| A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression CA Zarate, JB Singh, PJ Carlson, NE Brutsche, R Ameli, DA Luckenbaugh, ... Archives of general psychiatry 63 (8), 856-864, 2006 | 4162 | 2006 |
| NMDAR inhibition-independent antidepressant actions of ketamine metabolites P Zanos, R Moaddel, PJ Morris, P Georgiou, J Fischell, GI Elmer, ... Nature 533 (7604), 481-486, 2016 | 1605 | 2016 |
| Cellular mechanisms underlying the antidepressant effects of ketamine: role of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors S Maeng, CA Zarate Jr, J Du, RJ Schloesser, J McCammon, G Chen, ... Biological psychiatry 63 (4), 349-352, 2008 | 1293 | 2008 |
| Ketamine and ketamine metabolite pharmacology: insights into therapeutic mechanisms P Zanos, R Moaddel, PJ Morris, LM Riggs, JN Highland, P Georgiou, ... Pharmacological reviews 70 (3), 621-660, 2018 | 1161 | 2018 |
| A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression N Diazgranados, L Ibrahim, NE Brutsche, A Newberg, P Kronstein, ... Archives of general psychiatry 67 (8), 793-802, 2010 | 1161 | 2010 |
| Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders G Sanacora, CA Zarate, JH Krystal, HK Manji Nature reviews Drug discovery 7 (5), 426-437, 2008 | 1120 | 2008 |
| Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled add-on trial CA Zarate Jr, NE Brutsche, L Ibrahim, J Franco-Chaves, N Diazgranados, ... Biological psychiatry 71 (11), 939-946, 2012 | 934 | 2012 |
| The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders I Pacchiarotti, DJ Bond, RJ Baldessarini, WA Nolen, H Grunze, RW Licht, ... American Journal of Psychiatry 170 (11), 1249-1262, 2013 | 828 | 2013 |
| Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group DP Hibar, LT Westlye, NT Doan, N Jahanshad, JW Cheung, CRK Ching, ... Molecular psychiatry 23 (4), 932-942, 2018 | 751 | 2018 |
| Rapid resolution of suicidal ideation after a single infusion of an N-methyl-D-aspartate antagonist in patients with treatment-resistant major depressive disorder N DiazGranados, LA Ibrahim, NE Brutsche, R Ameli, ID Henter, ... The Journal of clinical psychiatry 71 (12), 16899, 2010 | 712 | 2010 |
| The effect of a single dose of intravenous ketamine on suicidal ideation: a systematic review and individual participant data meta-analysis ST Wilkinson, ED Ballard, MH Bloch, SJ Mathew, JW Murrough, A Feder, ... American journal of psychiatry 175 (2), 150-158, 2018 | 692 | 2018 |
| Two-year syndromal and functional recovery in 219 cases of first-episode major affective disorder with psychotic features M Tohen, J Hennen, CM Zarate Jr, RJ Baldessarini, SM Strakowski, ... American Journal of Psychiatry 157 (2), 220-228, 2000 | 660 | 2000 |
| Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression HK Manji, JA Quiroz, J Sporn, JL Payne, K Denicoff, NA Gray, ... Biological psychiatry 53 (8), 707-742, 2003 | 655 | 2003 |
| The McLean-Harvard first-episode mania study: prediction of recovery and first recurrence M Tohen, CA Zarate Jr, J Hennen, HMK Khalsa, SM Strakowski, ... American Journal of Psychiatry 160 (12), 2099-2107, 2003 | 648 | 2003 |
| Efficacy of olanzapine in combination with valproate or lithium in the treatment of mania in patients partially nonresponsive to valproate or lithium monotherapy M Tohen, KNR Chengappa, T Suppes, CA Zarate, JR Calabrese, ... Archives of general psychiatry 59 (1), 62-69, 2002 | 643 | 2002 |
| Protocolized sedation vs usual care in pediatric patients mechanically ventilated for acute respiratory failure: a randomized clinical trial MAQ Curley, D Wypij, RS Watson, MJC Grant, LA Asaro, IM Cheifetz, ... Jama 313 (4), 379-389, 2015 | 582* | 2015 |
| Synthesizing the evidence for ketamine and esketamine in treatment-resistant depression: an international expert opinion on the available evidence and implementation RS McIntyre, JD Rosenblat, CB Nemeroff, G Sanacora, JW Murrough, ... American Journal of Psychiatry 178 (5), 383-399, 2021 | 524 | 2021 |
| Depression in the primary care setting LT Park, CA Zarate Jr New England Journal of Medicine 380 (6), 559-568, 2019 | 510 | 2019 |
| International Society for Bipolar Disorders Task Force on Suicide: meta‐analyses and meta‐regression of correlates of suicide attempts and suicide deaths in bipolar disorder A Schaffer, ET Isometsä, L Tondo, D H Moreno, G Turecki, C Reis, ... Bipolar disorders 17 (1), 1-16, 2015 | 503 | 2015 |
| A double-blind, placebo-controlled study of memantine in the treatment of major depression CA Zarate Jr, JB Singh, JA Quiroz, G De Jesus, KK Denicoff, ... American Journal of Psychiatry 163 (1), 153-155, 2006 | 480 | 2006 |