| Reprogramming human T cell function and specificity with non-viral genome targeting TL Roth, C Puig-Saus, R Yu, E Shifrut, J Carnevale, PJ Li, J Hiatt, J Saco, ... Nature 559 (7714), 405-409, 2018 | 863 | 2018 |
| Generation of knock-in primary human T cells using Cas9 ribonucleoproteins K Schumann, S Lin, E Boyer, DR Simeonov, M Subramaniam, RE Gate, ... Proceedings of the National Academy of Sciences 112 (33), 10437-10442, 2015 | 843 | 2015 |
| CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells LJ Rupp, K Schumann, KT Roybal, RE Gate, CJ Ye, WA Lim, A Marson Scientific reports 7 (1), 1-10, 2017 | 764 | 2017 |
| Immobilized chemokine fields and soluble chemokine gradients cooperatively shape migration patterns of dendritic cells K Schumann, T Lämmermann, M Bruckner, DF Legler, J Polleux, JP Spatz, ... Immunity 32 (5), 703-713, 2010 | 395 | 2010 |
| A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors RJ Park, T Wang, D Koundakjian, JF Hultquist, P Lamothe-Molina, ... Nature genetics 49 (2), 193-203, 2017 | 380 | 2017 |
| Adaptive force transmission in amoeboid cell migration J Renkawitz, K Schumann, M Weber, T Lämmermann, H Pflicke, M Piel, ... Nature cell biology 11 (12), 1438-1443, 2009 | 342 | 2009 |
| Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis ND Mathewson, O Ashenberg, I Tirosh, S Gritsch, EM Perez, S Marx, ... Cell 184 (5), 1281-1298. e26, 2021 | 314 | 2021 |
| Discovery of stimulation-responsive immune enhancers with CRISPR activation DR Simeonov, BG Gowen, M Boontanrart, TL Roth, JD Gagnon, ... Nature 549 (7670), 111-115, 2017 | 306 | 2017 |
| A Cas9 ribonucleoprotein platform for functional genetic studies of HIV-host interactions in primary human T cells JF Hultquist, K Schumann, JM Woo, L Manganaro, MJ McGregor, ... Cell reports 17 (5), 1438-1452, 2016 | 211 | 2016 |
| Orthotopic replacement of T-cell receptor α-and β-chains with preservation of near-physiological T-cell function K Schober, TR Müller, F Gökmen, S Grassmann, M Effenberger, ... Nature biomedical engineering 3 (12), 974-984, 2019 | 179 | 2019 |
| Lymph node T cell homeostasis relies on steady state homing of dendritic cells M Wendland, S Willenzon, J Kocks, AC Davalos-Misslitz, ... Immunity 35 (6), 945-957, 2011 | 137 | 2011 |
| CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions JF Hultquist, J Hiatt, K Schumann, MJ McGregor, TL Roth, P Haas, ... Nature protocols 14 (1), 1-27, 2019 | 122 | 2019 |
| Functional CRISPR dissection of gene networks controlling human regulatory T cell identity K Schumann, SS Raju, M Lauber, S Kolb, E Shifrut, JT Cortez, N Skartsis, ... Nature immunology 21 (11), 1456-1466, 2020 | 80 | 2020 |
| In vivo analysis of uropod function during physiological T cell trafficking SF Soriano, M Hons, K Schumann, V Kumar, TJ Dennier, R Lyck, M Sixt, ... The Journal of Immunology 187 (5), 2356-2364, 2011 | 79 | 2011 |
| Regulatory T cells use arginase 2 to enhance their metabolic fitness in tissues MM Lowe, I Boothby, S Clancy, RS Ahn, W Liao, DN Nguyen, ... JCI insight 4 (24), e129756, 2019 | 78 | 2019 |
| Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy TR Müller, S Jarosch, M Hammel, J Leube, S Grassmann, B Bernard, ... Cell Reports Medicine 2 (8), 2021 | 47 | 2021 |
| Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8+ T cells F Winkler, AV Hipp, C Ramirez, B Martin, M Villa, E Neuwirt, O Gorka, ... Gut 72 (10), 1971-1984, 2023 | 12 | 2023 |
| FoxP3 expression by retinal pigment epithelial cells: transcription factor with potential relevance for the pathology of age-related macular degeneration AS Alfaar, L Stürzbecher, M Diedrichs-Möhring, M Lam, C Roubeix, ... Journal of Neuroinflammation 19 (1), 260, 2022 | 12 | 2022 |
| CRISPR/Cas-based human T cell engineering: basic research and clinical application BE Bernard, E Landmann, LT Jeker, K Schumann Immunology Letters 245, 18-28, 2022 | 10 | 2022 |
| Human interleukin-12α and EBI3 are cytokines with anti-inflammatory functions K Hildenbrand, S Bohnacker, PR Menon, A Kerle, UF Prodjinotho, ... Science advances 9 (43), eadg6874, 2023 | 7 | 2023 |
Alexander MarsonDirector of Gladstone-UCSF Institute of Genomic Immunology, Professor, Department of MedicineVerifierad e-postadress på ucsf.edu
