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Yupeng Li
Yupeng Li
School of Pharmacy, The University of Texas at El Paso
Verifierad e-postadress på utep.edu
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Carcinogenic components of tobacco and tobacco smoke: A 2022 update
Y Li, SS Hecht
Food and Chemical Toxicology 165, 113179, 2022
1662022
Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region–abelson (Bcr-Abl) kinase and overcomes …
X Ren, X Pan, Z Zhang, D Wang, X Lu, Y Li, D Wen, H Long, J Luo, ...
Journal of medicinal chemistry 56 (3), 879-894, 2013
1592013
Nanoparticle‐conjugate TLR7/8 agonist localized immunotherapy provokes safe antitumoral responses
L Nuhn, S De Koker, S Van Lint, Z Zhong, JP Catani, F Combes, ...
Advanced Materials 30 (45), 1803397, 2018
1492018
Metabolic Activation and DNA Interactions of Carcinogenic N-Nitrosamines to Which Humans Are Commonly Exposed
Y Li, SS Hecht
International journal of molecular sciences 23 (9), 4559, 2022
1222022
Coumarin–benzimidazole hybrids: A review of developments in medicinal chemistry
CG Arya, R Gondru, Y Li, J Banothu
European journal of medicinal chemistry 227, 113921, 2022
902022
Small Molecule Discoidin Domain Receptor Kinase Inhibitors and Potential Medical Applications: Miniperspective
Y Li, X Lu, X Ren, K Ding
Journal of medicinal chemistry 58 (8), 3287-3301, 2015
762015
Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist
L Nuhn, L Van Hoecke, K Deswarte, B Schepens, Y Li, BN Lambrecht, ...
Biomaterials 178, 643-651, 2018
642018
Discovery of the first-in-class agonist-based SOS1 PROTACs effective in human cancer cells harboring various KRAS mutations
C Zhou, Z Fan, Z Zhou, Y Li, R Cui, C Liu, G Zhou, X Diao, H Jiang, ...
Journal of medicinal chemistry 65 (5), 3923-3942, 2022
582022
Lymph-node-targeted immune activation by engineered block copolymer amphiphiles–TLR7/8 agonist conjugates
S Van Herck, K Deswarte, L Nuhn, Z Zhong, JP Portela Catani, Y Li, ...
Journal of the American Chemical Society 140 (43), 14300-14307, 2018
582018
Design, synthesis, and biological evaluation of 3-(1 H-1, 2, 3-triazol-1-yl) benzamide derivatives as potent pan Bcr-Abl inhibitors including the threonine315→ isoleucine315 …
Y Li, M Shen, Z Zhang, J Luo, X Pan, X Lu, H Long, D Wen, F Zhang, ...
Journal of medicinal chemistry 55 (22), 10033-10046, 2012
462012
Metabolism and DNA Adduct Formation of Tobacco-Specific N-Nitrosamines
Y Li, SS Hecht
International journal of molecular sciences 23 (9), 5109, 2022
422022
Hyaluronic acid conjugates of TLR7/8 agonists for targeted delivery to secondary lymphoid tissue
E Yoo, ACD Salyer, MJH Brush, Y Li, KL Trautman, NM Shukla, ...
Bioconjugate chemistry 29 (8), 2741-2754, 2018
332018
Design, synthesis, and biological evaluation of novel EGFR PROTACs targeting Del19/T790M/C797S mutation
H Zhang, R Xie, H Ai-Furas, Y Li, Q Wu, J Li, F Xu, T Xu
ACS Medicinal Chemistry Letters 13 (2), 278-283, 2022
312022
Discovery of a potent, cooperative, and selective SOS1 PROTAC ZZ151 with in vivo antitumor efficacy in KRAS-mutant cancers
Z Zhou, G Zhou, C Zhou, Z Fan, R Cui, Y Li, R Li, Y Gu, H Li, Z Ge, X Cai, ...
Journal of medicinal chemistry 66 (6), 4197-4214, 2023
232023
Resolution and quantitation of mercapturic acids derived from crotonaldehyde, methacrolein, and methyl vinyl ketone in the urine of smokers and nonsmokers
M Chen, SG Carmella, Y Li, Y Zhao, SS Hecht
Chemical research in toxicology 33 (2), 669-677, 2020
192020
Design and Optimization of 3′-(Imidazo[1,2-a]pyrazin-3-yl)-[1,1′-biphenyl]-3-carboxamides as Selective DDR1 Inhibitors
C Mo, Z Zhang, Y Li, M Huang, J Zou, J Luo, ZC Tu, Y Xu, X Ren, K Ding, ...
ACS Medicinal Chemistry Letters 11 (3), 379-384, 2020
172020
Ionizable drug delivery systems for efficient and selective gene therapy
YQ Zhang, RR Guo, YH Chen, TC Li, WZ Du, RW Xiang, JB Guan, YP Li, ...
Military Medical Research 10 (1), 1-29, 2023
152023
Mass Spectrometric Quantitation of Pyridyloxobutyl DNA Phosphate Adducts in Rats Chronically Treated with N′-Nitrosonornicotine
Y Li, B Ma, Q Cao, S Balbo, L Zhao, P Upadhyaya, SS Hecht
Chemical research in toxicology 32 (4), 773-783, 2019
142019
Identification of an N′-Nitrosonornicotine-Specific Deoxyadenosine Adduct in Rat Liver and Lung DNA
Y Li, SS Hecht
Chemical research in toxicology 34 (4), 992-1003, 2021
132021
Design, Synthesis, and Bioevaluation of Pyrido[2,3-d]pyrimidin-7-ones as Potent SOS1 Inhibitors
M Liu, G Zhou, W Su, Y Gu, M Gao, K Wang, R Huo, Y Li, Z Zhou, K Chen, ...
ACS Medicinal Chemistry Letters 14 (2), 183-190, 2023
122023
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