Circulating precursor CCR7loPD-1hi CXCR5+ CD4+ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure J He, LM Tsai, YA Leong, X Hu, CS Ma, N Chevalier, X Sun, ... Immunity 39 (4), 770-781, 2013 | 708 | 2013 |
Low-dose interleukin-2 treatment selectively modulates CD4+ T cell subsets in patients with systemic lupus erythematosus J He, X Zhang, Y Wei, X Sun, Y Chen, J Deng, Y Jin, Y Gan, X Hu, R Jia, ... Nature medicine 22 (9), 991-993, 2016 | 557 | 2016 |
CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles YA Leong, Y Chen, HS Ong, D Wu, K Man, C Deleage, M Minnich, ... Nature immunology 17 (10), 1187-1196, 2016 | 483 | 2016 |
Energetic trade-offs and hypometabolic states promote disease tolerance K Ganeshan, J Nikkanen, K Man, YA Leong, Y Sogawa, JA Maschek, ... Cell 177 (2), 399-413. e12, 2019 | 242 | 2019 |
PTPN2-deficiency exacerbates T follicular helper cell and B cell responses and promotes the development of autoimmunity F Wiede, F Sacirbegovic, YA Leong, D Yu, T Tiganis Journal of autoimmunity 76, 85-100, 2017 | 71 | 2017 |
Ndfip1-deficient mice have impaired DMT1 regulation and iron homeostasis NJ Foot, YA Leong, LE Dorstyn, HE Dalton, K Ho, L Zhao, MD Garrick, ... Blood, The Journal of the American Society of Hematology 117 (2), 638-646, 2011 | 48 | 2011 |
T-cell–specific PTPN2 deficiency in NOD mice accelerates the development of type 1 diabetes and autoimmune comorbidities F Wiede, TC Brodnicki, PK Goh, YA Leong, GW Jones, D Yu, AG Baxter, ... Diabetes 68 (6), 1251-1266, 2019 | 42 | 2019 |
Nutrient sensing in CD11c cells alters the gut microbiota to regulate food intake and body mass DN Chagwedera, QY Ang, JE Bisanz, YA Leong, K Ganeshan, J Cai, ... Cell metabolism 30 (2), 364-373. e7, 2019 | 37 | 2019 |
An evolutionary trade-off between host immunity and metabolism drives fatty liver in male mice J Nikkanen, YA Leong, WC Krause, D Dermadi, JA Maschek, T Van Ry, ... Science 378 (6617), 290-295, 2022 | 36 | 2022 |
Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation Z Chen, Y Cui, Y Yao, B Liu, J Yunis, X Gao, N Wang, PF Cañete, ... Science immunology 8 (80), eadd1728, 2023 | 31 | 2023 |
Human Immunodeficiency Virus Playing Hide-and-Seek: Understanding the TFH Cell Reservoir and Proposing Strategies to Overcome the Follicle Sanctuary YA Leong, A Atnerkar, D Yu Frontiers in Immunology 8, 622, 2017 | 17 | 2017 |
Efficient production of recombinant IL-21 proteins for pre-clinical studies by a two-step dilution refolding method Z Chen, Y Cui, YA Leong, T Beddoe, D Yu International Immunopharmacology 16 (3), 376-381, 2013 | 16 | 2013 |
AB0525 safety and efficiency of low-dose interleukin-2 treatment in systemic lupus erythematosus J He, X Zhang, D Yu, ZG Li Annals of the Rheumatic Diseases 74, 1075-1076, 2015 | 3 | 2015 |
Navigating double negatives: new pathways for regulating TFH differentiation D Yu, Y Chen, YA Leong Nature Immunology 15 (7), 597-599, 2014 | 3 | 2014 |
IL-2 enhances effector function but suppresses follicular localization of CD8+ T cells in chronic infection Y Chen, P Zhou, PM Gubser, YA Leong, J He, Y Wei, FV Makota, ... bioRxiv, 2024.05. 02.592184, 2024 | | 2024 |
Trade-Offs Between Hepatic Host Defense and Metabolic Programs Underlie Sex-Biased Diseases J Nikkanen, YA Leong, WC Krause, D Dermadi, JA Maschek, T Van Ry, ... bioRxiv, 2022.01. 07.475423, 2022 | | 2022 |
By Danai Nyasha Chagwedera DN Chagwedera | | 2018 |
The role of the CD11c+ cells Tsc1-mTORC1 nutrient sensing pathway in metabolic homeostasis DN Chagwedera UCSF, 2018 | | 2018 |
Interleukin-2 inhibits the differentiation of follicular cytotoxic CD8+ T cells during chronic viral infection Y Chen, D Yu, YA Leong, Y Wei, H Ong, H Wang CYTOKINE 100, 178-178, 2017 | | 2017 |
Creating a super-cytokine: a structural perspective on the super-agonists of interluekin-21 Z Chen, Y Cui, Y Leong, D Littler, F Whightman, T Beddoe, J Rossjohn, ... CYTOKINE 100, 108-108, 2017 | | 2017 |