M Pozzoli, T Massignan, R Chiesa Biochemical Journal 430 (3), 477-486, 2010 | 28 | 2010 |
| Immunopurification of pathological prion protein aggregates E Biasini, L Tapella, S Mantovani, M Stravalaci, M Gobbi, DA Harris, ... PLoS One 4 (11), e7816, 2009 | 25 | 2009 |
| Benzene and 2-ethyl-phthalate induce proliferation in normal rat pituitary cells L Tapella, A Sesta, MF Cassarino, V Zunino, MG Catalano, ... Pituitary 20, 311-318, 2017 | 23 | 2017 |
| Calcineurin signalling in astrocytes: from pathology to physiology and control of neuronal functions D Lim, L Tapella, G Dematteis, M Talmon, AA Genazzani Neurochemical Research 48 (4), 1077-1090, 2023 | 22 | 2023 |
| Protein synthesis inhibition and loss of homeostatic functions in astrocytes from an Alzheimer’s disease mouse model: a role for ER-mitochondria interaction L Tapella, G Dematteis, M Moro, B Pistolato, E Tonelli, VV Vanella, ... Cell death & disease 13 (10), 878, 2022 | 21 | 2022 |
| The anti-prion antibody 15B3 detects toxic amyloid-β oligomers M Stravalaci, L Tapella, M Beeg, A Rossi, P Joshi, E Pizzi, M Mazzanti, ... Journal of Alzheimer's Disease 53 (4), 1485-1497, 2016 | 17 | 2016 |
| Calcineurin controls expression of EAAT1/GLAST in mouse and human cultured astrocytes through dynamic regulation of protein synthesis and degradation G Dematteis, E Restelli, R Chiesa, E Aronica, AA Genazzani, D Lim, ... International journal of molecular sciences 21 (6), 2213, 2020 | 14 | 2020 |
| Transcriptional remodeling in primary hippocampal astrocytes from an Alzheimer's disease mouse model F Ruffinatti, L Tapella, I Gregnanin, A Stevano, G Chiorino, PL Canonico, ... Current Alzheimer Research 15 (11), 986-1004, 2018 | 14 | 2018 |
| Epitope scanning indicates structural differences in brain-derived monomeric and aggregated mutant prion proteins related to genetic prion diseases L Tapella, M Stravalaci, A Bastone, E Biasini, M Gobbi, R Chiesa Biochemical Journal 454 (3), 417-425, 2013 | 13 | 2013 |
| Immortalized Alzheimer’s disease astrocytes: characterization of their proteolytic systems C Gong, L Bonfili, Y Zheng, V Cecarini, M Cuccioloni, M Angeletti, ... Molecular Neurobiology 60 (5), 2787-2800, 2023 | 12 | 2023 |
| Deletion of calcineurin from astrocytes reproduces proteome signature of Alzheimer's disease and epilepsy and predisposes to seizures L Tapella, G Dematteis, FA Ruffinatti, L Ponzoni, F Fiordaliso, A Corbelli, ... Cell Calcium 100, 102480, 2021 | 10 | 2021 |
