Fighting antibiotic resistance—strategies and (pre) clinical developments to find new antibacterials S Walesch, J Birkelbach, G Jézéquel, FPJ Haeckl, JD Hegemann, ... EMBO reports 24 (1), e56033, 2023 | 131 | 2023 |
Cytotoxic Prenylated Stilbenes Isolated from Macaranga tanarius T Péresse, G Jézéquel, PM Allard, VC Pham, DTM Huong, F Blanchard, ... Journal of natural products 80 (10), 2684-2691, 2017 | 59 | 2017 |
Structure-Based Design of α-Substituted Mercaptoacetamides as Inhibitors of the Virulence Factor LasB from Pseudomonas aeruginosa C Kaya, I Walter, A Alhayek, R Shafiei, G Jézéquel, A Andreas, ... ACS Infectious Diseases 8 (5), 1010-1021, 2022 | 16 | 2022 |
The Structures and Binding Modes of Small-Molecule Inhibitors of Pseudomonas aeruginosa Elastase LasB V Camberlein, G Jézéquel, J Haupenthal, AKH Hirsch Antibiotics 11 (8), 1060, 2022 | 12 | 2022 |
Structure-Based Design of a Lead Compound Derived from Natural Schweinfurthins with Antitumor Properties That Target Oxysterol-Binding Protein G Jézéquel, C Rampal, C Guimard, D Kovacs, J Polidori, J Bigay, ... Journal of Medicinal Chemistry 66 (20), 14208-14220, 2023 | 9 | 2023 |
Synthesis and anti-leishmanial properties of quinolones derived from zanthosimuline G Jézéquel, LNF Cardoso, F Olivon, I Dennemont, C Apel, M Litaudon, ... Molecules 27 (22), 7892, 2022 | 3 | 2022 |
Target-Directed Dynamic Combinatorial Chemistry Affords Binders of Mycobacterium tuberculosis IspE M Braun-Cornejo, C Ornago, V Sonawane, J Haupenthal, AM Kany, ... ACS omega 9 (36), 38160-38168, 2024 | 1 | 2024 |
Functionalization of Chlorotonils: Dehalogenil as Promising Lead Compound for In Vivo Application W Hofer, F Deschner, G Jézéquel, L Pessanha de Carvalho, ... Angewandte Chemie International Edition 63 (19), e202319765, 2024 | 1 | 2024 |
Dynamic Combinatorial Chemistry Unveils Nsp10 Inhibitors with Antiviral Potential Against SARS‐CoV‐2 RP Jumde, G Jézéquel, M Saramago, N Frank, S Adam, MV Cunha, ... Chemistry–A European Journal 31 (4), e202403390, 2025 | | 2025 |
Analogues of Natural Macarangin B Display Potent Antiviral Activity and Better Metabolic Stability G Jézéquel, J Fargier, J Bigay, J Polidori, J Geslin, N Hue, ... | | 2024 |
Compound of the 7a, 8, 9, 10, 11, 11a-hexahydro-1H, 7H-pyrano [2, 3-c] xanthene type, method of preparation thereof, intermediates thereof and therapeutic applications thereof F Roussi, S Desrat, G Jezequel, J Bignon, M Litaudon, B Antonny, J Bigay, ... US Patent App. 18/577,572, 2024 | | 2024 |
Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function G Jézéquel, Z Grimanelli, C Guimard, J Bigay, J Haddad, J Bignon, ... Journal of Medicinal Chemistry 68 (1), 196-211, 2024 | | 2024 |
Re-exploring the salicylanilide scaffold for the inhibition of mycolic acid synthesis in Mycobacterium tuberculosis G Jézéquel, SA Taleb, C Mehalla, NH Le, M Muipata-Muabilua, V Guillet, ... Tackling antibacterial and antifungal resistant infections from disease to …, 2024 | | 2024 |
Process for the biobased synthesis of schweinfurthins g, k and r F Roussi, M Litaudon, S Desrat, G Jezequel, C Rampal, VC Pham, ... US Patent App. 18/575,408, 2024 | | 2024 |
Funktionalisierung von Chlorotonilen: Dehalogenil als vielversprechende Leitverbindung für die in vivo‐Anwendung W Hofer, F Deschner, G Jézéquel, L Pessanha de Carvalho, ... Angewandte Chemie 136 (19), e202319765, 2024 | | 2024 |
Bio-inspired synthesis and profiling of a potent antiviral flavonol targeting the lipid exchanger OSBP G Jézéquel, Z Grimanelli, C Guimard, J Bigay, J Haddad, J Bignon, ... | | 2024 |
Target-directed dynamic combinatorial chemistry affords inhibitors of Nsp10 as potential antivirals against SARS-CoV-2 RP Jumde, G Jézéquel, M Saramago, N Frank, S Adam, MV Cunha, ... | | 2023 |
Process for the biobased synthesis of schweinfurthins G, K and R M Litaudon, F Roussi, S Desrat, G Jézéquel, C Rampal, HDT Mai | | 2023 |
Efficient synthetic strategy to access analogues of an original natural bioactive flavone C Guimard, G Jézéquel, L Askenatzis, B Mesmin, J Bignon, S Desrat, ... Journées de Chimie Organique (JCO) 2022, 2022 | | 2022 |
Targeting OSBP degradation by PROTACs derived from schweinfurthin for cancer therapy C Guimard, G Jézéquel, L Askenatzis, J Bignon, S Desrat, F Roussi 27th EFMC International Symposium on Medicinal Chemistry, 2022 | | 2022 |