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Tuhin K. Guha
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The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution
O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ...
Cell 181 (2), 236-249, 2020
4642020
Single-cell analyses define a continuum of cell state and composition changes in the malignant transformation of polyps to colorectal cancer
WR Becker, SA Nevins, DC Chen, R Chiu, AM Horning, TK Guha, ...
Nature genetics 54 (7), 985-995, 2022
1722022
Programmable genome editing tools and their regulation for efficient genome engineering
TK Guha, A Wai, G Hausner
Computational and structural biotechnology journal 15, 146-160, 2017
1622017
MITI minimum information guidelines for highly multiplexed tissue images
D Schapiro, C Yapp, A Sokolov, SM Reynolds, YA Chen, D Sudar, Y Xie, ...
Nature methods 19 (3), 262-267, 2022
562022
Applications of alternative nucleases in the age of CRISPR/Cas9
TK Guha, DR Edgell
International journal of molecular sciences 18 (12), 2565, 2017
512017
The intron landscape of the mtDNA cytb gene among the Ascomycota: introns and intron-encoded open reading frames
TK Guha, A Wai, ST Mullineux, G Hausner
Mitochondrial DNA Part A 29 (7), 1015-1024, 2018
312018
Production of endoglucanase and xylanase using food waste by solid-state fermentation
M Tian, A Wai, TK Guha, G Hausner, Q Yuan
Waste and Biomass Valorization 9, 2391-2398, 2018
232018
A homing endonuclease with a switch: characterization of a twintron encoded homing endonuclease
TK Guha, G Hausner
Fungal Genetics and Biology 65, 57-68, 2014
172014
Plasmid-mediated gene therapy in mouse models of limb girdle muscular dystrophy
TK Guha, C Pichavant, MP Calos
Molecular Therapy Methods & Clinical Development 15, 294-304, 2019
132019
Nucleofection of phiC31 integrase protein mediates sequence-specific genomic integration in human cells
TK Guha, MP Calos
Journal of Molecular Biology 432 (13), 3950-3955, 2020
122020
Using Group II Introns for Attenuating the In Vitro and In Vivo Expression of a Homing Endonuclease
GH Tuhin Kumar Guha
PLoS ONE 11 (2), 2016
92016
Simultaneous profiling of host expression and microbial abundance by spatial metatranscriptome sequencing
L Lyu, X Li, R Feng, X Zhou, TK Guha, X Yu, GQ Chen, Y Yao, B Su, ...
Genome Research 33 (3), 401-411, 2023
72023
PCR-based bioprospecting for homing endonucleases in fungal mitochondrial rRNA genes
M Hafez, TK Guha, C Shen, J Sethuraman, G Hausner
Homing Endonucleases: Methods and Protocols, 37-53, 2014
72014
Insertion of group II intron-based ribozyme switches into homing endonuclease genes
TK Guha, G Hausner
In Vitro Mutagenesis: Methods and Protocols, 135-152, 2017
42017
I-OmiI and I-OmiII: Two intron-encoded homing endonucleases within the Ophiostoma minus rns gene
M Hafez, TK Guha, G Hausner
Fungal Biology 118 (8), 721-731, 2014
42014
Multiomic analysis of familial adenomatous polyposis reveals molecular pathways associated with early tumorigenesis
ED Esplin, C Hanson, S Wu, AM Horning, N Barapour, SA Nevins, L Jiang, ...
Nature Cancer 5 (11), 1737-1753, 2024
22024
Three new active members of the I-OnuI family of homing endonucleases
IM Bilto, TK Guha, A Wai, G Hausner
Canadian Journal of Microbiology 63 (8), 671-681, 2017
22017
The polyclonal path to malignant transformation in familial adenomatous polyposis
RO Schenck, A Khan, A Horning, ED Esplin, E Monte, S Wu, C Hanson, ...
Cancer Research 83 (7_Supplement), 3497-3497, 2023
12023
A Multiomics, Spatiotemporal, and Single Cell Atlas for Mapping Cell-Type-Specific Dysregulation at the Maternal-Fetal Interface
C Wang, Y Zhou, YJ Wang, TK Guha, Z Luo, TI McIntyre, ME Schwab, ...
bioRxiv, 2024.01. 18.576324, 2024
2024
Single-cell spatial mapping reveals alteration of cell type composition and tissue microenvironment during early colorectal cancer formation
TK Guha, ED Esplin, AM Horning, R Chiu, K Paul, AK Weimer, WR Becker, ...
bioRxiv, 2024.11. 20.622725, 2024
2024
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Artiklar 1–20