Senolytic CAR T cells reverse senescence-associated pathologies C Amor, J Feucht, J Leibold, YJ Ho, C Zhu, D Alonso-Curbelo, ... Nature 583 (7814), 127-132, 2020 | 775 | 2020 |
BRD4 connects enhancer remodeling to senescence immune surveillance N Tasdemir, A Banito, JS Roe, D Alonso-Curbelo, M Camiolo, ... Cancer discovery 6 (6), 612-629, 2016 | 371* | 2016 |
Senescence-induced vascular remodeling creates therapeutic vulnerabilities in pancreas cancer M Ruscetti, JP Morris, R Mezzadra, J Russell, J Leibold, PB Romesser, ... Cell 181 (2), 424-441. e21, 2020 | 315 | 2020 |
Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells D Tormo, A Chęcińska, D Alonso-Curbelo, E Pérez-Guijarro, E Cañón, ... Cancer cell 16 (2), 103-114, 2009 | 242 | 2009 |
A gene–environment-induced epigenetic program initiates tumorigenesis D Alonso-Curbelo, YJ Ho, C Burdziak, JLV Maag, JP Morris IV, ... Nature 590 (7847), 642-648, 2021 | 223 | 2021 |
Whole-body imaging of lymphovascular niches identifies pre-metastatic roles of midkine D Olmeda, D Cerezo-Wallis, E Riveiro-Falkenbach, PC Pennacchi, ... Nature 546 (7660), 676-680, 2017 | 165 | 2017 |
Altered RNA splicing by mutant p53 activates oncogenic RAS signaling in pancreatic cancer LF Escobar-Hoyos, A Penson, R Kannan, H Cho, CH Pan, RK Singh, ... Cancer cell 38 (2), 198-211. e8, 2020 | 153 | 2020 |
RAB7 controls melanoma progression by exploiting a lineage-specific wiring of the endolysosomal pathway D Alonso-Curbelo, E Riveiro-Falkenbach, E Pérez-Guijarro, M Cifdaloz, ... Cancer cell 26 (1), 61-76, 2014 | 121 | 2014 |
Senescence rewires microenvironment sensing to facilitate antitumor immunity HA Chen, YJ Ho, R Mezzadra, JM Adrover, R Smolkin, C Zhu, K Woess, ... Cancer discovery 13 (2), 432-453, 2023 | 114 | 2023 |
An In Vivo Kras Allelic Series Reveals Distinct Phenotypes of Common Oncogenic Variants MP Zafra, MJ Parsons, J Kim, D Alonso-Curbelo, S Goswami, EM Schatoff, ... Cancer discovery 10 (11), 1654-1671, 2020 | 112 | 2020 |
Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis C Burdziak, D Alonso-Curbelo, T Walle, J Reyes, FM Barriga, D Haviv, ... Science 380 (6645), eadd5327, 2023 | 100 | 2023 |
MACHETE identifies interferon-encompassing chromosome 9p21. 3 deletions as mediators of immune evasion and metastasis FM Barriga, KM Tsanov, YJ Ho, N Sohail, A Zhang, T Baslan, AN Wuest, ... Nature Cancer 3 (11), 1367-1385, 2022 | 80 | 2022 |
p62/SQSTM1 fuels melanoma progression by opposing mRNA decay of a selective set of pro-metastatic factors P Karras, E Riveiro-Falkenbach, E Cañón, C Tejedo, TG Calvo, ... Cancer Cell 35 (1), 46-63. e10, 2019 | 61 | 2019 |
Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers E Pérez-Guijarro, P Karras, M Cifdaloz, R Martínez-Herranz, E Cañón, ... Nature communications 7 (1), 13418, 2016 | 58 | 2016 |
Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity LWS Finley, SA Vardhana, BW Carey, D Alonso-Curbelo, R Koche, ... Nature cell biology 20 (5), 565-574, 2018 | 53 | 2018 |
Arid1a restrains Kras-dependent changes in acinar cell identity G Livshits, D Alonso-Curbelo, JP Morris IV, R Koche, M Saborowski, ... Elife 7, e35216, 2018 | 52 | 2018 |
Self-killing of melanoma cells by cytosolic delivery of dsRNA: wiring innate immunity for a coordinated mobilization of endosomes, autophagosomes and the apoptotic machinery in … D Alonso-Curbelo, MS Soengas Autophagy 6 (1), 148-150, 2010 | 31 | 2010 |
Chromatin-informed inference of transcriptional programs in gynecologic and basal breast cancers HU Osmanbeyoglu, F Shimizu, A Rynne-Vidal, D Alonso-Curbelo, ... Nature communications 10 (1), 4369, 2019 | 30 | 2019 |
RAB7 counteracts PI3K-driven macropinocytosis activated at early stages of melanoma development D Alonso-Curbelo, L Osterloh, E Canon, TG Calvo, R Martinez-Herranz, ... Oncotarget 6 (14), 11848, 2015 | 29 | 2015 |
Senescence-induced vascular remodeling creates therapeutic vulnerabilities in pancreas cancer M Ruscetti, JP Morris, R Mezzadra, J Russell, J Leibold, PB Romesser, ... Cell 184 (18), 4838-4839, 2021 | 25 | 2021 |