The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer M Heger, RF van Golen, M Broekgaarden, MC Michel, DR Sibley Pharmacological reviews 66 (1), 222-307, 2014 | 629 | 2014 |
Tumor cell survival pathways activated by photodynamic therapy: a molecular basis for pharmacological inhibition strategies M Broekgaarden, R Weijer, TM van Gulik, MR Hamblin, M Heger Cancer and Metastasis Reviews 34, 643-690, 2015 | 257 | 2015 |
Photonanomedicine: a convergence of photodynamic therapy and nanotechnology G Obaid, M Broekgaarden, AL Bulin, HC Huang, J Kuriakose, J Liu, ... Nanoscale 8 (25), 12471-12503, 2016 | 197 | 2016 |
Enhancing photodynamic therapy of refractory solid cancers: Combining second-generation photosensitizers with multi-targeted liposomal delivery R Weijer, M Broekgaarden, M Kos, R van Vught, EAJ Rauws, E Breukink, ... Journal of Photochemistry and Photobiology C: Photochemistry Reviews 23, 103-131, 2015 | 153 | 2015 |
Microbial production of natural raspberry ketone J Beekwilder, IM Van der Meer, O Sibbesen, M Broekgaarden, I Qvist, ... Biotechnology Journal: Healthcare Nutrition Technology 2 (10), 1270-1279, 2007 | 142 | 2007 |
Preparation and practical applications of 2′, 7′-dichlorodihydrofluorescein in redox assays MJ Reiniers, RF van Golen, S Bonnet, M Broekgaarden, TM van Gulik, ... Analytical chemistry 89 (7), 3853-3857, 2017 | 104 | 2017 |
Inhibition of hypoxia-inducible factor 1 with acriflavine sensitizes hypoxic tumor cells to photodynamic therapy with zinc phthalocyanine-encapsulating cationic liposomes M Broekgaarden, R Weijer, M Krekorian, B van den IJssel, M Kos, ... Nano Research, 1-24, 2016 | 93 | 2016 |
Impacting Pancreatic Cancer Therapy in Heterotypic in Vitro Organoids and in Vivo Tumors with Specificity-Tuned, NIR-Activable Photoimmunonanoconjugates … G Obaid, S Bano, S Mallidi, M Broekgaarden, J Kuriakose, Z Silber, ... Nano letters 19 (11), 7573-7587, 2019 | 86 | 2019 |
An overview of three promising mechanical, optical, and biochemical engineering approaches to improve selective photothermolysis of refractory port wine stains G Aguilar, B Choi, M Broekgaarden, O Yang, B Yang, P Ghasri, JK Chen, ... Annals of biomedical engineering 40, 486-506, 2012 | 79 | 2012 |
Inhibition of hypoxia inducible factor 1 and topoisomerase with acriflavine sensitizes perihilar cholangiocarcinomas to photodynamic therapy R Weijer, M Broekgaarden, M Krekorian, LK Alles, AC van Wijk, ... Oncotarget 7 (3), 3341, 2015 | 69 | 2015 |
Modulation of redox metabolism negates cancer-associated fibroblasts-induced treatment resistance in a heterotypic 3D culture platform of pancreatic cancer M Broekgaarden, S Anbil, AL Bulin, G Obaid, Z Mai, Y Baglo, I Rizvi, ... Biomaterials 222, 119421, 2019 | 68 | 2019 |
Development and in vitro proof-of-concept of interstitially targeted zinc-phthalocyanine liposomes for photodynamic therapy M Broekgaarden, A IPM de Kroon, T M van Gulik, M Heger Current medicinal chemistry 21 (3), 377-391, 2014 | 65 | 2014 |
Comprehensive high-throughput image analysis for therapeutic efficacy of architecturally complex heterotypic organoids AL Bulin, M Broekgaarden, T Hasan Scientific reports 7 (1), 16645, 2017 | 61 | 2017 |
Radiation dose‐enhancement is a potent radiotherapeutic effect of rare‐earth composite nanoscintillators in preclinical models of glioblastoma AL Bulin, M Broekgaarden, F Chaput, V Baisamy, J Garrevoet, B Busser, ... Advanced Science 7 (20), 2001675, 2020 | 60 | 2020 |
Photodynamic therapy with liposomal zinc phthalocyanine and tirapazamine increases tumor cell death via DNA damage M Broekgaarden, R Weijer, AC van Wijk, RC Cox, MR Egmond, R Hoebe, ... Journal of biomedical nanotechnology 13 (2), 204-220, 2017 | 50 | 2017 |
Site-specific conjugation of single domain antibodies to liposomes enhances photosensitizer uptake and photodynamic therapy efficacy M Broekgaarden, R Van Vught, S Oliveira, RC Roovers, ... Nanoscale 8 (12), 6490-6494, 2016 | 45 | 2016 |
Neoadjuvant photodynamic therapy augments immediate and prolonged oxaliplatin efficacy in metastatic pancreatic cancer organoids M Broekgaarden, I Rizvi, AL Bulin, L Petrovic, R Goldschmidt, I Massodi, ... Oncotarget 9 (16), 13009, 2018 | 44 | 2018 |
Low dose photodynamic therapy harmonizes with radiation therapy to induce beneficial effects on pancreatic heterocellular spheroids AL Bulin, M Broekgaarden, D Simeone, T Hasan Oncotarget 10 (27), 2625, 2019 | 42 | 2019 |
Vitamin D receptor activation and photodynamic priming enables durable low-dose chemotherapy S Anbil, M Pigula, HC Huang, S Mallidi, M Broekgaarden, Y Baglo, ... Molecular cancer therapeutics 19 (6), 1308-1319, 2020 | 41 | 2020 |
Aza-BODIPY: A new vector for enhanced theranostic boron neutron capture therapy applications G Kalot, A Godard, B Busser, J Pliquett, M Broekgaarden, V Motto-Ros, ... Cells 9 (9), 1953, 2020 | 40 | 2020 |