Integrated Genomic Analyses of Ovarian Carcinoma Nature 474 (7353), 609-615, 2011 | 7220 | 2011 |
Perturbations of the AKT signaling pathway in human cancer DA Altomare, JR Testa Oncogene 24 (50), 7455-7464, 2005 | 1661 | 2005 |
A Retroviral Oncogene, akt, Encoding a Serine-Threonine Kinase Containing an SH2-Like Region A Bellacosa, JR Testa, SP Staal, PN Tsichlis Science 254 (5029), 274-277, 1991 | 1375 | 1991 |
AKT plays a central role in tumorigenesis JR Testa, A Bellacosa Proceedings of the National Academy of Sciences 98 (20), 10983-10985, 2001 | 1256 | 2001 |
Germline BAP1 mutations predispose to malignant mesothelioma JR Testa, M Cheung, J Pei, JE Below, Y Tan, E Sementino, NJ Cox, ... Nature genetics 43 (10), 1022-1025, 2011 | 1242 | 2011 |
Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas A Bellacosa, D De Feo, AK Godwin, DW Bell, JQ Cheng, DA Altomare, ... International journal of cancer 64 (4), 280-285, 1995 | 1171 | 1995 |
Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA. JQ Cheng, B Ruggeri, WM Klein, G Sonoda, DA Altomare, DK Watson, ... Proceedings of the National Academy of Sciences 93 (8), 3636-3641, 1996 | 1081 | 1996 |
Activation of AKT kinases in cancer: implications for therapeutic targeting A Bellacosa, CC Kumar, A Di Cristofano, JR Testa Advances in cancer research 94, 29-86, 2005 | 1044 | 2005 |
AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas. JQ Cheng, AK Godwin, A Bellacosa, T Taguchi, TF Franke, TC Hamilton, ... Proceedings of the National Academy of Sciences 89 (19), 9267-9271, 1992 | 1004 | 1992 |
BAP1 and cancer M Carbone, H Yang, HI Pass, T Krausz, JR Testa, G Gaudino Nature Reviews Cancer 13 (3), 153-159, 2013 | 740 | 2013 |
Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E AC Hsieh, M Costa, O Zollo, C Davis, ME Feldman, JR Testa, O Meyuhas, ... Cancer cell 17 (3), 249-261, 2010 | 555 | 2010 |
Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways GH Xiao, M Jeffers, A Bellacosa, Y Mitsuuchi, GF Vande Woude, JR Testa Proceedings of the National Academy of Sciences 98 (1), 247-252, 2001 | 525 | 2001 |
The pathogenesis of mesothelioma M Carbone, RA Kratzke, JR Testa Seminars in oncology 29 (1), 2-17, 2002 | 505 | 2002 |
AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth DA Altomare, HQ Wang, KL Skele, AD Rienzo, AJ Klein-Szanto, ... Oncogene 23 (34), 5853-5857, 2004 | 503 | 2004 |
p16 Alterations and Deletion Mapping of 9p21–p22 in Malignant Mesothelioma JQ Cheng, SC Jhanwar, WM Klein, DW Bell, WC Lee, DA Altomare, ... Cancer research 54 (21), 5547-5551, 1994 | 445 | 1994 |
High frequency of inactivating mutations in the neurofibromatosis type 2 gene (NF2) in primary malignant mesotheliomas. AB Bianchi, SI Mitsunaga, JQ Cheng, WM Klein, SC Jhanwar, B Seizinger, ... Proceedings of the National Academy of Sciences 92 (24), 10854-10858, 1995 | 440 | 1995 |
Amplification and overexpression of the AKT2 oncogene in a subset of human pancreatic ductal adenocarcinomas BA Ruggeri, L Huang, M Wood, JQ Cheng, JR Testa Molecular Carcinogenesis: Published in cooperation with the University of …, 1998 | 432 | 1998 |
p53 Mutations, ras Mutations, and p53-Heat Shock 70 Protein Complexes in Human Lung Carcinoma Cell Lines TA Lehman, WP Bennett, RA Metcalf, JA Welsh, J Ecker, RV Modali, ... Cancer research 51 (15), 4090-4096, 1991 | 407 | 1991 |
TNF-α inhibits asbestos-induced cytotoxicity via a NF-κB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis H Yang, M Bocchetta, B Kroczynska, AG Elmishad, Y Chen, Z Liu, ... Proceedings of the National Academy of Sciences 103 (27), 10397-10402, 2006 | 392 | 2006 |
Frequent activation of AKT in non-small cell lung carcinomas and preneoplastic bronchial lesions BR Balsara, J Pei, Y Mitsuuchi, R Page, A Klein-Szanto, H Wang, ... Carcinogenesis 25 (11), 2053-2059, 2004 | 371 | 2004 |