mTORC1 and mTORC2 in cancer and the tumor microenvironment LC Kim, RS Cook, J Chen Oncogene 36 (16), 2191-2201, 2017 | 452 | 2017 |
Selective glutamine metabolism inhibition in tumor cells improves antitumor T lymphocyte activity in triple-negative breast cancer DN Edwards, VM Ngwa, AL Raybuck, S Wang, Y Hwang, LC Kim, SH Cho, ... The Journal of clinical investigation 131 (4), 2021 | 250 | 2021 |
Divergent lncRNA GATA3-AS1 Regulates GATA3 Transcription in T-Helper 2 Cells HR Gibbons, G Shaginurova, LC Kim, N Chapman, CF Spurlock III, ... Frontiers in immunology 9, 2512, 2018 | 120 | 2018 |
The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ DN Edwards, VM Ngwa, S Wang, E Shiuan, DM Brantley-Sieders, LC Kim, ... Science signaling 10 (508), 2017 | 109 | 2017 |
GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment R Missiaen, NM Anderson, LC Kim, B Nance, M Burrows, N Skuli, ... Cell metabolism 34 (8), 1151-1167. e7, 2022 | 95 | 2022 |
The ephrin-A1/EPHA2 signaling axis regulates glutamine metabolism in HER2-positive breast cancer VM Youngblood, LC Kim, DN Edwards, Y Hwang, PR Santapuram, ... Cancer research 76 (7), 1825-1836, 2016 | 81 | 2016 |
Disruption of the Scaffolding Function of mLST8 Selectively Inhibits mTORC2 Assembly and Function and Suppresses mTORC2-Dependent Tumor Growth In Vivo Y Hwang, LC Kim, W Song, DN Edwards, RS Cook, J Chen Cancer research 79 (13), 3178-3184, 2019 | 60 | 2019 |
Disrupting cellular memory to overcome drug resistance G Harmange, RAR Hueros, DL Schaff, B Emert, M Saint-Antoine, LC Kim, ... Nature communications 14 (1), 7130, 2023 | 40 | 2023 |
Hypoxia-inducible factors in cancer LC Kim, MC Simon Cancer research 82 (2), 195-196, 2022 | 31 | 2022 |
Medullary norepinephrine neurons modulate local oxygen concentrations in the bed nucleus of the stria terminalis ES Bucher, ME Fox, L Kim, DC Kirkpatrick, NT Rodeberg, AM Belle, ... Journal of Cerebral Blood Flow & Metabolism 34 (7), 1128-1137, 2014 | 24 | 2014 |
ASS1 and ASL suppress growth in clear cell renal cell carcinoma via altered nitrogen metabolism S Khare, LC Kim, G Lobel, PT Doulias, H Ischiropoulos, I Nissim, B Keith, ... Cancer & Metabolism 9, 1-16, 2021 | 22 | 2021 |
Fructose-1, 6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness L Gu, Y Zhu, K Watari, M Lee, J Liu, S Perez, M Thai, JE Mayfield, ... Cell metabolism 35 (6), 1009-1021. e9, 2023 | 13 | 2023 |
Phosphorylation of PLCγ1 by EphA2 receptor tyrosine kinase promotes tumor growth in lung cancer W Song, LC Kim, W Han, Y Hou, DN Edwards, S Wang, TS Blackwell, ... Molecular Cancer Research 18 (11), 1735-1743, 2020 | 13 | 2020 |
RICTOR Amplification Promotes NSCLC Cell Proliferation through Formation and Activation of mTORC2 at the Expense of mTORC1 LC Kim, CH Rhee, J Chen Molecular Cancer Research 18 (11), 1675-1684, 2020 | 7 | 2020 |
Cancer metabolism under limiting oxygen conditions LC Kim, NP Lesner, MC Simon Cold Spring Harbor Perspectives in Medicine 14 (2), a041542, 2024 | 4 | 2024 |
Divergent lncRNA GATA3-AS1 Regulates GATA3 Transcription in T-Helper 2 Cells. Front Immunol. 2018; 9: 2512 HR Gibbons, G Shaginurova, LC Kim, N Chapman, CF Spurlock 3rd, ... PUBMED, 2018 | 4 | 2018 |
Regulation of fatty acid delivery to metastases by tumor endothelium DN Edwards, S Wang, W Song, LC Kim, VM Ngwa, Y Hwang, KC Ess, ... bioRxiv, 2024 | 2 | 2024 |
Regulation of cancer glutamine metabolism by EphA2 RTK-dependent activation of transcriptional co-activators YAP and TAZ DN Edwards, VM Ngwa, S Wang, E Shiuan, D Brantley-Sieders, LC Kim, ... Science signaling 10 (508), eaan4667, 2017 | 2 | 2017 |
Selective inhibition of mTORC2 by disruption of mLST8 scaffolding function LC Kim, Y Hwang, W Song, RS Cook, J Chen Cancer Research 79 (13_Supplement), 3434-3434, 2019 | 1 | 2019 |
Cancer-associated fibroblasts maintain critical pancreatic cancer cell lipid homeostasis in the tumor microenvironment X Han, M Burrows, LC Kim, JP Xu, W Vostrejs, TN Van Le, C Poltorack, ... Cell reports 43 (11), 2024 | | 2024 |