| A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids JA Chavez, TA Knotts, LP Wang, G Li, RT Dobrowsky, GL Florant, ... Journal of Biological Chemistry 278 (12), 10297-10303, 2003 | 739 | 2003 |
| GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates SE Mullican, X Lin-Schmidt, CN Chin, JA Chavez, JL Furman, ... Nature medicine 23 (10), 1150-1157, 2017 | 701 | 2017 |
| A ceramide-centric view of insulin resistance JA Chavez, SA Summers Cell metabolism 15 (5), 585-594, 2012 | 695 | 2012 |
| Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes JA Chavez, SA Summers Archives of biochemistry and biophysics 419 (2), 101-109, 2003 | 606 | 2003 |
| Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane H Sano, L Eguez, MN Teruel, M Fukuda, TD Chuang, JA Chavez, ... Cell metabolism 5 (4), 293-303, 2007 | 433 | 2007 |
| Full intracellular retention of GLUT4 requires AS160 Rab GTPase activating protein L Eguez, A Lee, JA Chavez, CP Miinea, S Kane, GE Lienhard, ... Cell metabolism 2 (4), 263-272, 2005 | 417 | 2005 |
| Lipid mediators of insulin resistance WL Holland, TA Knotts, JA Chavez, LP Wang, KL Hoehn, SA Summers Nutrition reviews 65 (suppl_1), S39-S46, 2007 | 375 | 2007 |
| Acid ceramidase overexpression prevents the inhibitory effects of saturated fatty acids on insulin signaling JA Chavez, WL Holland, J Bär, K Sandhoff, SA Summers Journal of Biological Chemistry 280 (20), 20148-20153, 2005 | 275 | 2005 |
| Substrate specificity and effect on GLUT4 translocation of the Rab GTPase-activating protein Tbc1d1 WG Roach, JA Chavez, CP Mîinea, GE Lienhard Biochemical Journal 403 (2), 353-358, 2007 | 243 | 2007 |
| Lipid oversupply, selective insulin resistance, and lipotoxicity: molecular mechanisms JA Chavez, SA Summers Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2010 | 202 | 2010 |
| Inhibition of GLUT4 translocation by Tbc1d1, a Rab GTPase-activating protein abundant in skeletal muscle, is partially relieved by AMP-activated protein kinase activation JA Chavez, WG Roach, SR Keller, WS Lane, GE Lienhard Journal of Biological Chemistry 283 (14), 9187-9195, 2008 | 200 | 2008 |
| Ceramides and glucosylceramides are independent antagonists of insulin signaling JA Chavez, MM Siddique, ST Wang, J Ching, JA Shayman, SA Summers Journal of Biological Chemistry 289 (2), 723-734, 2014 | 169 | 2014 |
| Insulin-stimulated phosphorylation of the Rab GTPase-activating protein TBC1D1 regulates GLUT4 translocation GR Peck, JA Chavez, WG Roach, BA Budnik, WS Lane, HKR Karlsson, ... Journal of Biological Chemistry 284 (44), 30016-30023, 2009 | 113 | 2009 |
| Effect of a membrane-targeted sphingosine kinase 1 on cell proliferation and survival F Safadi-Chamberlain, LP Wang, SG Payne, CU Lim, S Stratford, ... Biochemical Journal 388 (3), 827-834, 2005 | 29 | 2005 |
| Adipocytes contain a novel complex similar to the tuberous sclerosis complex S Gridley, JA Chavez, WS Lane, GE Lienhard Cellular signalling 18 (10), 1626-1632, 2006 | 26 | 2006 |
| The 47 kDa Akt substrate associates with phosphodiesterase 3B and regulates its level in adipocytes JA Chavez, S Gridley, H Sano, WS Lane, GE Lienhard Biochemical and biophysical research communications 342 (4), 1218-1222, 2006 | 20 | 2006 |
| GDF15 fusion proteins and uses thereof A Armstrong, JA Connor, J Furman, C Huang, MJ Hunter, X Lin-Schmidt, ... US Patent 10,336,812, 2019 | 11 | 2019 |
| GDF15 fusion proteins and uses thereof A Armstrong, JA Connor, J Furman, C Huang, MJ Hunter, X Lin-Schmidt, ... US Patent 11,208,464, 2021 | 7 | 2021 |
| Constraining Stellar Rotation at the Zero-age Main Sequence with TESS ST Douglas, PA Cargile, SP Matt, AA Breimann, JAP Chávez, CX Huang, ... The Astrophysical Journal 962 (1), 16, 2024 | 6 | 2024 |
| Growth differentiation factor-15 (GDF-15) inhibits gastric emptying in rodents as part of its anorectic mechanism of action SA Hinke, CR Cavanaugh, T Kirchner, W Lang, R Meng, NH Wallace, ... Diabetes 67 (Supplement_1), 2018 | 6 | 2018 |
Scott A. SummersUniversity of UtahVerifierad e-postadress på health.utah.edu
