Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α M Lagouge, C Argmann, Z Gerhart-Hines, H Meziane, C Lerin, F Daussin, ... Cell 127 (6), 1109-1122, 2006 | 4888 | 2006 |
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity C Cantó, Z Gerhart-Hines, JN Feige, M Lagouge, L Noriega, JC Milne, ... Nature 458 (7241), 1056-1060, 2009 | 3623 | 2009 |
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC‐1α Z Gerhart‐Hines, JT Rodgers, O Bare, C Lerin, SH Kim, R Mostoslavsky, ... The EMBO journal 26 (7), 1913-1923, 2007 | 1510 | 2007 |
Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment ZT Schafer, AR Grassian, L Song, Z Jiang, Z Gerhart-Hines, HY Irie, ... Nature 461 (7260), 109-113, 2009 | 1158 | 2009 |
Metabolic adaptations through the PGC-1α and SIRT1 pathways JT Rodgers, C Lerin, Z Gerhart-Hines, P Puigserver FEBS letters 582 (1), 46-53, 2008 | 747 | 2008 |
The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD+ Z Gerhart-Hines, JE Dominy, SM Blättler, MP Jedrychowski, AS Banks, ... Molecular cell 44 (6), 851-863, 2011 | 373 | 2011 |
The nuclear receptor Rev-erbα controls circadian thermogenic plasticity Z Gerhart-Hines, D Feng, MJ Emmett, LJ Everett, E Loro, ER Briggs, ... Nature 503 (7476), 410-413, 2013 | 294 | 2013 |
A metabolic prosurvival role for PML in breast cancer A Carracedo, D Weiss, AK Leliaert, M Bhasin, VCJ De Boer, G Laurent, ... The Journal of clinical investigation 122 (9), 3088-3100, 2012 | 288 | 2012 |
Kynurenic acid and Gpr35 regulate adipose tissue energy homeostasis and inflammation LZ Agudelo, DMS Ferreira, I Cervenka, G Bryzgalova, S Dadvar, ... Cell metabolism 27 (2), 378-392. e5, 2018 | 260 | 2018 |
Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1α complex JH Lim, Z Gerhart-Hines, JE Dominy, Y Lee, S Kim, M Tabata, YK Xiang, ... Journal of Biological Chemistry 288 (10), 7117-7126, 2013 | 250 | 2013 |
Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo B Fang, LJ Everett, J Jager, E Briggs, SM Armour, D Feng, A Roy, ... Cell 159 (5), 1140-1152, 2014 | 235 | 2014 |
Nutrient-dependent regulation of PGC-1α's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5 JE Dominy Jr, Y Lee, Z Gerhart-Hines, P Puigserver Biochimica et biophysica acta (BBA)-proteins and proteomics 1804 (8), 1676-1683, 2010 | 226 | 2010 |
Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells G Suchankova, LE Nelson, Z Gerhart-Hines, M Kelly, MS Gauthier, ... Biochemical and biophysical research communications 378 (4), 836-841, 2009 | 215 | 2009 |
Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge MJ Emmett, HW Lim, J Jager, HJ Richter, M Adlanmerini, LC Peed, ... Nature 546 (7659), 544-548, 2017 | 187 | 2017 |
Circadian metabolism in the light of evolution Z Gerhart-Hines, MA Lazar Endocrine reviews 36 (3), 289-304, 2015 | 187 | 2015 |
Cardiolipin synthesis in brown and beige fat mitochondria is essential for systemic energy homeostasis EG Sustarsic, T Ma, MD Lynes, M Larsen, I Karavaeva, JF Havelund, ... Cell metabolism 28 (1), 159-174. e11, 2018 | 162 | 2018 |
Proteomics-based comparative mapping of the secretomes of human brown and white adipocytes reveals EPDR1 as a novel batokine AS Deshmukh, L Peijs, JL Beaudry, NZ Jespersen, CH Nielsen, T Ma, ... Cell Metabolism 30 (5), 963-975. e7, 2019 | 152 | 2019 |
Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling E Khatib-Massalha, S Bhattacharya, H Massalha, A Biram, K Golan, ... Nature Communications 11 (1), 3547, 2020 | 126 | 2020 |
A diurnal rhythm in brown adipose tissue causes rapid clearance and combustion of plasma lipids at wakening R van den Berg, S Kooijman, R Noordam, A Ramkisoensing, ... Cell reports 22 (13), 3521-3533, 2018 | 105 | 2018 |
Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis OS Johansen, T Ma, JB Hansen, LK Markussen, R Schreiber, ... Cell 184 (13), 3502-3518. e33, 2021 | 101 | 2021 |