HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia J Kim, I Tchernyshyov, GL Semenza, CV Dang Cell metabolism 3 (3), 177-185, 2006 | 4418 | 2006 |
c-Myc-regulated microRNAs modulate E2F1 expression KA O'Donnell, EA Wentzel, KI Zeller, CV Dang, JT Mendell nature 435 (7043), 839-843, 2005 | 3855 | 2005 |
MYC on the path to cancer CV Dang Cell 149 (1), 22-35, 2012 | 3697 | 2012 |
Otto Warburg's contributions to current concepts of cancer metabolism WH Koppenol, PL Bounds, CV Dang Nature Reviews Cancer 11 (5), 325-337, 2011 | 3613 | 2011 |
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism P Gao, I Tchernyshyov, TC Chang, YS Lee, K Kita, T Ochi, KI Zeller, ... Nature 458 (7239), 762-765, 2009 | 2418 | 2009 |
c-Myc target genes involved in cell growth, apoptosis, and metabolism CV Dang Molecular and cellular biology 19 (1), 1-11, 1999 | 2200 | 1999 |
From Krebs to clinic: glutamine metabolism to cancer therapy BJ Altman, ZE Stine, CV Dang Nature Reviews Cancer 16 (10), 619-634, 2016 | 2191 | 2016 |
Control of TH17/Treg balance by hypoxia-inducible factor 1 EV Dang, J Barbi, HY Yang, D Jinasena, H Yu, Y Zheng, Z Bordman, J Fu, ... Cell 146 (5), 772-784, 2011 | 1739 | 2011 |
Widespread microRNA repression by Myc contributes to tumorigenesis TC Chang, D Yu, YS Lee, EA Wentzel, DE Arking, KM West, CV Dang, ... Nature genetics 40 (1), 43-50, 2008 | 1717 | 2008 |
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression A Le, CR Cooper, AM Gouw, R Dinavahi, A Maitra, LM Deck, RE Royer, ... Proceedings of the National Academy of Sciences 107 (5), 2037-2042, 2010 | 1596 | 2010 |
Cancer's molecular sweet tooth and the Warburg effect J Kim, CV Dang Cancer research 66 (18), 8927-8930, 2006 | 1566 | 2006 |
The c-Myc target gene network CV Dang, KA O’Donnell, KI Zeller, T Nguyen, RC Osthus, F Li Seminars in cancer biology 16 (4), 253-264, 2006 | 1490 | 2006 |
HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells R Fukuda, H Zhang, J Kim, L Shimoda, CV Dang, GL Semenza Cell 129 (1), 111-122, 2007 | 1488 | 2007 |
Oncogenic alterations of metabolism CV Dang, GL Semenza Trends in biochemical sciences 24 (2), 68-72, 1999 | 1466 | 1999 |
c-Myc transactivation of LDH-A: Implications for tumor metabolism and growth H Shim, C Dolde, BC Lewis, CS Wu, G Dang, RA Jungmann, ... Proceedings of the national academy of sciences 94 (13), 6658-6663, 1997 | 1396 | 1997 |
Development of human protein reference database as an initial platform for approaching systems biology in humans S Peri, JD Navarro, R Amanchy, TZ Kristiansen, CK Jonnalagadda, ... Genome research 13 (10), 2363-2371, 2003 | 1350 | 2003 |
MYC, metabolism, and cancer ZE Stine, ZE Walton, BJ Altman, AL Hsieh, CV Dang Cancer discovery 5 (10), 1024-1039, 2015 | 1246 | 2015 |
Links between metabolism and cancer CV Dang Genes & development 26 (9), 877-890, 2012 | 1233 | 2012 |
Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells A Le, AN Lane, M Hamaker, S Bose, A Gouw, J Barbi, T Tsukamoto, ... Cell metabolism 15 (1), 110-121, 2012 | 1225 | 2012 |
MYC-induced cancer cell energy metabolism and therapeutic opportunities CV Dang, A Le, P Gao Clinical cancer research 15 (21), 6479-6483, 2009 | 1072 | 2009 |