| A review of metal‐catalyzed molecular damage: protection by melatonin A Romero, E Ramos, C de Los Rios, J Egea, J Del Pino, RJ Reiter Journal of Pineal Research 56 (4), 343-370, 2014 | 192 | 2014 |
| Tacripyrines, the first tacrine− dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer’s disease J Marco-Contelles, R León, C De Los Ríos, A Samadi, M Bartolini, ... Journal of medicinal chemistry 52 (9), 2724-2732, 2009 | 177 | 2009 |
| Novel Multipotent Tacrine− Dihydropyridine Hybrids with Improved Acetylcholinesterase Inhibitory and Neuroprotective Activities as Potential Drugs for the Treatment of … J Marco-Contelles, R León, C de Los Ríos, A Guglietta, J Terencio, ... Journal of medicinal chemistry 49 (26), 7607-7610, 2006 | 149 | 2006 |
| Ischemic brain injury: New insights on the protective role of melatonin E Ramos, P Patiño, RJ Reiter, E Gil-Martín, J Marco-Contelles, E Parada, ... Free Radical Biology and Medicine 104, 32-53, 2017 | 113 | 2017 |
| New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties R León, C de los Ríos, J Marco-Contelles, O Huertas, X Barril, FJ Luque, ... Bioorganic & medicinal chemistry 16 (16), 7759-7769, 2008 | 101 | 2008 |
| Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted … A Samadi, C De Los Ríos, I Bolea, M Chioua, I Iriepa, I Moraleda, ... European journal of medicinal chemistry 52, 251-262, 2012 | 93 | 2012 |
| Synthesis, biological assessment and molecular modeling of new multipotent MAO and cholinesterase inhibitors as potential drugs for the treatment of Alzheimer’s disease A Samadi, M Chioua, I Bolea, C De Los Ríos, I Iriepa, I Moraleda, ... European journal of medicinal chemistry 46 (9), 4665-4668, 2011 | 85 | 2011 |
| Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1, 8-naphthyridine derivatives C De Los Ríos, J Egea, J Marco-Contelles, R León, A Samadi, I Iriepa, ... Journal of medicinal chemistry 53 (14), 5129-5143, 2010 | 83 | 2010 |
| Synthesis, biological assessment, and molecular modeling of racemic 7-aryl-9, 10, 11, 12-tetrahydro-7H-benzo [7, 8] chromeno [2, 3-b] quinolin-8-amines as potential drugs for … E Maalej, F Chabchoub, MJ Oset-Gasque, M Esquivias-Pérez, ... European journal of medicinal chemistry 54, 750-763, 2012 | 81 | 2012 |
| Synthesis, biological assessment and molecular modeling of new dihydroquinoline-3-carboxamides and dihydroquinoline-3-carbohydrazide derivatives as cholinesterase inhibitors … I Tomassoli, L Ismaili, M Pudlo, C de Los Ríos, E Soriano, I Colmena, ... European journal of medicinal chemistry 46 (1), 1-10, 2011 | 71 | 2011 |
| New multipotent tetracyclic tacrines with neuroprotective activity J Marco-Contelles, R León, C de los Ríos, AG García, MG López, ... Bioorganic & medicinal chemistry 14 (24), 8176-8185, 2006 | 69 | 2006 |
| Cholinergic and neuroprotective drugs for the treatment of Alzheimer and neuronal vascular diseases. II. Synthesis, biological assessment, and molecular modelling of new … A Samadi, C Valderas, C De Los Ríos, A Bastida, M Chioua, ... Bioorganic & medicinal chemistry 19 (1), 122-133, 2011 | 68 | 2011 |
| The purinergic P2X7 receptor as a potential drug target to combat neuroinflammation in neurodegenerative diseases F Calzaferri, C Ruiz‐Ruiz, AMG de Diego, R de Pascual, I Méndez‐López, ... Medicinal research reviews 40 (6), 2427-2465, 2020 | 65 | 2020 |
| Synthesis and pharmacological assessment of diversely substituted pyrazolo [3, 4-b] quinoline, and benzo [b] pyrazolo [4, 3-g][1, 8] naphthyridine derivatives D Silva, M Chioua, A Samadi, MC Carreiras, ML Jimeno, E Mendes, ... European journal of medicinal chemistry 46 (9), 4676-4681, 2011 | 64 | 2011 |
| Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer and neuronal vascular diseases. I. Synthesis, biological assessment, and … A Samadi, J Marco-Contelles, E Soriano, M Álvarez-Pérez, M Chioua, ... Bioorganic & medicinal chemistry 18 (16), 5861-5872, 2010 | 64 | 2010 |
| Synthesis and biological assessment of diversely substituted furo [2, 3-b] quinolin-4-amine and pyrrolo [2, 3-b] quinolin-4-amine derivatives, as novel tacrine analogues C Martins, MC Carreiras, R León, C De Los Ríos, M Bartolini, V Andrisano, ... European journal of medicinal chemistry 46 (12), 6119-6130, 2011 | 63 | 2011 |
| Synthesis, pharmacological assessment, and molecular modeling of acetylcholinesterase/butyrylcholinesterase inhibitors: effect against amyloid-β-induced neurotoxicity D Silva, M Chioua, A Samadi, P Agostinho, P Garcao, R Lajarín-Cuesta, ... ACS Chemical Neuroscience 4 (4), 547-565, 2013 | 56 | 2013 |
| Tacrines for Alzheimer's disease therapy. III. The PyridoTacrines C de Los Ríos, J Marco-Contelles European journal of medicinal chemistry 166, 381-389, 2019 | 49 | 2019 |
| Synthesis of 6-amino-1, 4-dihydropyridines that prevent calcium overload and neuronal death R León, C de Los Ríos, J Marco-Contelles, MG López, AG García, ... European journal of medicinal chemistry 43 (3), 668-674, 2008 | 49 | 2008 |
| syntheses and reactions of optically active α-Aminoallenylstannanes PBD Ranslow, LS Hegedus, C de los Rios The Journal of Organic Chemistry 69 (1), 105-111, 2004 | 47 | 2004 |
