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Xander Wehrens, MD PhD
Xander Wehrens, MD PhD
Director, Cardiovascular Research Institute, Baylor College of Medicine
Verifierad e-postadress på bcm.edu - Startsida
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FKBP12. 6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death
XHT Wehrens, SE Lehnart, F Huang, JA Vest, SR Reiken, PJ Mohler, ...
Cell 113 (7), 829-840, 2003
9322003
Impact of noncardiac comorbidities on morbidity and mortality in a predominantly male population with heart failure and preserved versus reduced ejection fraction
S Ather, W Chan, B Bozkurt, D Aguilar, K Ramasubbu, AA Zachariah, ...
Journal of the American college of cardiology 59 (11), 998-1005, 2012
8682012
Ca2+/Calmodulin-Dependent Protein Kinase II Phosphorylation Regulates the Cardiac Ryanodine Receptor
XHT Wehrens, SE Lehnart, SR Reiken, AR Marks
Circulation research 94 (6), e61-e70, 2004
8162004
Enhanced Sarcoplasmic Reticulum Ca2+ Leak and Increased Na+-Ca2+ Exchanger Function Underlie Delayed Afterdepolarizations in Patients With Chronic …
N Voigt, N Li, Q Wang, W Wang, AW Trafford, I Abu-Taha, Q Sun, ...
Circulation 125 (17), 2059-2070, 2012
6892012
Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias
SE Lehnart, XHT Wehrens, S Reiken, S Warrier, AE Belevych, RD Harvey, ...
Cell 123 (1), 25-35, 2005
6052005
Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2
XHT Wehrens, SE Lehnart, SR Reiken, SX Deng, JA Vest, D Cervantes, ...
Science 304 (5668), 292-296, 2004
5952004
Calcium signaling and cardiac arrhythmias
AP Landstrom, D Dobrev, XHT Wehrens
Circulation research 120 (12), 1969-1993, 2017
5572017
Enhanced cardiomyocyte NLRP3 inflammasome signaling promotes atrial fibrillation
C Yao, T Veleva, L Scott Jr, S Cao, L Li, G Chen, P Jeyabal, X Pan, ...
Circulation 138 (20), 2227-2242, 2018
5422018
Cellular and molecular mechanisms of atrial arrhythmogenesis in patients with paroxysmal atrial fibrillation
N Voigt, J Heijman, Q Wang, DY Chiang, N Li, M Karck, XHT Wehrens, ...
Circulation 129 (2), 145-156, 2014
5352014
Evidence for multiple mechanisms in human ventricular fibrillation
MP Nash, A Mourad, RH Clayton, PM Sutton, CP Bradley, M Hayward, ...
Circulation 114 (6), 536-542, 2006
491*2006
Calmodulin kinase II–mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice
MG Chelu, S Sarma, S Sood, S Wang, RJ Van Oort, DG Skapura, N Li, ...
The Journal of clinical investigation 119 (7), 1940-1951, 2009
4732009
Intracellular calcium release and cardiac disease
XHT Wehrens, SE Lehnart, AR Marks
Annual review of physiology 67, 69, 2005
4402005
Defective cardiac ryanodine receptor regulation during atrial fibrillation
JA Vest, XHT Wehrens, SR Reiken, SE Lehnart, D Dobrev, P Chandra, ...
Circulation 111 (16), 2025-2032, 2005
4382005
Ryanodine receptor/calcium release channel PKA phosphorylation: a critical mediator of heart failure progression
XHT Wehrens, SE Lehnart, S Reiken, JA Vest, A Wronska, AR Marks
Proceedings of the National Academy of Sciences 103 (3), 511-518, 2006
4332006
β-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure
S Reiken, XHT Wehrens, JA Vest, A Barbone, S Klotz, D Mancini, ...
Circulation 107 (19), 2459-2466, 2003
4322003
Circadian rhythms govern cardiac repolarization and arrhythmogenesis
D Jeyaraj, SM Haldar, X Wan, MD McCauley, JA Ripperger, K Hu, Y Lu, ...
Nature 483 (7387), 96-99, 2012
4142012
Sudden death in familial polymorphic ventricular tachycardia associated with calcium release channel (ryanodine receptor) leak
SE Lehnart, XHT Wehrens, PJ Laitinen, SR Reiken, SX Deng, Z Cheng, ...
Circulation 109 (25), 3208-3214, 2004
3912004
Transverse aortic constriction in mice
CA Angela, RJ van Oort, XHT Wehrens
Journal of visualized experiments: JoVE, 1729, 2010
3852010
Oxidized Ca2+/Calmodulin-Dependent Protein Kinase II Triggers Atrial Fibrillation
A Purohit, AG Rokita, X Guan, B Chen, OM Koval, N Voigt, S Neef, T Sowa, ...
Circulation 128 (16), 1748-1757, 2013
3592013
Evidence for multiple mechanisms in human ventricular fibrillation
MP Nash, A Mourad, RH Clayton, PM Sutton, CP Bradley, M Hayward, ...
Circulation 114 (6), 536-542, 2006
3592006
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