Följ
Gwenaëlle Jézéquel
Gwenaëlle Jézéquel
Postdoc at Helmholtz Institute, Saarbrücken
Verifierad e-postadress på helmholtz-hips.de
Titel
Citeras av
Citeras av
År
Fighting antibiotic resistance—strategies and (pre) clinical developments to find new antibacterials
S Walesch, J Birkelbach, G Jézéquel, FPJ Haeckl, JD Hegemann, ...
EMBO reports 24 (1), e56033, 2023
1312023
Cytotoxic Prenylated Stilbenes Isolated from Macaranga tanarius
T Péresse, G Jézéquel, PM Allard, VC Pham, DTM Huong, F Blanchard, ...
Journal of natural products 80 (10), 2684-2691, 2017
592017
Structure-Based Design of α-Substituted Mercaptoacetamides as Inhibitors of the Virulence Factor LasB from Pseudomonas aeruginosa
C Kaya, I Walter, A Alhayek, R Shafiei, G Jézéquel, A Andreas, ...
ACS Infectious Diseases 8 (5), 1010-1021, 2022
162022
The Structures and Binding Modes of Small-Molecule Inhibitors of Pseudomonas aeruginosa Elastase LasB
V Camberlein, G Jézéquel, J Haupenthal, AKH Hirsch
Antibiotics 11 (8), 1060, 2022
122022
Structure-Based Design of a Lead Compound Derived from Natural Schweinfurthins with Antitumor Properties That Target Oxysterol-Binding Protein
G Jézéquel, C Rampal, C Guimard, D Kovacs, J Polidori, J Bigay, ...
Journal of Medicinal Chemistry 66 (20), 14208-14220, 2023
92023
Synthesis and anti-leishmanial properties of quinolones derived from zanthosimuline
G Jézéquel, LNF Cardoso, F Olivon, I Dennemont, C Apel, M Litaudon, ...
Molecules 27 (22), 7892, 2022
32022
Target-Directed Dynamic Combinatorial Chemistry Affords Binders of Mycobacterium tuberculosis IspE
M Braun-Cornejo, C Ornago, V Sonawane, J Haupenthal, AM Kany, ...
ACS omega 9 (36), 38160-38168, 2024
12024
Functionalization of Chlorotonils: Dehalogenil as Promising Lead Compound for In Vivo Application
W Hofer, F Deschner, G Jézéquel, L Pessanha de Carvalho, ...
Angewandte Chemie International Edition 63 (19), e202319765, 2024
12024
Dynamic Combinatorial Chemistry Unveils Nsp10 Inhibitors with Antiviral Potential Against SARS‐CoV‐2
RP Jumde, G Jézéquel, M Saramago, N Frank, S Adam, MV Cunha, ...
Chemistry–A European Journal 31 (4), e202403390, 2025
2025
Analogues of Natural Macarangin B Display Potent Antiviral Activity and Better Metabolic Stability
G Jézéquel, J Fargier, J Bigay, J Polidori, J Geslin, N Hue, ...
2024
Compound of the 7a, 8, 9, 10, 11, 11a-hexahydro-1H, 7H-pyrano [2, 3-c] xanthene type, method of preparation thereof, intermediates thereof and therapeutic applications thereof
F Roussi, S Desrat, G Jezequel, J Bignon, M Litaudon, B Antonny, J Bigay, ...
US Patent App. 18/577,572, 2024
2024
Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function
G Jézéquel, Z Grimanelli, C Guimard, J Bigay, J Haddad, J Bignon, ...
Journal of Medicinal Chemistry 68 (1), 196-211, 2024
2024
Re-exploring the salicylanilide scaffold for the inhibition of mycolic acid synthesis in Mycobacterium tuberculosis
G Jézéquel, SA Taleb, C Mehalla, NH Le, M Muipata-Muabilua, V Guillet, ...
Tackling antibacterial and antifungal resistant infections from disease to …, 2024
2024
Process for the biobased synthesis of schweinfurthins g, k and r
F Roussi, M Litaudon, S Desrat, G Jezequel, C Rampal, VC Pham, ...
US Patent App. 18/575,408, 2024
2024
Funktionalisierung von Chlorotonilen: Dehalogenil als vielversprechende Leitverbindung für die in vivo‐Anwendung
W Hofer, F Deschner, G Jézéquel, L Pessanha de Carvalho, ...
Angewandte Chemie 136 (19), e202319765, 2024
2024
Bio-inspired synthesis and profiling of a potent antiviral flavonol targeting the lipid exchanger OSBP
G Jézéquel, Z Grimanelli, C Guimard, J Bigay, J Haddad, J Bignon, ...
2024
Target-directed dynamic combinatorial chemistry affords inhibitors of Nsp10 as potential antivirals against SARS-CoV-2
RP Jumde, G Jézéquel, M Saramago, N Frank, S Adam, MV Cunha, ...
2023
Process for the biobased synthesis of schweinfurthins G, K and R
M Litaudon, F Roussi, S Desrat, G Jézéquel, C Rampal, HDT Mai
2023
Efficient synthetic strategy to access analogues of an original natural bioactive flavone
C Guimard, G Jézéquel, L Askenatzis, B Mesmin, J Bignon, S Desrat, ...
Journées de Chimie Organique (JCO) 2022, 2022
2022
Targeting OSBP degradation by PROTACs derived from schweinfurthin for cancer therapy
C Guimard, G Jézéquel, L Askenatzis, J Bignon, S Desrat, F Roussi
27th EFMC International Symposium on Medicinal Chemistry, 2022
2022
Systemet kan inte utföra åtgärden just nu. Försök igen senare.
Artiklar 1–20