| Antibacterial approaches in tissue engineering using metal ions and nanoparticles: From mechanisms to applications M Godoy-Gallardo, U Eckhard, LM Delgado, YJD de Roo Puente, ... Bioactive Materials 6 (12), 4470-4490, 2021 | 660 | 2021 |
| Active site specificity profiling of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic … U Eckhard, PF Huesgen, O Schilling, CL Bellac, GS Butler, JH Cox, ... Matrix biology 49, 37-60, 2016 | 228 | 2016 |
| Proteolytic Cleavage Mechanisms, Function, and “Omic” Approaches for a Near-Ubiquitous Posttranslational Modification T Klein, U Eckhard, A Dufour, N Solis, CM Overall Chemical reviews 118 (3), 1137-1168, 2018 | 206 | 2018 |
| LysargiNase mirrors trypsin for protein C-terminal and methylation-site identification PF Huesgen, PF Lange, LD Rogers, N Solis, U Eckhard, O Kleifeld, ... Nature methods 12 (1), 55-58, 2015 | 161 | 2015 |
| Structure of collagenase G reveals a chew-and-digest mechanism of bacterial collagenolysis U Eckhard, E Schönauer, D Nüss, H Brandstetter Nature structural & molecular biology 18 (10), 1109-1114, 2011 | 144 | 2011 |
| Crystallographically mapped ligand binding differs in high and low IgE binding isoforms of birch pollen allergen bet v 1 S Kofler, C Asam, U Eckhard, M Wallner, F Ferreira, H Brandstetter Journal of molecular biology 422 (1), 109-123, 2012 | 127 | 2012 |
| Protein termini and their modifications revealed by positional proteomics G Marino, U Eckhard, CM Overall ACS chemical biology 10 (8), 1754-1764, 2015 | 122 | 2015 |
| Structural basis for activity regulation and substrate preference of clostridial collagenases G, H, and T U Eckhard, E Schönauer, H Brandstetter Journal of Biological Chemistry 288 (28), 20184-20194, 2013 | 121 | 2013 |
| Proteomic protease specificity profiling of clostridial collagenases reveals their intrinsic nature as dedicated degraders of collagen U Eckhard, PF Huesgen, H Brandstetter, CM Overall Journal of proteomics 100, 102-114, 2014 | 113 | 2014 |
| Systems-level analysis of proteolytic events in increased vascular permeability and complement activation in skin inflammation U Auf dem Keller, A Prudova, U Eckhard, B Fingleton, CM Overall Science signaling 6 (258), rs2-rs2, 2013 | 113 | 2013 |
| C-terminal truncation of IFN-γ inhibits proinflammatory macrophage responses and is deficient in autoimmune disease A Dufour, CL Bellac, U Eckhard, N Solis, T Klein, R Kappelhoff, N Fortelny, ... Nature Communications 9 (1), 2416, 2018 | 84 | 2018 |
| TAILS N-terminomics and proteomics show protein degradation dominates over proteolytic processing by cathepsins in pancreatic tumors A Prudova, V Gocheva, U Auf dem Keller, U Eckhard, OC Olson, L Akkari, ... Cell reports 16 (6), 1762-1773, 2016 | 82 | 2016 |
| Cleavage specificity analysis of six type II transmembrane serine proteases (TTSPs) using PICS with proteome-derived peptide libraries O Barre, A Dufour, U Eckhard, R Kappelhoff, F Beliveau, R Leduc, ... PLoS One 9 (9), e105984, 2014 | 71 | 2014 |
| TAILS N-terminomics of human platelets reveals pervasive metalloproteinase-dependent proteolytic processing in storage A Prudova, K Serrano, U Eckhard, N Fortelny, DV Devine, CM Overall Blood, The Journal of the American Society of Hematology 124 (26), e49-e60, 2014 | 70 | 2014 |
| Positional proteomics in the era of the human proteome project on the doorstep of precision medicine U Eckhard, G Marino, GS Butler, CM Overall Biochimie 122, 110-118, 2016 | 62 | 2016 |
| Biochemical characterization of the catalytic domains of three different Clostridial collagenases U Eckhard, E Schönauer, P Ducka, P Briza, D Nüss, H Brandstetter Biological chemistry 390 (1), 11-18, 2009 | 59 | 2009 |
| The human dental pulp proteome and N-terminome: levering the unexplored potential of semitryptic peptides enriched by TAILS to identify missing proteins in the human proteome … U Eckhard, G Marino, SR Abbey, G Tharmarajah, I Matthew, CM Overall Journal of proteome research 14 (9), 3568-3582, 2015 | 58 | 2015 |
| An Introduction to Bacterial Biofilms and Their Proteases, and Their Roles in Host Infection and Immune Evasion JS Ramírez-Larrota, U Eckhard Biomolecules 12 (2), 306, 2022 | 53 | 2022 |
| Discovery of a proteolytic flagellin family in diverse bacterial phyla that assembles enzymatically active flagella U Eckhard, H Bandukwala, MJ Mansfield, G Marino, J Cheng, I Wallace, ... Nature communications 8 (1), 521, 2017 | 47 | 2017 |
| Family-wide characterization of matrix metalloproteinases from Arabidopsis thaliana reveals their distinct proteolytic activity and cleavage site specificity G Marino, PF Huesgen, U Eckhard, CM Overall, WP Schröder, C Funk Biochemical Journal 457 (2), 335-346, 2014 | 47 | 2014 |
Christopher M OverallUniversity of British ColumbiaVerifierad e-postadress på ubc.ca