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Oliver Mühlemann
Oliver Mühlemann
Professor of Biochemistry
Verifierad e-postadress på unibe.ch - Startsida
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SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation
K Schubert, ED Karousis, A Jomaa, A Scaiola, B Echeverria, LA Gurzeler, ...
Nature structural & molecular biology 27 (10), 959-966, 2020
5972020
SMG6 promotes endonucleolytic cleavage of nonsense mRNA in human cells
AB Eberle, S Lykke-Andersen, O Mühlemann, TH Jensen
Nature structural & molecular biology 16 (1), 49-55, 2009
4822009
Nonsense-mediated mRNA decay—mechanisms of substrate mRNA recognition and degradation in mammalian cells
C Schweingruber, SC Rufener, D Zünd, A Yamashita, O Mühlemann
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1829 (6-7 …, 2013
4042013
Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors
P Nicholson, H Yepiskoposyan, S Metze, R Zamudio Orozco, ...
Cellular and molecular life sciences 67, 677-700, 2010
4012010
Inhibition by SR proteins of splicing of a regulated adenovirus pre-mRNA
A Kanopka, O Mühlemann, G Akusjärvi
Nature 381 (6582), 535-538, 1996
3731996
Posttranscriptional gene regulation by spatial rearrangement of the 3′ untranslated region
AB Eberle, L Stalder, H Mathys, RZ Orozco, O Mühlemann
PLoS biology 6 (4), e92, 2008
3292008
EJC-independent degradation of nonsense immunoglobulin-μ mRNA depends on 3′ UTR length
M Bühler, S Steiner, F Mohn, A Paillusson, O Mühlemann
Nature structural & molecular biology 13 (5), 462-464, 2006
3222006
Autoregulation of the nonsense-mediated mRNA decay pathway in human cells
H Yepiskoposyan, F Aeschimann, D Nilsson, M Okoniewski, ...
Rna 17 (12), 2108-2118, 2011
2882011
Regulation of adenovirus alternative RNA splicing by dephosphorylation of SR proteins
A Kanopka, O Mühlemann, S Petersen-Mahrt, C Estmer, C Öhrmalm, ...
Nature 393 (6681), 185-187, 1998
2831998
Nonsense‐mediated mRNA decay: novel mechanistic insights and biological impact
ED Karousis, S Nasif, O Mühlemann
Wiley Interdisciplinary Reviews: RNA 7 (5), 661-682, 2016
2112016
Nonsense-mediated mRNA decay begins where translation ends
ED Karousis, O Mühlemann
Cold Spring Harbor perspectives in biology 11 (2), a032862, 2019
2102019
Transcriptome-wide identification of NMD-targeted human mRNAs reveals extensive redundancy between SMG6-and SMG7-mediated degradation pathways
M Colombo, ED Karousis, J Bourquin, R Bruggmann, O Mühlemann
Rna 23 (2), 189-201, 2017
2042017
The host nonsense-mediated mRNA decay pathway restricts mammalian RNA virus replication
G Balistreri, P Horvath, C Schweingruber, D Zünd, G McInerney, A Merits, ...
Cell host & microbe 16 (3), 403-411, 2014
1982014
The solution structure of FUS bound to RNA reveals a bipartite mode of RNA recognition with both sequence and shape specificity
FE Loughlin, PJ Lukavsky, T Kazeeva, S Reber, EM Hock, M Colombo, ...
Molecular cell 73 (3), 490-504. e6, 2019
1952019
Translation-dependent displacement of UPF1 from coding sequences causes its enrichment in 3′ UTRs
D Zünd, AR Gruber, M Zavolan, O Mühlemann
Nature structural & molecular biology 20 (8), 936-943, 2013
1952013
The meaning of nonsense
L Stalder, O Mühlemann
Trends in cell biology 18 (7), 315-321, 2008
1922008
Beyond quality control: The role of nonsense-mediated mRNA decay (NMD) in regulating gene expression
S Nasif, L Contu, O Mühlemann
Seminars in cell & developmental biology 75, 78-87, 2018
1732018
Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways
S Metze, VA Herzog, MD Ruepp, O Mühlemann
Rna 19 (10), 1432-1448, 2013
1612013
Recognition and elimination of nonsense mRNA
O Mühlemann, AB Eberle, L Stalder, RZ Orozco
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1779 (9), 538-549, 2008
1562008
Cutting the nonsense: the degradation of PTC-containing mRNAs
P Nicholson, O Mühlemann
Biochemical Society Transactions 38 (6), 1615-1620, 2010
1452010
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Artiklar 1–20