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Anastasia Khvorova
Anastasia Khvorova
UMASS Medical School
Verifierad e-postadress på umassmed.edu
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Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the …
C Théry, KW Witwer, E Aikawa, MJ Alcaraz, JD Anderson, ...
Journal of extracellular vesicles 7 (1), 1535750, 2018
96792018
Functional siRNAs and miRNAs exhibit strand bias
A Khvorova, A Reynolds, SD Jayasena
Cell 115 (2), 209-216, 2003
40422003
Rational siRNA design for RNA interference
A Reynolds, D Leake, Q Boese, S Scaringe, WS Marshall, A Khvorova
Nature biotechnology 22 (3), 326-330, 2004
30132004
3′ UTR seed matches, but not overall identity, are associated with RNAi off-targets
A Birmingham, EM Anderson, A Reynolds, D Ilsley-Tyree, D Leake, ...
Nature methods 3 (3), 199-204, 2006
12302006
The chemical evolution of oligonucleotide therapies of clinical utility
A Khvorova, JK Watts
Nature biotechnology 35 (3), 238-248, 2017
11522017
Position-specific chemical modification of siRNAs reduces “off-target” transcript silencing
AL Jackson, J Burchard, D Leake, A Reynolds, J Schelter, J Guo, ...
Rna 12 (7), 1197-1205, 2006
10912006
Functional and hyperfunctional siRNA
A Khvorova, A Reynolds, D Leake, W Marshall, S Scaringe
US Patent 8,090,542, 2012
10042012
Identification of the gene for vitamin K epoxide reductase
T Li, CY Chang, DY Jin, PJ Lin, A Khvorova, DW Stafford
Nature 427 (6974), 541-544, 2004
9382004
High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources
RA Haraszti, MC Didiot, E Sapp, J Leszyk, SA Shaffer, HE Rockwell, ...
Journal of extracellular vesicles 5 (1), 32570, 2016
7012016
Off-target effects by siRNA can induce toxic phenotype
Y Fedorov, EM Anderson, A Birmingham, A Reynolds, J Karpilow, ...
Rna 12 (7), 1188-1196, 2006
6912006
Methods and compositions for selecting siRNA of improved functionality
A Khvorova, A Reynolds, D Leake, W Marshall, S Read, S Scaringe
US Patent App. 10/940,892, 2005
5672005
Analysis of Clathrin-Mediated Endocytosis of Epidermal Growth Factor Receptor by RNA Interference*[Boxs]
F Huang, A Khvorova, W Marshall, A Sorkin
Journal of Biological Chemistry 279 (16), 16657-16661, 2004
5602004
Sequence elements outside the hammerhead ribozyme catalytic core enable intracellular activity
A Khvorova, A Lescoute, E Westhof, SD Jayasena
Nature Structural & Molecular Biology 10 (9), 708-712, 2003
5472003
Functional and hyperfunctional siRNA
A Khvorova, A Reynolds, D Leake, W Marshall, S Scaringe, S Read
US Patent 7,691,997, 2010
5302010
Identification of genes that regulate epithelial cell migration using an siRNA screening approach
KJ Simpson, LM Selfors, J Bui, A Reynolds, D Leake, A Khvorova, ...
Nature cell biology 10 (9), 1027-1038, 2008
5022008
Exosome-mediated delivery of hydrophobically modified siRNA for huntingtin mRNA silencing
MC Didiot, LM Hall, AH Coles, RA Haraszti, BMDC Godinho, K Chase, ...
Molecular Therapy 24 (10), 1836-1847, 2016
4992016
RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells
JA Wilson, S Jayasena, A Khvorova, S Sabatinos, IG Rodrigue-Gervais, ...
Proceedings of the National Academy of Sciences 100 (5), 2783-2788, 2003
4532003
Induction of the interferon response by siRNA is cell type–and duplex length–dependent
A Reynolds, EM Anderson, A Vermeulen, Y Fedorov, K Robinson, ...
Rna 12 (6), 988-993, 2006
4522006
Exosomes produced from 3D cultures of MSCs by tangential flow filtration show higher yield and improved activity
RA Haraszti, R Miller, M Stoppato, YY Sere, A Coles, MC Didiot, ...
Molecular Therapy 26 (12), 2838-2847, 2018
4372018
A USP28–53BP1–p53–p21 signaling axis arrests growth after centrosome loss or prolonged mitosis
BG Lambrus, V Daggubati, Y Uetake, PM Scott, KM Clutario, G Sluder, ...
Journal of Cell Biology 214 (2), 143-153, 2016
417*2016
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Artiklar 1–20