A mechanism linking extra centrosomes to chromosomal instability NJ Ganem, SA Godinho, D Pellman Nature 460 (7252), 278-282, 2009 | 1638 | 2009 |
DNA breaks and chromosome pulverization from errors in mitosis K Crasta, NJ Ganem, R Dagher, AB Lantermann, EV Ivanova, Y Pan, ... Nature 482 (7383), 53-58, 2012 | 1370 | 2012 |
Tetraploidy, aneuploidy and cancer NJ Ganem, Z Storchova, D Pellman Current opinion in genetics & development 17 (2), 157-162, 2007 | 845 | 2007 |
Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes M Kwon, SA Godinho, NS Chandhok, NJ Ganem, A Azioune, M Thery, ... Genes & development 22 (16), 2189-2203, 2008 | 749 | 2008 |
Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors RL Flynn, KE Cox, M Jeitany, H Wakimoto, AR Bryll, NJ Ganem, F Bersani, ... Science 347 (6219), 273-277, 2015 | 545 | 2015 |
Cytokinesis failure triggers hippo tumor suppressor pathway activation NJ Ganem, H Cornils, SY Chiu, KP O’Rourke, J Arnaud, D Yimlamai, ... Cell 158 (4), 833-848, 2014 | 411 | 2014 |
The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK NJ Ganem, DA Compton The Journal of cell biology 166 (4), 473-478, 2004 | 278 | 2004 |
The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells AL Manning, NJ Ganem, SF Bakhoum, M Wagenbach, L Wordeman, ... Molecular biology of the cell 18 (8), 2970-2979, 2007 | 270 | 2007 |
Linking abnormal mitosis to the acquisition of DNA damage NJ Ganem, D Pellman Journal of Cell Biology 199 (6), 871-881, 2012 | 260 | 2012 |
Efficient mitosis in human cells lacking poleward microtubule flux NJ Ganem, K Upton, DA Compton Current biology 15 (20), 1827-1832, 2005 | 252 | 2005 |
Mapping the methylome EV Epigenomics Cell Cycle 5 (2), 155-158, 2006 | 225* | 2006 |
Limiting the proliferation of polyploid cells NJ Ganem, D Pellman Cell 131 (3), 437-440, 2007 | 214 | 2007 |
Whole-genome doubling confers unique genetic vulnerabilities on tumour cells RJ Quinton, A DiDomizio, MA Vittoria, K Kotýnková, CJ Ticas, S Patel, ... Nature 590 (7846), 492-497, 2021 | 209 | 2021 |
LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control W Gan, X Dai, X Dai, J Xie, S Yin, J Zhu, C Wang, Y Liu, J Guo, M Wang, ... Nature cell biology 22 (2), 246-256, 2020 | 86 | 2020 |
Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors AG Henssen, C Reed, E Jiang, HD Garcia, J von Stebut, IC MacArthur, ... Science translational medicine 9 (414), eaam9078, 2017 | 71 | 2017 |
Nuclear envelope rupture drives genome instability in cancer S Lim, RJ Quinton, NJ Ganem Molecular biology of the cell 27 (21), 3210-3213, 2016 | 62 | 2016 |
Identification of the kinase STK25 as an upstream activator of LATS signaling S Lim, N Hermance, T Mudianto, HM Mustaly, IPM Mauricio, MA Vittoria, ... Nature Communications 10 (1), 1547, 2019 | 54 | 2019 |
Genomic instability: Crossing pathways at the origin of structural and numerical chromosome changes A Russo, F Pacchierotti, D Cimini, NJ Ganem, A Genescà, AT Natarajan, ... Environmental and molecular mutagenesis 56 (7), 563-580, 2015 | 40 | 2015 |
Emi1 maintains genomic integrity during zebrafish embryogenesis and cooperates with p53 in tumor suppression J Rhodes, A Amsterdam, T Sanda, LA Moreau, K McKenna, S Heinrichs, ... Molecular and cellular biology 29 (21), 5911-5922, 2009 | 38 | 2009 |
The interplay between centrosomes and the Hippo tumor suppressor pathway AF Bolgioni, NJ Ganem Chromosome Research 24, 93-104, 2016 | 26 | 2016 |