| Synthesis of CDDO–amino acid–nitric oxide donor trihybrids as potential antitumor agents against both drug-sensitive and drug-resistant colon cancer Y Ai, F Kang, Z Huang, X Xue, Y Lai, S Peng, J Tian, Y Zhang Journal of Medicinal Chemistry 58 (5), 2452-2464, 2015 | 79 | 2015 |
| Discovery of new monocarbonyl ligustrazine–curcumin hybrids for intervention of drug-sensitive and drug-resistant lung cancer Y Ai, B Zhu, C Ren, F Kang, J Li, Z Huang, Y Lai, S Peng, K Ding, J Tian, ... Journal of medicinal chemistry 59 (5), 1747-1760, 2016 | 76 | 2016 |
| Gallium(III)–Salophen as a Dual Inhibitor of Pseudomonas aeruginosa Heme Sensing and Iron Acquisition G Centola, DJ Deredge, K Hom, Y Ai, AT Dent, F Xue, A Wilks ACS infectious diseases 6 (8), 2073-2085, 2020 | 48 | 2020 |
| Identification of thiourea-based inhibitors of the B-cell lymphoma 6 BTB domain via NMR-based fragment screening and computer-aided drug design H Cheng, BM Linhares, W Yu, MG Cardenas, Y Ai, W Jiang, A Winkler, ... Journal of medicinal chemistry 61 (17), 7573-7588, 2018 | 45 | 2018 |
| Serum Elabela/Toddler levels are associated with albuminuria in patients with type 2 diabetes H Zhang, D Gong, L Ni, L Shi, W Xu, M Shi, J Chen, Y Ai, X Zhang Cellular Physiology and Biochemistry 48 (3), 1347-1354, 2018 | 43 | 2018 |
| Synthesis and in vitro antiproliferative evaluation of pyrimido [5, 4-c] quinoline-4-(3H)-one derivatives Y Ai, YJ Liang, JC Liu, HW He, Y Chen, C Tang, GZ Yang, LW Fu European journal of medicinal chemistry 47, 206-213, 2012 | 43 | 2012 |
| Enhanced tumor selectivity of 5-fluorouracil using a reactive oxygen species-activated prodrug approach Y Ai, ON Obianom, M Kuser, Y Li, Y Shu, F Xue ACS medicinal chemistry letters 10 (1), 127-131, 2018 | 40 | 2018 |
| Pyrazole-4-Carboxamide (YW2065): a therapeutic candidate for Colorectal Cancer via Dual activities of Wnt/β-Catenin signaling inhibition and AMP-Activated protein kinase (AMPK … W Yang, Y Li, Y Ai, ON Obianom, D Guo, H Yang, S Sakamuru, M Xia, ... Journal of medicinal chemistry 62 (24), 11151-11164, 2019 | 37 | 2019 |
| Synthesis and biological evaluation of novel olean-28, 13β-lactams as potential antiprostate cancer agents Y Ai, Y Hu, F Kang, Y Lai, Y Jia, Z Huang, S Peng, H Ji, J Tian, Y Zhang Journal of Medicinal Chemistry 58 (11), 4506-4520, 2015 | 35 | 2015 |
| Olean-28, 13b-olide 2 plays a role in cisplatin-mediated apoptosis and reverses cisplatin resistance in human lung cancer through multiple signaling pathways B Zhu, C Ren, K Du, H Zhu, Y Ai, F Kang, Y Luo, W Liu, L Wang, Y Xu, ... Biochemical Pharmacology 170, 113642, 2019 | 32 | 2019 |
| Nitrogen mustards as anticancer chemotherapies: historic perspective, current developments and future trends B Diethelm-Varela, Y Ai, D Liang, F Xue Current Topics in Medicinal Chemistry 19 (9), 691-712, 2019 | 32 | 2019 |
| Molecular Modeling Studies of 4,5-Dihydro-1H-pyrazolo[4,3-h] quinazoline Derivatives as Potent CDK2/Cyclin A Inhibitors Using 3D-QSAR and Docking Y Ai, ST Wang, PH Sun, FJ Song International Journal of Molecular Sciences 11 (10), 3705-3724, 2010 | 31 | 2010 |
| Tetramethylpyrazine blocks TFAM degradation and up-regulates mitochondrial DNA copy number by interacting with TFAM L Lan, M Guo, Y Ai, F Chen, Y Zhang, L Xia, D Huang, L Niu, Y Zheng, ... Bioscience reports 37 (3), BSR20170319, 2017 | 30 | 2017 |
| Progress toward B-cell lymphoma 6 BTB domain inhibitors for the treatment of diffuse large B-cell lymphoma and beyond Y Ai, L Hwang, AD MacKerell Jr, A Melnick, F Xue Journal of medicinal chemistry 64 (8), 4333-4358, 2021 | 25 | 2021 |
| Design and synthesis of new hybrids from 2-cyano-3, 12-dioxooleana-9-dien-28-oic acid and O 2-(2, 4-dinitrophenyl) diazeniumdiolate for intervention of drug-resistant lung cancer F Kang, Y Ai, Y Zhang, Z Huang European Journal of Medicinal Chemistry 149, 269-280., 2018 | 23 | 2018 |
| Triazole-based inhibitors of the Wnt/β-Catenin signaling pathway improve glucose and lipid metabolisms in diet-induced obese mice ON Obianom, Y Ai, Y Li, W Yang, D Guo, H Yang, S Sakamuru, M Xia, ... Journal of medicinal chemistry 62 (2), 727-741, 2019 | 21 | 2019 |
| Molecular Modeling Studies on 11H-Dibenz[b,e]azepine and Dibenz[b,f][1,4]oxazepine Derivatives as Potent Agonists of the Human TRPA1 Receptor Y Ai, FJ Song, ST Wang, Q Sun, PH Sun Molecules 15 (12), 9364-9379, 2010 | 21 | 2010 |
| Novel cinnamaldehyde-based aspirin derivatives for the treatment of colorectal cancer S Lu, ON Obianom, Y Ai Bioorganic & medicinal chemistry letters 28 (17), 2869-2874, 2018 | 20 | 2018 |
| 3D-QSAR and docking studies on pyridopyrazinones as BRAF inhibitors Y Ai, ST Wang, C Tang, PH Sun, FJ Song Medicinal Chemistry Research 20, 1298-1317, 2011 | 20 | 2011 |
| Combined 3D-QSAR modeling and molecular docking studies on Pyrrole-Indolin-2-ones as Aurora A Kinase inhibitors Y Ai, ST Wang, PH Sun, FJ Song International Journal of Molecular Sciences 12 (3), 1605-1624, 2011 | 20 | 2011 |
Obinna N. ObianomJohnson and JohnsonVerifierad e-postadress på umaryland.edu