Developing covalent protein drugs via proximity-enabled reactive therapeutics Q Li, Q Chen, PC Klauser, M Li, F Zheng, N Wang, X Li, Q Zhang, X Fu, ... Cell 182 (1), 85-97. e16, 2020 | 157 | 2020 |
DNA-catalyzed amide hydrolysis C Zhou, JL Avins, PC Klauser, BM Brandsen, Y Lee, SK Silverman Journal of the American Chemical Society 138 (7), 2106-2109, 2016 | 83 | 2016 |
A Genetically Encoded Fluorosulfonyloxybenzoyl-l-lysine for Expansive Covalent Bonding of Proteins via SuFEx Chemistry J Liu, L Cao, PC Klauser, R Cheng, VY Berdan, W Sun, N Wang, ... Journal of the American Chemical Society 143 (27), 10341-10351, 2021 | 76 | 2021 |
Covalent peptides and proteins for therapeutics VY Berdan, PC Klauser, L Wang Bioorganic & Medicinal Chemistry 29, 115896, 2021 | 51 | 2021 |
Genetically encoded quinone methides enabling rapid, site-specific, and photocontrolled protein modification with amine reagents J Liu, R Cheng, N Van Eps, N Wang, T Morizumi, WL Ou, PC Klauser, ... Journal of the American Chemical Society 142 (40), 17057-17068, 2020 | 37 | 2020 |
DNA-catalyzed DNA cleavage by a radical pathway with well-defined products Y Lee, PC Klauser, BM Brandsen, C Zhou, X Li, SK Silverman Journal of the American Chemical Society 139 (1), 255-261, 2017 | 26 | 2017 |
Covalent proteins as targeted radionuclide therapies enhance antitumor effects PC Klauser, S Chopra, L Cao, KN Bobba, B Yu, Y Seo, E Chan, ... ACS central science 9 (6), 1241-1251, 2023 | 21 | 2023 |
The proximity-enabled sulfur fluoride exchange reaction in the protein context B Yu, L Cao, S Li, PC Klauser, L Wang Chemical Science 14 (29), 7913-7921, 2023 | 14 | 2023 |
Encoding latent SuFEx reactive meta-fluorosulfate tyrosine to expand covalent bonding of proteins PC Klauser, VY Berdan, L Cao, L Wang Chemical Communications 58 (48), 6861-6864, 2022 | 12 | 2022 |
Arginine accelerates sulfur fluoride exchange and phosphorus fluoride exchange reactions between proteins L Cao, B Yu, PC Klauser, P Zhang, S Li, L Wang Angewandte Chemie 136 (47), e202412843, 2024 | 3 | 2024 |
Bioreactive proteins containing unnatural amino acids L Wang, W Sun, PC Klauser, L Cao, YU Bingchen, N Wang, S Li, ... US Patent App. 18/288,679, 2024 | | 2024 |
Developing Covalent Biologics Through Genetic Code Expansion for Cancer Therapeutics PC Klauser University of California, San Francisco, 2023 | | 2023 |