| α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson’s disease R Di Maio, PJ Barrett, EK Hoffman, CW Barrett, A Zharikov, A Borah, X Hu, ... Science translational medicine 8 (342), 342ra78-342ra78, 2016 | 667 | 2016 |
| LRRK2 activation in idiopathic Parkinson’s disease R Di Maio, EK Hoffman, EM Rocha, MT Keeney, LH Sanders, ... Science translational medicine 10 (451), eaar5429, 2018 | 493 | 2018 |
| Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization VS Van Laar, B Arnold, SJ Cassady, CT Chu, EA Burton, SB Berman Human molecular genetics 20 (5), 927-940, 2011 | 261 | 2011 |
| shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson’s disease model AD Zharikov, JR Cannon, V Tapias, Q Bai, MP Horowitz, V Shah, ... The Journal of clinical investigation 125 (7), 2721-2735, 2015 | 197 | 2015 |
| Herpes simplex virus RNAi and neprilysin gene transfer vectors reduce accumulation of Alzheimer's disease-related amyloid-β peptide in vivo CS Hong, WF Goins, JR Goss, EA Burton, JC Glorioso Gene therapy 13 (14), 1068-1079, 2006 | 164 | 2006 |
| Induction of utrophin gene expression by heregulin in skeletal muscle cells: role of the N-box motif and GA binding protein AO Gramolini, LM Angus, L Schaeffer, EA Burton, JM Tinsley, KE Davies, ... Proceedings of the National Academy of Sciences 96 (6), 3223-3227, 1999 | 164 | 1999 |
| Genetic zebrafish models of neurodegenerative diseases O Bandmann, EA Burton Neurobiology of disease 40 (1), 58-65, 2010 | 160 | 2010 |
| A-and B-utrophin have different expression patterns and are differentially up-regulated in mdx muscle AP Weir, EA Burton, G Harrod, KE Davies Journal of Biological Chemistry 277 (47), 45285-45290, 2002 | 145 | 2002 |
| Gene delivery using herpes simplex virus vectors EA Burton, DJ Fink, JC Glorioso DNA and cell biology 21 (12), 915-936, 2002 | 140 | 2002 |
| Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation … M Keatinge, H Bui, A Menke, YC Chen, AM Sokol, Q Bai, F Ellett, ... Human molecular genetics 24 (23), 6640-6652, 2015 | 136 | 2015 |
| A second promoter provides an alternative target for therapeutic up-regulation of utrophin in Duchenne muscular dystrophy EA Burton, JM Tinsley, PJ Holzfeind, NR Rodrigues, KE Davies Proceedings of the National Academy of Sciences 96 (24), 14025-14030, 1999 | 131 | 1999 |
| Generation of a transgenic zebrafish model of Tauopathy using a novel promoter element derived from the zebrafish eno2 gene Q Bai, JA Garver, NA Hukriede, EA Burton Nucleic acids research 35 (19), 6501-6516, 2007 | 129 | 2007 |
| Research on the premotor symptoms of Parkinson’s disease: clinical and etiological implications H Chen, EA Burton, GW Ross, X Huang, R Savica, RD Abbott, A Ascherio, ... Environmental health perspectives 121 (11-12), 1245-1252, 2013 | 123 | 2013 |
| Transgenic zebrafish models of neurodegenerative diseases JJ Sager, Q Bai, EA Burton Brain Structure and Function 214, 285-302, 2010 | 123 | 2010 |
| HSV trafficking and development of gene therapy vectors with applications in the nervous system AR Frampton, WF Goins, K Nakano, EA Burton, JC Glorioso Gene therapy 12 (11), 891-901, 2005 | 120 | 2005 |
| Astrocyte-specific DJ-1 overexpression protects against rotenone-induced neurotoxicity in a rat model of Parkinson's disease BR De Miranda, EM Rocha, Q Bai, A El Ayadi, D Hinkle, EA Burton, ... Neurobiology of disease 115, 101-114, 2018 | 104 | 2018 |
| Gene therapy progress and prospects: Parkinson's disease EA Burton, JC Glorioso, DJ Fink Gene Therapy 10 (20), 1721-1727, 2003 | 104 | 2003 |
| Muscle and neural isoforms of agrin increase utrophin expression in cultured myotubes via a transcriptional regulatory mechanism AO Gramolini, EA Burton, JM Tinsley, MJ Ferns, A Cartaud, J Cartaud, ... Journal of Biological Chemistry 273 (2), 736-743, 1998 | 104 | 1998 |
| Multiple applications for replication-defective herpes simplex virus vectors EA Burton, JB Wechuck, SK Wendell, WF Goins, DJ Fink, JC Glorioso Stem Cells 19 (5), 358-377, 2001 | 101 | 2001 |
| Claudin k is specifically expressed in cells that form myelin during development of the nervous system and regeneration of the optic nerve in adult zebrafish EJ Münzel, K Schaefer, B Obirei, E Kremmer, EA Burton, V Kuscha, ... Glia 60 (2), 253-270, 2012 | 97 | 2012 |
J Timothy GreenamyreDirector, Pittsburgh Institute for Neurodegenerative Diseases, Professor of NeurologyVerifierad e-postadress på pitt.edu