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yew ann leong
yew ann leong
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Circulating precursor CCR7loPD-1hi CXCR5+ CD4+ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure
J He, LM Tsai, YA Leong, X Hu, CS Ma, N Chevalier, X Sun, ...
Immunity 39 (4), 770-781, 2013
7082013
Low-dose interleukin-2 treatment selectively modulates CD4+ T cell subsets in patients with systemic lupus erythematosus
J He, X Zhang, Y Wei, X Sun, Y Chen, J Deng, Y Jin, Y Gan, X Hu, R Jia, ...
Nature medicine 22 (9), 991-993, 2016
5572016
CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles
YA Leong, Y Chen, HS Ong, D Wu, K Man, C Deleage, M Minnich, ...
Nature immunology 17 (10), 1187-1196, 2016
4832016
Energetic trade-offs and hypometabolic states promote disease tolerance
K Ganeshan, J Nikkanen, K Man, YA Leong, Y Sogawa, JA Maschek, ...
Cell 177 (2), 399-413. e12, 2019
2422019
PTPN2-deficiency exacerbates T follicular helper cell and B cell responses and promotes the development of autoimmunity
F Wiede, F Sacirbegovic, YA Leong, D Yu, T Tiganis
Journal of autoimmunity 76, 85-100, 2017
712017
Ndfip1-deficient mice have impaired DMT1 regulation and iron homeostasis
NJ Foot, YA Leong, LE Dorstyn, HE Dalton, K Ho, L Zhao, MD Garrick, ...
Blood, The Journal of the American Society of Hematology 117 (2), 638-646, 2011
482011
T-cell–specific PTPN2 deficiency in NOD mice accelerates the development of type 1 diabetes and autoimmune comorbidities
F Wiede, TC Brodnicki, PK Goh, YA Leong, GW Jones, D Yu, AG Baxter, ...
Diabetes 68 (6), 1251-1266, 2019
422019
Nutrient sensing in CD11c cells alters the gut microbiota to regulate food intake and body mass
DN Chagwedera, QY Ang, JE Bisanz, YA Leong, K Ganeshan, J Cai, ...
Cell metabolism 30 (2), 364-373. e7, 2019
372019
An evolutionary trade-off between host immunity and metabolism drives fatty liver in male mice
J Nikkanen, YA Leong, WC Krause, D Dermadi, JA Maschek, T Van Ry, ...
Science 378 (6617), 290-295, 2022
362022
Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation
Z Chen, Y Cui, Y Yao, B Liu, J Yunis, X Gao, N Wang, PF Cañete, ...
Science immunology 8 (80), eadd1728, 2023
312023
Human Immunodeficiency Virus Playing Hide-and-Seek: Understanding the TFH Cell Reservoir and Proposing Strategies to Overcome the Follicle Sanctuary
YA Leong, A Atnerkar, D Yu
Frontiers in Immunology 8, 622, 2017
172017
Efficient production of recombinant IL-21 proteins for pre-clinical studies by a two-step dilution refolding method
Z Chen, Y Cui, YA Leong, T Beddoe, D Yu
International Immunopharmacology 16 (3), 376-381, 2013
162013
AB0525 safety and efficiency of low-dose interleukin-2 treatment in systemic lupus erythematosus
J He, X Zhang, D Yu, ZG Li
Annals of the Rheumatic Diseases 74, 1075-1076, 2015
32015
Navigating double negatives: new pathways for regulating TFH differentiation
D Yu, Y Chen, YA Leong
Nature Immunology 15 (7), 597-599, 2014
32014
IL-2 enhances effector function but suppresses follicular localization of CD8+ T cells in chronic infection
Y Chen, P Zhou, PM Gubser, YA Leong, J He, Y Wei, FV Makota, ...
bioRxiv, 2024.05. 02.592184, 2024
2024
Trade-Offs Between Hepatic Host Defense and Metabolic Programs Underlie Sex-Biased Diseases
J Nikkanen, YA Leong, WC Krause, D Dermadi, JA Maschek, T Van Ry, ...
bioRxiv, 2022.01. 07.475423, 2022
2022
By Danai Nyasha Chagwedera
DN Chagwedera
2018
The role of the CD11c+ cells Tsc1-mTORC1 nutrient sensing pathway in metabolic homeostasis
DN Chagwedera
UCSF, 2018
2018
Interleukin-2 inhibits the differentiation of follicular cytotoxic CD8+ T cells during chronic viral infection
Y Chen, D Yu, YA Leong, Y Wei, H Ong, H Wang
CYTOKINE 100, 178-178, 2017
2017
Creating a super-cytokine: a structural perspective on the super-agonists of interluekin-21
Z Chen, Y Cui, Y Leong, D Littler, F Whightman, T Beddoe, J Rossjohn, ...
CYTOKINE 100, 108-108, 2017
2017
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Artiklar 1–20