| p53 is a direct transcriptional target of MYCN in neuroblastoma L Chen, N Iraci, S Gherardi, LD Gamble, KM Wood, G Perini, J Lunec, ... Cancer research 70 (4), 1377-1388, 2010 | 182 | 2010 |
| Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma DR Carter, J Murray, BB Cheung, L Gamble, J Koach, J Tsang, S Sutton, ... Science translational medicine 7 (312), 312ra176-312ra176, 2015 | 141 | 2015 |
| Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma LD Gamble, S Purgato, J Murray, L Xiao, DMT Yu, KM Hanssen, ... Science Translational Medicine 11 (477), eaau1099, 2019 | 127 | 2019 |
| Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas A Khan, LD Gamble, DH Upton, C Ung, DMT Yu, A Ehteda, R Pandher, ... Nature communications 12 (1), 971, 2021 | 100 | 2021 |
| MYCN sensitizes neuroblastoma to the MDM2-p53 antagonists Nutlin-3 and MI-63 LD Gamble, UR Kees, DA Tweddle, J Lunec Oncogene 31 (6), 752-763, 2012 | 98 | 2012 |
| Polyamine antagonist therapies inhibit neuroblastoma initiation and progression NF Evageliou, M Haber, A Vu, TW Laetsch, J Murray, LD Gamble, ... Clinical Cancer Research 22 (17), 4391-4404, 2016 | 87 | 2016 |
| Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma LD Gamble, MD Hogarty, X Liu, DS Ziegler, G Marshall, MD Norris, ... Frontiers in oncology 2, 162, 2012 | 72 | 2012 |
| Macrophage-derived IL1β and TNFα regulate arginine metabolism in neuroblastoma L Fultang, LD Gamble, L Gneo, AM Berry, SA Egan, F De Bie, O Yogev, ... Cancer research 79 (3), 611-624, 2019 | 60 | 2019 |
| Living alone with mild-to-moderate dementia: Findings from the IDEAL cohort L Clare, A Martyr, C Henderson, L Gamble, FE Matthews, C Quinn, ... Journal of Alzheimer’s Disease 78 (3), 1207-1216, 2020 | 40 | 2020 |
| Suppression of the ATP-binding cassette transporter ABCC4 impairs neuroblastoma tumour growth and sensitises to irinotecan in vivo J Murray, E Valli, MT Denise, AM Truong, AJ Gifford, GL Eden, LD Gamble, ... European Journal of Cancer 83, 132-141, 2017 | 34 | 2017 |
| Targeting metabolic activity in high-risk neuroblastoma through Monocarboxylate Transporter 1 (MCT1) inhibition A Khan, E Valli, H Lam, DA Scott, J Murray, KM Hanssen, G Eden, ... Oncogene 39 (17), 3555-3570, 2020 | 33 | 2020 |
| Impact of COVID-19 on ‘living well’with mild-to-moderate dementia in the community: findings from the IDEAL cohort L Clare, A Martyr, LD Gamble, C Pentecost, R Collins, E Dawson, A Hunt, ... Journal of Alzheimer’s Disease 85 (2), 925-940, 2022 | 28 | 2022 |
| Dual targeting of chromatin stability by the curaxin CBL0137 and histone deacetylase inhibitor panobinostat shows significant preclinical efficacy in neuroblastoma L Xiao, K Somers, J Murray, R Pandher, M Karsa, E Ronca, A Bongers, ... Clinical Cancer Research 27 (15), 4338-4352, 2021 | 27 | 2021 |
| MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4 C Xue, MT Denise, S Gherardi, J Koach, G Milazzo, L Gamble, B Liu, ... Oncotarget 7 (34), 54937, 2016 | 27 | 2016 |
| Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial O Abani, A Abbas, F Abbas, J Abbas, K Abbas, M Abbas, S Abbasi, ... The lancet Diabetes & endocrinology 11 (12), 905-914, 2023 | 24 | 2023 |
| Characteristics of people living with undiagnosed dementia: findings from the CFAS Wales study LD Gamble, FE Matthews, IR Jones, AE Hillman, B Woods, CA Macleod, ... BMC geriatrics 22 (1), 409, 2022 | 21 | 2022 |
| What are the benefits of pet ownership and care among people with mild-to-moderate dementia? Findings from the IDEAL programme C Opdebeeck, MA Katsaris, A Martyr, RA Lamont, JA Pickett, I Rippon, ... Journal of Applied Gerontology 40 (11), 1559-1567, 2021 | 21 | 2021 |
| Outcome of the p53-mediated DNA damage response in neuroblastoma is determined by morphological subtype and MYCN expression J Carr-Wilkinson, R Griffiths, R Elston, LD Gamble, B Goranov, ... Cell Cycle 10 (21), 3778-3787, 2011 | 18 | 2011 |
| Longitudinal trajectories of quality of life among people with mild-to-moderate dementia: a latent growth model approach with IDEAL cohort study data L Clare, LD Gamble, A Martyr, S Sabatini, SM Nelis, C Quinn, C Pentecost, ... The Journals of Gerontology: Series B 77 (6), 1037-1050, 2022 | 16 | 2022 |
| “Living Well” trajectories among family caregivers of people with mild-to-moderate dementia in the IDEAL Cohort L Clare, LD Gamble, A Martyr, S Sabatini, SM Nelis, C Quinn, C Pentecost, ... The Journals of Gerontology: Series B 77 (10), 1852-1863, 2022 | 15 | 2022 |
