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Biomolecular condensates: organizers of cellular biochemistry

SF Banani, HO Lee, AA Hyman, MK Rosen

Nature reviews Molecular cell biology 18 (5), 285-298, 2017

Krav: Howard Hughes Medical Institute

Phase transitions in the assembly of multivalent signalling proteins

P Li, S Banjade, HC Cheng, S Kim, B Chen, L Guo, M Llaguno, ...

Nature 483 (7389), 336-340, 2012

Krav: US National Institutes of Health, Howard Hughes Medical Institute

Formation and maturation of phase-separated liquid droplets by RNA-binding proteins

Y Lin, DSW Protter, MK Rosen, R Parker

Molecular cell 60 (2), 208-219, 2015

Krav: US National Institutes of Health, Howard Hughes Medical Institute

Compositional control of phase-separated cellular bodies

SF Banani, AM Rice, WB Peeples, Y Lin, S Jain, R Parker, MK Rosen

Cell 166 (3), 651-663, 2016

Krav: US National Science Foundation, US National Institutes of Health, Howard …

[HTML] science.org

Phase separation of signaling molecules promotes T cell receptor signal transduction

X Su, JA Ditlev, E Hui, W Xing, S Banjade, J Okrut, DS King, J Taunton, ...

Science 352 (6285), 595-599, 2016

Krav: Swiss National Science Foundation, US National Institutes of Health, Howard …

Organization of chromatin by intrinsic and regulated phase separation

BA Gibson, LK Doolittle, MWG Schneider, LE Jensen, N Gamarra, ...

Cell 179 (2), 470-484. e21, 2019

Krav: US National Institutes of Health, Howard Hughes Medical Institute, Austrian …

Sequence determinants of intracellular phase separation by complex coacervation of a disordered protein

CW Pak, M Kosno, AS Holehouse, SB Padrick, A Mittal, R Ali, AA Yunus, ...

Molecular cell 63 (1), 72-85, 2016

Krav: US National Institutes of Health, Howard Hughes Medical Institute

A framework for understanding the functions of biomolecular condensates across scales

AS Lyon, WB Peeples, MK Rosen

Nature Reviews Molecular Cell Biology 22 (3), 215-235, 2021

Krav: US National Institutes of Health, Howard Hughes Medical Institute

[HTML] elifesciences.org

Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins

TS Harmon, AS Holehouse, MK Rosen, RV Pappu

elife 6, e30294, 2017

Krav: US National Science Foundation, US National Institutes of Health, Howard …

[HTML] elifesciences.org

Phase transitions of multivalent proteins can promote clustering of membrane receptors

S Banjade, MK Rosen

elife 3, e04123, 2014

Krav: US National Institutes of Health, Howard Hughes Medical Institute

Structure and control of the actin regulatory WAVE complex

Z Chen, D Borek, SB Padrick, TS Gomez, Z Metlagel, AM Ismail, ...

Nature 468 (7323), 533-538, 2010

Krav: US National Institutes of Health, Howard Hughes Medical Institute

[PDF] science.org

Stoichiometry controls activity of phase-separated clusters of actin signaling proteins

LB Case, X Zhang, JA Ditlev, MK Rosen

Science 363 (6431), 1093-1097, 2019

Krav: US National Institutes of Health, Howard Hughes Medical Institute, Damon …

[HTML] jbc.org

Intrinsically disordered sequences enable modulation of protein phase separation through distributed tyrosine motifs

Y Lin, SL Currie, MK Rosen

Journal of Biological Chemistry 292 (46), 19110-19120, 2017

Krav: US National Institutes of Health, Howard Hughes Medical Institute

[HTML] sciencedirect.com

Who's in and who's out—compositional control of biomolecular condensates

JA Ditlev, LB Case, MK Rosen

Journal of molecular biology 430 (23), 4666-4684, 2018

Krav: US National Institutes of Health, Howard Hughes Medical Institute, Damon …

Intrinsically disordered regions can contribute promiscuous interactions to RNP granule assembly

DSW Protter, BS Rao, B Van Treeck, Y Lin, L Mizoue, MK Rosen, ...

Cell reports 22 (6), 1401-1412, 2018

Krav: US National Institutes of Health, Howard Hughes Medical Institute

Nuclear import receptor inhibits phase separation of FUS through binding to multiple sites

T Yoshizawa, R Ali, J Jiou, HYJ Fung, KA Burke, SJ Kim, Y Lin, ...

Cell 173 (3), 693-705. e22, 2018

Krav: US Department of Energy, US National Institutes of Health, Howard Hughes …

The WAVE regulatory complex links diverse receptors to the actin cytoskeleton

B Chen, K Brinkmann, Z Chen, CW Pak, Y Liao, S Shi, L Henry, ...

Cell 156 (1), 195-207, 2014

Krav: US National Institutes of Health, Howard Hughes Medical Institute, German …

Physical mechanisms of signal integration by WASP family proteins

SB Padrick, MK Rosen

Annual review of biochemistry 79 (1), 707-735, 2010

Krav: US National Institutes of Health, Howard Hughes Medical Institute

Regulation of WASH-dependent actin polymerization and protein trafficking by ubiquitination

YH Hao, JM Doyle, S Ramanathan, TS Gomez, D Jia, M Xu, ZJ Chen, ...

Cell 152 (5), 1051-1064, 2013

Krav: US National Institutes of Health, Howard Hughes Medical Institute