Apolipoprotein E (APOE) genotype-associated disease risks: a phenome-wide, registry-based, case-control study utilising the UK Biobank AL Lumsden, A Mulugeta, A Zhou, E Hyppönen EBioMedicine 59, 2020 | 216 | 2020 |
Huntingtin-deficient zebrafish exhibit defects in iron utilization and development AL Lumsden, TL Henshall, S Dayan, MT Lardelli, RI Richards Human molecular genetics 16 (16), 1905-1920, 2007 | 192 | 2007 |
Mutations of the gene encoding the transmembrane transporter protein ABC-C6 cause pseudoxanthoma elasticum B Struk, L Cai, S Zäch, W Ji, J Chung, A Lumsden, M Stumm, M Huber, ... Journal of molecular medicine 78, 282-286, 2000 | 165 | 2000 |
Molecular genetics of pseudoxanthoma elasticum: type and frequency of mutations in ABCC6 S Miksch, A Lumsden, UP Guenther, D Foernzler, S Christen‐Zäch, ... Human mutation 26 (3), 235-248, 2005 | 124 | 2005 |
Augmented capacity for peripheral serotonin release in human obesity RL Young, AL Lumsden, AM Martin, G Schober, N Pezos, SS Thazhath, ... International Journal of Obesity 42 (11), 1880-1889, 2018 | 92 | 2018 |
Regional differences in nutrient‐induced secretion of gut serotonin AM Martin, AL Lumsden, RL Young, CF Jessup, NJ Spencer, DJ Keating Physiological Reports 5 (6), e13199, 2017 | 84 | 2017 |
The nutrient‐sensing repertoires of mouse enterochromaffin cells differ between duodenum and colon AM Martin, AL Lumsden, RL Young, CF Jessup, NJ Spencer, DJ Keating Neurogastroenterology & Motility 29 (6), e13046, 2017 | 82 | 2017 |
Activation of pruritogenic TGR5, MrgprA3, and MrgprC11 on colon-innervating afferents induces visceral hypersensitivity J Castro, AM Harrington, TM Lieu, S Garcia-Caraballo, J Maddern, ... JCI insight 4 (20), e131712, 2019 | 73 | 2019 |
Selective neuronal requirement for huntingtin in the developing zebrafish TL Henshall, B Tucker, AL Lumsden, S Nornes, MT Lardelli, RI Richards Human molecular genetics 18 (24), 4830-4842, 2009 | 67 | 2009 |
Deficiency of Huntingtin Has Pleiotropic Effects in the Social Amoeba Dictyostelium discoideum MA Myre, AL Lumsden, MN Thompson, W Wasco, ME MacDonald, ... PLoS genetics 7 (4), e1002052, 2011 | 66 | 2011 |
Serotonin-secreting enteroendocrine cells respond via diverse mechanisms to acute and chronic changes in glucose availability L Zelkas, R Raghupathi, AL Lumsden, AM Martin, E Sun, NJ Spencer, ... Nutrition & metabolism 12, 1-9, 2015 | 60 | 2015 |
A novel Q378X mutation exists in the transmembrane transporter protein ABCC6 and its pseudogene: implications for mutation analysis in pseudoxanthoma … L Cai, A Lumsden, UP Guenther, SA Neldner, S Zäch, H Knoblauch, ... Journal of molecular medicine 79, 536-546, 2001 | 56 | 2001 |
Gut serotonin is a regulator of obesity and metabolism RL Young, AL Lumsden, DJ Keating Gastroenterology 149 (1), 253-255, 2015 | 50 | 2015 |
Dysregulation of neuronal iron homeostasis as an alternative unifying effect of mutations causing familial Alzheimer’s disease AL Lumsden, JT Rogers, S Majd, M Newman, GT Sutherland, G Verdile, ... Frontiers in neuroscience 12, 533, 2018 | 44 | 2018 |
Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2 N Hin, M Newman, J Kaslin, AM Douek, A Lumsden, SHM Nik, Y Dong, ... PloS one 15 (1), e0227258, 2020 | 28 | 2020 |
Huntingtin‐associated protein‐1 is a synapsin I‐binding protein regulating synaptic vesicle exocytosis and synapsin I trafficking KD Mackenzie, AL Lumsden, F Guo, MD Duffield, T Chataway, Y Lim, ... Journal of neurochemistry 138 (5), 710-721, 2016 | 28 | 2016 |
Sugar responses of human enterochromaffin cells depend on gut region, sex, and body mass AL Lumsden, AM Martin, EW Sun, G Schober, NJ Isaacs, N Pezos, ... Nutrients 11 (2), 234, 2019 | 27 | 2019 |
Olorinab (APD371), a peripherally acting, highly selective, full agonist of the cannabinoid receptor 2, reduces colitis-induced acute and chronic visceral hypersensitivity in … J Castro, S Garcia-Caraballo, J Maddern, G Schober, A Lumsden, ... Pain 163 (1), e72-e86, 2022 | 26 | 2022 |
Fusion pore size limits 5‐HT release from single enterochromaffin cell vesicles R Raghupathi, CF Jessup, AL Lumsden, DJ Keating Journal of cellular physiology 231 (7), 1593-1600, 2016 | 25 | 2016 |
Relationship between serum 25 (OH) D and depression: causal evidence from a bi-directional Mendelian randomization study A Mulugeta, A Lumsden, E Hyppönen Nutrients 13 (1), 109, 2020 | 24 | 2020 |