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Max W Shen
Max W Shen
Genentech
Verifierad e-postadress på mit.edu - Startsida
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Predictable and precise template-free CRISPR editing of pathogenic variants
MW Shen, M Arbab, JY Hsu, D Worstell, SJ Culbertson, O Krabbe, ...
Nature 563 (7733), 646-651, 2018
5772018
plasmidSPAdes: assembling plasmids from whole genome sequencing data
PAP Dmitry Antipov, Nolan Hartwick, Max W Shen, Mikahil Raiko, Alla Lapidus
Bioinformatics 32 (22), 3380-3387, 2016
5492016
Continuous evolution of SpCas9 variants compatible with non-G PAMs
SM Miller, T Wang, PB Randolph, M Arbab, MW Shen, TP Huang, ...
Nature biotechnology 38 (4), 471-481, 2020
3492020
Assembly of long error-prone reads using de Bruijn graphs
Y Lin, J Yuan, M Kolmogorov, MW Shen, M Chaisson, PA Pevzner
Proceedings of the National Academy of Sciences 113 (52), E8396-E8405, 2016
3472016
Cis and trans determinants of epigenetic silencing by Polycomb repressive complex 2 in Arabidopsis
J Xiao, R Jin, X Yu, M Shen, JD Wagner, A Pai, C Song, M Zhuang, ...
Nature genetics 49 (10), 1546-1552, 2017
2542017
Determinants of Base Editing Outcomes from Target Library Analysis and Machine Learning
Max W. Shen*, Mandana Arbab*, Beverly Mok, Christopher Wilson, Żaneta ...
Cell, 2020
2512020
Efficient C• G-to-G• C base editors developed using CRISPRi screens, target-library analysis, and machine learning
LW Koblan, M Arbab, MW Shen, JA Hussmann, AV Anzalone, JL Doman, ...
Nature biotechnology 39 (11), 1414-1425, 2021
1882021
PrimeDesign software for rapid and simplified design of prime editing guide RNAs
JY Hsu, J Grünewald, R Szalay, J Shih, AV Anzalone, KC Lam, MW Shen, ...
Nature Communications 12 (1), 1034, 2021
1682021
Base editing rescue of spinal muscular atrophy in cells and in mice
M Arbab, Z Matuszek, KM Kray, A Du, GA Newby, AJ Blatnik, A Raguram, ...
Science 380 (6642), eadg6518, 2023
792023
MEG source imaging method using fast L1 minimum-norm and its applications to signals with brain noise and human resting-state source amplitude images
MX Huang, CW Huang, A Robb, AM Angeles, SL Nichols, DG Baker, ...
Neuroimage 84, 585-604, 2014
712014
Towards understanding and improving gflownet training
MW Shen, E Bengio, E Hajiramezanali, A Loukas, K Cho, T Biancalani
International conference on machine learning, 30956-30975, 2023
512023
Peptide fusion improves prime editing efficiency
M Velimirovic, LC Zanetti, MW Shen, JD Fife, L Lin, M Cha, E Akinci, ...
Nature Communications 13 (1), 3512, 2022
482022
Meta-analysis of point-of-care lung ultrasonography versus chest radiography in adults with symptoms of acute decompensated heart failure
L Chiu, MP Jairam, R Chow, N Chiu, M Shen, A Alhassan, CH Lo, A Chen, ...
The American journal of cardiology 174, 89-95, 2022
432022
Trust in AI: Interpretability is not necessary or sufficient, while black-box interaction is necessary and sufficient
MW Shen
arXiv preprint arXiv:2202.05302, 2022
252022
Stab: Self-supervised learning for tabular data
E Hajiramezanali, NL Diamant, G Scalia, MW Shen
NeurIPS 2022 first table representation workshop, 2022
192022
Small molecule inhibition of ATM kinase increases CRISPR-Cas9 1-bp insertion frequency
HC Bermudez-Cabrera, S Culbertson, S Barkal, B Holmes, MW Shen, ...
Nature communications 12 (1), 5111, 2021
182021
Systems and methods for predicting repair outcomes in genetic engineering
MW Shen, JYT HSU, M Arbab, DK Gifford, DR Liu, RI Sherwood
162020
Comprehensive Mapping of Key Regulatory Networks that Drive Oncogene Expression
L Lin, B Holmes, MW Shen, D Kammeron, N Geijsen, DK Gifford, ...
Cell Reports 33 (8), 2020
142020
Base editor predictive algorithm and method of use
DR Liu, M Arbab, MW Shen, C Cassa
US Patent App. 17/797,697, 2023
122023
Generating experimentally unrelated target molecule-binding highly functionalized nucleic-acid polymers using machine learning
JC Chen, JP Chen, MW Shen, M Wornow, M Bae, WH Yeh, A Hsu, DR Liu
Nature Communications 13 (1), 4541, 2022
122022
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Artiklar 1–20