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A Jeremy Willsey
A Jeremy Willsey
Associate Director of Data Science, Calico Life Sciences
Verifierad e-postadress på calicolabs.com - Startsida
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Synaptic, transcriptional and chromatin genes disrupted in autism
S De Rubeis, X He, AP Goldberg, CS Poultney, K Samocha, ...
Nature 515 (7526), 209-215, 2014
29752014
The contribution of de novo coding mutations to autism spectrum disorder
I Iossifov, BJ O’roak, SJ Sanders, M Ronemus, N Krumm, D Levy, ...
Nature 515 (7526), 216-221, 2014
27642014
De novo mutations revealed by whole-exome sequencing are strongly associated with autism
SJ Sanders, MT Murtha, AR Gupta, JD Murdoch, MJ Raubeson, ...
Nature 485 (7397), 237-241, 2012
24392012
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
B Devlin, JR Kelsoe, P Sklar, MJ Daly, MC O'Donovan, N Craddock, ...
Nature genetics 45 (9), 984-994, 2013
24322013
Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism
FK Satterstrom, JA Kosmicki, J Wang, MS Breen, S De Rubeis, JY An, ...
Cell 180 (3), 568-584. e23, 2020
20322020
Insights into autism spectrum disorder genomic architecture and biology from 71 risk loci
SJ Sanders, X He, AJ Willsey, AG Ercan-Sencicek, KE Samocha, ...
Neuron 87 (6), 1215-1233, 2015
15762015
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders
PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ...
Cell 179 (7), 1469-1482. e11, 2019
11892019
Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder
MJ Gandal, P Zhang, E Hadjimichael, RL Walker, C Chen, S Liu, H Won, ...
Science 362 (6420), eaat8127, 2018
11582018
Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism
AJ Willsey, SJ Sanders, M Li, S Dong, AT Tebbenkamp, RA Muhle, ...
Cell 155 (5), 997-1007, 2013
10152013
Comprehensive functional genomic resource and integrative model for the human brain
D Wang, S Liu, J Warrell, H Won, X Shi, FCP Navarro, D Clarke, M Gu, ...
Science 362 (6420), eaat8464, 2018
9312018
Integrative functional genomic analysis of human brain development and neuropsychiatric risks
M Li, G Santpere, Y Imamura Kawasawa, OV Evgrafov, FO Gulden, ...
Science 362 (6420), eaat7615, 2018
7252018
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways
B Devlin, JR Kelsoe, P Sklar, MJ Daly, MC O'Donovan, N Craddock, ...
Nature neuroscience 18 (2), 199-209, 2015
5482015
Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders
DJ Weiner, EM Wigdor, S Ripke, RK Walters, JA Kosmicki, J Grove, ...
Nature genetics 49 (7), 978-985, 2017
5062017
Common genetic variants, acting additively, are a major source of risk for autism
L Klei, SJ Sanders, MT Murtha, V Hus, JK Lowe, AJ Willsey, ...
Molecular autism 3, 1-13, 2012
4812012
The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment
J Cotney, RA Muhle, SJ Sanders, L Liu, AJ Willsey, W Niu, W Liu, L Klei, ...
Nature communications 6 (1), 6404, 2015
3722015
The psychencode project
S Akbarian, C Liu, JA Knowles, FM Vaccarino, PJ Farnham, GE Crawford, ...
Nature neuroscience 18 (12), 1707-1712, 2015
3682015
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24. 32 and a significant overlap with schizophrenia
Molecular autism 8, 1-17, 2017
3612017
Interrogating the genetic determinants of Tourette’s syndrome and other tic disorders through genome-wide association studies
D Yu, JH Sul, F Tsetsos, MS Nawaz, AY Huang, I Zelaya, C Illmann, ...
American Journal of Psychiatry 176 (3), 217-227, 2019
3372019
Genome-wide de novo risk score implicates promoter variation in autism spectrum disorder
JY An, K Lin, L Zhu, DM Werling, S Dong, H Brand, HZ Wang, X Zhao, ...
Science 362 (6420), eaat6576, 2018
3102018
Comparative flavivirus-host protein interaction mapping reveals mechanisms of dengue and Zika virus pathogenesis
PS Shah, N Link, GM Jang, PP Sharp, T Zhu, DL Swaney, JR Johnson, ...
Cell 175 (7), 1931-1945. e18, 2018
3102018
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