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Rajagopal Murugan
Rajagopal Murugan
Assistant Professor, Leiden University Center for Infectious Diseases, LUMC, Leiden, The Netherlands
Verifierad e-postadress på lumc.nl
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Human cerebrospinal fluid monoclonal N -methyl-D-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis
J Kreye, NK Wenke, M Chayka, J Leubner, R Murugan, N Maier, B Jurek, ...
Brain 139 (10), 2641-2652, 2016
2872016
Natural parasite exposure induces protective human anti-malarial antibodies
G Triller, SW Scally, G Costa, M Pissarev, C Kreschel, A Bosch, E Marois, ...
Immunity 47 (6), 1197-1209. e10, 2017
1522017
Clonal selection drives protective memory B cell responses in controlled human malaria infection
R Murugan, L Buchauer, G Triller, C Kreschel, G Costa, ...
Science immunology 3 (20), eaap8029, 2018
1512018
Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope
K Imkeller, SW Scally, A Bosch, GP Martí, G Costa, G Triller, R Murugan, ...
Science 360 (6395), 1358-1362, 2018
1032018
Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection
SW Scally, R Murugan, A Bosch, G Triller, G Costa, B Mordmüller, ...
Journal of Experimental Medicine 215 (1), 63-75, 2018
882018
Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs
R Murugan, SW Scally, G Costa, G Mustafa, E Thai, T Decker, A Bosch, ...
Nature medicine 26 (7), 1135-1145, 2020
862020
Direct high‐throughput amplification and sequencing of immunoglobulin genes from single human B cells
R Murugan, K Imkeller, CE Busse, H Wardemann
European journal of immunology 45 (9), 2698, 2015
502015
A putative low-molecular-mass penicillin-binding protein (PBP) of Mycobacterium smegmatis exhibits prominent physiological characteristics of DD-carboxypeptidase and beta-lactamase
A Bansal, D Kar, RA Murugan, S Mallick, M Dutta, SD Pandey, ...
Microbiology 161 (5), 1081-1091, 2015
432015
A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity
E Thai, G Costa, A Weyrich, R Murugan, D Oyen, Y Flores-Garcia, K Prieto, ...
Journal of Experimental Medicine 217 (11), e20200061, 2020
252020
From multiplex serology to serolomics—A novel approach to the antibody response against the SARS-CoV-2 proteome
J Butt, R Murugan, T Hippchen, S Olberg, M van Straaten, H Wardemann, ...
Viruses 13 (5), 749, 2021
152021
From human antibody structure and function towards the design of a novel Plasmodium falciparum circumsporozoite protein malaria vaccine
H Wardemann, R Murugan
Current opinion in immunology 53, 119-123, 2018
152018
Molecular and functional properties of human Plasmodium falciparum CSP C‐terminus antibodies
OE Oludada, G Costa, C Burn Aschner, AS Obraztsova, K Prieto, ...
EMBO Molecular Medicine 15 (6), e17454, 2023
102023
Glycosylated nanoparticle-based PfCSP vaccine confers long-lasting antibody responses and sterile protection in mouse malaria model
J Ludwig, SW Scally, G Costa, S Hoffmann, R Murugan, J Lossin, K Prieto, ...
npj Vaccines 8 (1), 52, 2023
102023
Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein
E Thai, R Murugan, Š Binter, CB Aschner, K Prieto, A Kassardjian, ...
Cell Reports 42 (11), 2023
82023
High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire
I Kucharska, Š Binter, R Murugan, SW Scally, J Ludwig, K Prieto, E Thai, ...
Plos Pathogens 18 (11), e1010999, 2022
82022
Safety and Efficacy of Immunization with a Late-Liver-Stage Attenuated Malaria Parasite
OAC Lamers, BMD Franke-Fayard, JPR Koopman, GVT Roozen, ...
New England Journal of Medicine 391 (20), 1913-1923, 2024
62024
Single immunization with genetically attenuated Pf∆mei2 (GA2) parasites by mosquito bite in controlled human malaria infection: a placebo-controlled randomized …
GVT Roozen, R van Schuijlenburg, ADO Hensen, JPR Koopman, ...
Nature Medicine, 1-5, 2025
12025
Affinity-independent memory B cell origin of the early antibody-secreting cell response in naive individuals upon SARS-CoV-2 vaccination
Z Li, A Obraztsova, F Shang, OE Oludada, J Malapit, K Busch, ...
Immunity 57 (9), 2191-2201. e5, 2024
12024
Safety, Tolerability, and Immunogenicity of the InvaplexAR-Detox Shigella Vaccine Co-Administered with the dmLT Adjuvant in Dutch and Zambian Adults: Study …
GVT Roozen, N Sukwa, M Chirwa, JA White, M Estrada, N Maier, ...
Vaccines 13 (1), 48, 2025
2025
Expression Cloning of Antibodies from Single Human B Cells
T Rollenske, R Murugan, H Wardemann, CE Busse
Lymphoma: Methods and Protocols, 103-124, 2024
2024
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Artiklar 1–20