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Paul C. Klauser
Paul C. Klauser
Verifierad e-postadress på mskcc.org
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Developing covalent protein drugs via proximity-enabled reactive therapeutics
Q Li, Q Chen, PC Klauser, M Li, F Zheng, N Wang, X Li, Q Zhang, X Fu, ...
Cell 182 (1), 85-97. e16, 2020
1572020
DNA-catalyzed amide hydrolysis
C Zhou, JL Avins, PC Klauser, BM Brandsen, Y Lee, SK Silverman
Journal of the American Chemical Society 138 (7), 2106-2109, 2016
832016
A Genetically Encoded Fluorosulfonyloxybenzoyl-l-lysine for Expansive Covalent Bonding of Proteins via SuFEx Chemistry
J Liu, L Cao, PC Klauser, R Cheng, VY Berdan, W Sun, N Wang, ...
Journal of the American Chemical Society 143 (27), 10341-10351, 2021
762021
Covalent peptides and proteins for therapeutics
VY Berdan, PC Klauser, L Wang
Bioorganic & Medicinal Chemistry 29, 115896, 2021
512021
Genetically encoded quinone methides enabling rapid, site-specific, and photocontrolled protein modification with amine reagents
J Liu, R Cheng, N Van Eps, N Wang, T Morizumi, WL Ou, PC Klauser, ...
Journal of the American Chemical Society 142 (40), 17057-17068, 2020
372020
DNA-catalyzed DNA cleavage by a radical pathway with well-defined products
Y Lee, PC Klauser, BM Brandsen, C Zhou, X Li, SK Silverman
Journal of the American Chemical Society 139 (1), 255-261, 2017
262017
Covalent proteins as targeted radionuclide therapies enhance antitumor effects
PC Klauser, S Chopra, L Cao, KN Bobba, B Yu, Y Seo, E Chan, ...
ACS central science 9 (6), 1241-1251, 2023
212023
The proximity-enabled sulfur fluoride exchange reaction in the protein context
B Yu, L Cao, S Li, PC Klauser, L Wang
Chemical Science 14 (29), 7913-7921, 2023
142023
Encoding latent SuFEx reactive meta-fluorosulfate tyrosine to expand covalent bonding of proteins
PC Klauser, VY Berdan, L Cao, L Wang
Chemical Communications 58 (48), 6861-6864, 2022
122022
Arginine accelerates sulfur fluoride exchange and phosphorus fluoride exchange reactions between proteins
L Cao, B Yu, PC Klauser, P Zhang, S Li, L Wang
Angewandte Chemie 136 (47), e202412843, 2024
32024
Bioreactive proteins containing unnatural amino acids
L Wang, W Sun, PC Klauser, L Cao, YU Bingchen, N Wang, S Li, ...
US Patent App. 18/288,679, 2024
2024
Developing Covalent Biologics Through Genetic Code Expansion for Cancer Therapeutics
PC Klauser
University of California, San Francisco, 2023
2023
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Artiklar 1–12