| Dynamic reorganization of chromatin accessibility signatures during dedifferentiation of secretory precursors into Lgr5+ intestinal stem cells U Jadhav, M Saxena, NK O’Neill, A Saadatpour, GC Yuan, Z Herbert, ... Cell Stem Cell 21 (1), 65-77. e5, 2017 | 272 | 2017 |
| Acquired Tissue-Specific Promoter Bivalency Is a Basis for PRC2 Necessity in Adult Cells U Jadhav, K Nalapareddy, M Saxena, NK O’Neill, L Pinello, GC Yuan, ... Cell 165 (6), 1389-1400, 2016 | 146 | 2016 |
| SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling KR Holloway, TN Calhoun, M Saxena, CF Metoyer, EF Kandler, ... Proceedings of the National Academy of Sciences 107 (20), 9216-9221, 2010 | 130 | 2010 |
| Single-Cell Transcript Profiles Reveal Multilineage Priming in Early Progenitors Derived from Lgr5+ Intestinal Stem Cells TH Kim, A Saadatpour, G Guo, M Saxena, A Cavazza, N Desai, U Jadhav, ... Cell reports 16 (8), 2053-2060, 2016 | 109 | 2016 |
| SIRT1 positively regulates breast cancer associated human aromatase (CYP19A1) expression KR Holloway, A Barbieri, S Malyarchuk, M Saxena, A Nedeljkovic-Kurepa, ... Molecular endocrinology 27 (3), 480-490, 2013 | 82 | 2013 |
| The lineage-specific transcription factor CDX2 navigates dynamic chromatin to control distinct stages of intestine development N Kumar, YH Tsai, L Chen, A Zhou, KK Banerjee, M Saxena, S Huang, ... Development 146 (5), dev172189, 2019 | 81 | 2019 |
| The Arf-like GTPase Arl8b is essential for three-dimensional invasive growth of prostate cancer in vitro and xenograft formation and growth in vivo SS Dykes, AL Gray, DT Coleman, M Saxena, CA Stephens, JL Carroll, ... Oncotarget 7 (21), 31037, 2016 | 64 | 2016 |
| Effect of tamoxifen treatment on global and insulin-like growth factor 2-H19 locus-specific DNA methylation in rat spermatozoa and its association with embryo loss S Pathak, N Kedia-Mokashi, M Saxena, R D'Souza, A Maitra, P Parte, ... Fertility and sterility 91 (5), 2253-2263, 2009 | 64 | 2009 |
| Frizzled 7 expression is positively regulated by SIRT1 and β-catenin in breast cancer cells GE Simmons Jr, S Pandey, A Nedeljkovic-Kurepa, M Saxena, A Wang, ... PloS one 9 (6), e98861, 2014 | 58 | 2014 |
| The sirtuins promote Dishevelled-1 scaffolding of TIAM1, Rac activation and cell migration M Saxena, SS Dykes, S Malyarchuk, AE Wang, JA Cardelli, K Pruitt Oncogene 34 (2), 188-198, 2015 | 57 | 2015 |
| Transcription factor-dependent ‘anti-repressive’mammalian enhancers exclude H3K27me3 from extended genomic domains M Saxena, AK San Roman, NK O'Neill, R Sulahian, U Jadhav, ... Genes & Development 31, 2391-2404, 2017 | 43 | 2017 |
| Krüppel-like factor 5 regulates stemness, lineage specification, and regeneration of intestinal epithelial stem cells CK Kim, M Saxena, K Maharjan, JJ Song, KR Shroyer, AB Bialkowska, ... Cellular and molecular gastroenterology and hepatology 9 (4), 587-609, 2020 | 37 | 2020 |
| Enhancer, transcriptional, and cell fate plasticity precedes intestinal determination during endoderm development KK Banerjee, M Saxena, N Kumar, L Chen, A Cavazza, NH Toke, ... Genes & development 32 (21-22), 1430-1442, 2018 | 36 | 2018 |
| Disrupted imprinting status at the H19 differentially methylated region is associated with the resorbed embryo phenotype in rats S Pathak, M Saxena, R D'Souza, NH Balasinor Reproduction, Fertility and Development 22 (6), 939-948, 2010 | 29 | 2010 |
| Transcription factor-mediated intestinal metaplasia and the role of a shadow enhancer H Singh, D Seruggia, S Madha, M Saxena, AK Nagaraja, Z Wu, J Zhou, ... Genes & Development 36 (1-2), 38-52, 2022 | 18 | 2022 |
| Epigenetic Signatures and Plasticity of Intestinal and Other Stem Cells M Saxena, RA Shivdasani Annual Reviews of Physiology 83, 2021 | 11 | 2021 |
| Chromosomal aberration in the post-implantation embryos sired by tamoxifen treated male rats N Kedia-Mokashi, AEL Makawy, M Saxena, NH Balasinor Mutation Research/Genetic Toxicology and Environmental Mutagenesis 703 (2 …, 2010 | 10 | 2010 |
| Cochlear organoids reveal transcriptional programs of postnatal hair cell differentiation from supporting cells G Kalra, D Lenz, D Abdul-Aziz, C Hanna, M Basu, BR Herb, C Colantuoni, ... Cell Reports 42 (11), 2023 | 8 | 2023 |
| A Phase 1, randomized, double-blind, placebo-controlled, single-and multiple-dose escalation study to evaluate the safety and pharmacokinetics/pharmacodynamics of PF-06835375 … S Cohen, JS Beebe, V Chindalore, S Guan, M Hassan-Zahraee, ... Arthritis Research & Therapy 26 (1), 1-18, 2024 | 1 | 2024 |
| The anti-interferon-beta neutralizing antibody PF-06823859 significantly improves molecular and histological profiles in the skin of patients with dermatomyositis in a 12-week … K Page, X Li, R Aggarwal, C Banfield, D Fiorentino, K Hammerman, W He, ... 32nd EADV Congress 2023, Berlin, Germany, 2023 | | 2023 |
