Cellular and molecular mechanisms of metformin: an overview B Viollet, B Guigas, NS Garcia, J Leclerc, M Foretz, F Andreelli Clinical science 122 (6), 253-270, 2012 | 2217 | 2012 |
Metformin: from mechanisms of action to therapies M Foretz, B Guigas, L Bertrand, M Pollak, B Viollet Cell metabolism 20 (6), 953-966, 2014 | 1514 | 2014 |
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state M Foretz, S Hébrard, J Leclerc, E Zarrinpashneh, M Soty, G Mithieux, ... The Journal of clinical investigation 120 (7), 2355-2369, 2010 | 1494 | 2010 |
Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP RA Miller, Q Chu, J Xie, M Foretz, B Viollet, MJ Birnbaum Nature 494 (7436), 256-260, 2013 | 1067 | 2013 |
Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes M Foretz, C Guichard, P Ferré, F Foufelle Proceedings of the National Academy of Sciences 96 (22), 12737-12742, 1999 | 925 | 1999 |
AMP-activated protein kinase–deficient mice are resistant to the metabolic effects of resveratrol JH Um, SJ Park, H Kang, S Yang, M Foretz, MW McBurney, MK Kim, ... Diabetes 59 (3), 554-563, 2010 | 757 | 2010 |
Anti-inflammatory effects of metformin irrespective of diabetes status AR Cameron, VL Morrison, D Levin, M Mohan, C Forteath, C Beall, ... Circulation research 119 (5), 652-665, 2016 | 711 | 2016 |
Mitochondrial fission and remodelling contributes to muscle atrophy V Romanello, E Guadagnin, L Gomes, I Roder, C Sandri, Y Petersen, ... The EMBO journal 29 (10), 1774-1785, 2010 | 694 | 2010 |
ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose M Foretz, C Pacot, I Dugail, P Lemarchand, C Guichard, X Le Lièpvre, ... Molecular and cellular biology 19 (5), 3760-3768, 1999 | 671 | 1999 |
Activation of AMP‐activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders B Viollet, M Foretz, B Guigas, S Horman, R Dentin, L Bertrand, L Hue, ... The Journal of physiology 574 (1), 41-53, 2006 | 659 | 2006 |
Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus M Foretz, B Guigas, B Viollet Nature Reviews Endocrinology 15 (10), 569-589, 2019 | 602 | 2019 |
AMP‐activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives B Viollet, B Guigas, J Leclerc, S Hébrard, L Lantier, R Mounier, F Andreelli, ... Acta physiologica 196 (1), 81-98, 2009 | 582 | 2009 |
5′-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments KR Laderoute, K Amin, JM Calaoagan, M Knapp, T Le, J Orduna, ... Molecular and cellular biology 26 (14), 5336-5347, 2006 | 524 | 2006 |
Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver M Foretz, N Ancellin, F Andreelli, Y Saintillan, P Grondin, A Kahn, ... Diabetes 54 (5), 1331-1339, 2005 | 519 | 2005 |
Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase O Göransson, A McBride, SA Hawley, FA Ross, N Shpiro, M Foretz, ... Journal of Biological Chemistry 282 (45), 32549-32560, 2007 | 518 | 2007 |
AMPK inhibition in health and disease B Viollet, S Horman, J Leclerc, L Lantier, M Foretz, M Billaud, S Giri, ... Critical reviews in biochemistry and molecular biology 45 (4), 276-295, 2010 | 496 | 2010 |
Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of … A Woods, D Azzout-Marniche, M Foretz, SC Stein, P Lemarchand, P Ferré, ... Molecular and cellular biology 20 (18), 6704-6711, 2000 | 492 | 2000 |
AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration R Mounier, M Théret, L Arnold, S Cuvellier, L Bultot, O Göransson, N Sanz, ... Cell metabolism 18 (2), 251-264, 2013 | 486 | 2013 |
AMPK in skeletal muscle function and metabolism R Kjøbsted, JR Hingst, J Fentz, M Foretz, MN Sanz, C Pehmøller, M Shum, ... The FASEB journal 32 (4), 1741, 2018 | 464 | 2018 |
Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice S Troy, M Soty, L Ribeiro, L Laval, S Migrenne, X Fioramonti, B Pillot, ... Cell metabolism 8 (3), 201-211, 2008 | 417 | 2008 |