| Nanog safeguards pluripotency and mediates germline development I Chambers, J Silva, D Colby, J Nichols, B Nijmeijer, M Robertson, ... Nature 450 (7173), 1230-1234, 2007 | 1825 | 2007 |
| Nanog is the gateway to the pluripotent ground state J Silva, J Nichols, TW Theunissen, G Guo, AL van Oosten, O Barrandon, ... Cell 138 (4), 722-737, 2009 | 1281 | 2009 |
| Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation M De Napoles, JE Mermoud, R Wakao, YA Tang, M Endoh, R Appanah, ... Developmental cell 7 (5), 663-676, 2004 | 1120 | 2004 |
| Promotion of reprogramming to ground state pluripotency by signal inhibition J Silva, O Barrandon, J Nichols, J Kawaguchi, TW Theunissen, A Smith PLoS biology 6 (10), e253, 2008 | 1061 | 2008 |
| Capture of authentic embryonic stem cells from rat blastocysts M Buehr, S Meek, K Blair, J Yang, J Ure, J Silva, R McLay, J Hall, QL Ying, ... Cell 135 (7), 1287-1298, 2008 | 973 | 2008 |
| Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes J Silva, W Mak, I Zvetkova, R Appanah, TB Nesterova, Z Webster, ... Developmental cell 4 (4), 481-495, 2003 | 801 | 2003 |
| Senescence impairs successful reprogramming to pluripotent stem cells A Banito, ST Rashid, JC Acosta, SD Li, CF Pereira, I Geti, S Pinho, ... Genes & development 23 (18), 2134-2139, 2009 | 728 | 2009 |
| Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo J Nichols, J Silva, M Roode, A Smith Development 136 (19), 3215-3222, 2009 | 696 | 2009 |
| Capturing pluripotency J Silva, A Smith Cell 132 (4), 532-536, 2008 | 597 | 2008 |
| NANOG-dependent function of TET1 and TET2 in establishment of pluripotency Y Costa, J Ding, TW Theunissen, F Faiola, TA Hore, PV Shliaha, ... Nature, 2013 | 483 | 2013 |
| Nanog promotes transfer of pluripotency after cell fusion J Silva, I Chambers, S Pollard, A Smith Nature 441 (7096), 997-1001, 2006 | 463 | 2006 |
| Citrullination regulates pluripotency and histone H1 binding to chromatin MA Christophorou, G Castelo-Branco, RP Halley-Stott, CS Oliveira, ... Nature 507 (7490), 104-108, 2014 | 440 | 2014 |
| Stat3 activation is limiting for reprogramming to ground state pluripotency J Yang, AL Van Oosten, TW Theunissen, G Guo, JCR Silva, A Smith Cell stem cell 7 (3), 319-328, 2010 | 270 | 2010 |
| Mitotically stable association of polycomb group proteins eed and enx1 with the inactive x chromosome in trophoblast stem cells W Mak, J Baxter, J Silva, AE Newall, AP Otte, N Brockdorff Current biology 12 (12), 1016-1020, 2002 | 254 | 2002 |
| A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages A Radzisheuskaya, G Le Bin Chia, RL Dos Santos, TW Theunissen, ... Nature cell biology 15 (6), 579-590, 2013 | 233 | 2013 |
| MBD3/NuRD facilitates induction of pluripotency in a context-dependent manner RL Dos Santos, L Tosti, A Radzisheuskaya, IM Caballero, K Kaji, ... Cell stem cell 15 (1), 102-110, 2014 | 210 | 2014 |
| Nanog overcomes reprogramming barriers and induces pluripotency in minimal conditions TW Theunissen, AL Van Oosten, G Castelo-Branco, J Hall, A Smith, ... Current Biology 21 (1), 65-71, 2011 | 197 | 2011 |
| Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming M Fidalgo, F Faiola, CF Pereira, J Ding, A Saunders, J Gingold, ... Proceedings of the National Academy of Sciences, 2012 | 148 | 2012 |
| Do all roads lead to Oct4? The emerging concepts of induced pluripotency A Radzisheuskaya, JCR Silva Trends in cell biology 24 (5), 275-284, 2014 | 141 | 2014 |
| JAK/STAT3 signalling is sufficient and dominant over antagonistic cues for the establishment of naive pluripotency AL Van Oosten, Y Costa, A Smith, JCR Silva Nature communications 3 (1), 817, 2012 | 130 | 2012 |
Thorold W. TheunissenAssociate Professor of Developmental Biology at Washington University in St. LouisVerifierad e-postadress på wustl.edu