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Laura C. Kim
Laura C. Kim
Verifierad e-postadress på pennmedicine.upenn.edu
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mTORC1 and mTORC2 in cancer and the tumor microenvironment
LC Kim, RS Cook, J Chen
Oncogene 36 (16), 2191-2201, 2017
4522017
Selective glutamine metabolism inhibition in tumor cells improves antitumor T lymphocyte activity in triple-negative breast cancer
DN Edwards, VM Ngwa, AL Raybuck, S Wang, Y Hwang, LC Kim, SH Cho, ...
The Journal of clinical investigation 131 (4), 2021
2502021
Divergent lncRNA GATA3-AS1 Regulates GATA3 Transcription in T-Helper 2 Cells
HR Gibbons, G Shaginurova, LC Kim, N Chapman, CF Spurlock III, ...
Frontiers in immunology 9, 2512, 2018
1202018
The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ
DN Edwards, VM Ngwa, S Wang, E Shiuan, DM Brantley-Sieders, LC Kim, ...
Science signaling 10 (508), 2017
1092017
GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment
R Missiaen, NM Anderson, LC Kim, B Nance, M Burrows, N Skuli, ...
Cell metabolism 34 (8), 1151-1167. e7, 2022
952022
The ephrin-A1/EPHA2 signaling axis regulates glutamine metabolism in HER2-positive breast cancer
VM Youngblood, LC Kim, DN Edwards, Y Hwang, PR Santapuram, ...
Cancer research 76 (7), 1825-1836, 2016
812016
Disruption of the Scaffolding Function of mLST8 Selectively Inhibits mTORC2 Assembly and Function and Suppresses mTORC2-Dependent Tumor Growth In Vivo
Y Hwang, LC Kim, W Song, DN Edwards, RS Cook, J Chen
Cancer research 79 (13), 3178-3184, 2019
602019
Disrupting cellular memory to overcome drug resistance
G Harmange, RAR Hueros, DL Schaff, B Emert, M Saint-Antoine, LC Kim, ...
Nature communications 14 (1), 7130, 2023
402023
Hypoxia-inducible factors in cancer
LC Kim, MC Simon
Cancer research 82 (2), 195-196, 2022
312022
Medullary norepinephrine neurons modulate local oxygen concentrations in the bed nucleus of the stria terminalis
ES Bucher, ME Fox, L Kim, DC Kirkpatrick, NT Rodeberg, AM Belle, ...
Journal of Cerebral Blood Flow & Metabolism 34 (7), 1128-1137, 2014
242014
ASS1 and ASL suppress growth in clear cell renal cell carcinoma via altered nitrogen metabolism
S Khare, LC Kim, G Lobel, PT Doulias, H Ischiropoulos, I Nissim, B Keith, ...
Cancer & Metabolism 9, 1-16, 2021
222021
Fructose-1, 6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness
L Gu, Y Zhu, K Watari, M Lee, J Liu, S Perez, M Thai, JE Mayfield, ...
Cell metabolism 35 (6), 1009-1021. e9, 2023
132023
Phosphorylation of PLCγ1 by EphA2 receptor tyrosine kinase promotes tumor growth in lung cancer
W Song, LC Kim, W Han, Y Hou, DN Edwards, S Wang, TS Blackwell, ...
Molecular Cancer Research 18 (11), 1735-1743, 2020
132020
RICTOR Amplification Promotes NSCLC Cell Proliferation through Formation and Activation of mTORC2 at the Expense of mTORC1
LC Kim, CH Rhee, J Chen
Molecular Cancer Research 18 (11), 1675-1684, 2020
72020
Cancer metabolism under limiting oxygen conditions
LC Kim, NP Lesner, MC Simon
Cold Spring Harbor Perspectives in Medicine 14 (2), a041542, 2024
42024
Divergent lncRNA GATA3-AS1 Regulates GATA3 Transcription in T-Helper 2 Cells. Front Immunol. 2018; 9: 2512
HR Gibbons, G Shaginurova, LC Kim, N Chapman, CF Spurlock 3rd, ...
PUBMED, 2018
42018
Regulation of fatty acid delivery to metastases by tumor endothelium
DN Edwards, S Wang, W Song, LC Kim, VM Ngwa, Y Hwang, KC Ess, ...
bioRxiv, 2024
22024
Regulation of cancer glutamine metabolism by EphA2 RTK-dependent activation of transcriptional co-activators YAP and TAZ
DN Edwards, VM Ngwa, S Wang, E Shiuan, D Brantley-Sieders, LC Kim, ...
Science signaling 10 (508), eaan4667, 2017
22017
Selective inhibition of mTORC2 by disruption of mLST8 scaffolding function
LC Kim, Y Hwang, W Song, RS Cook, J Chen
Cancer Research 79 (13_Supplement), 3434-3434, 2019
12019
Cancer-associated fibroblasts maintain critical pancreatic cancer cell lipid homeostasis in the tumor microenvironment
X Han, M Burrows, LC Kim, JP Xu, W Vostrejs, TN Van Le, C Poltorack, ...
Cell reports 43 (11), 2024
2024
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Artiklar 1–20