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Daniel J Cook
Daniel J Cook
Scientist, SimBioSys
Verifierad e-postadress på simbiosys.com
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An atlas of human metabolism
JL Robinson, P Kocabaş, H Wang, PE Cholley, D Cook, A Nilsson, ...
Science signaling 13 (624), eaaz1482, 2020
3512020
Genome‐scale metabolic models applied to human health and disease
DJ Cook, J Nielsen
Wiley Interdisciplinary Reviews: Systems Biology and Medicine 9 (6), e1393, 2017
562017
An agent-based modeling framework for evaluating hypotheses on risks for developing autism: Effects of the gut microbial environment
B Weston, B Fogal, D Cook, P Dhurjati
Medical Hypotheses 84 (4), 395-401, 2015
392015
Metastatic triple negative breast cancer adapts its metabolism to destination tissues while retaining key metabolic signatures
F Roshanzamir, JL Robinson, D Cook, MH Karimi-Jafari, J Nielsen
Proceedings of the National Academy of Sciences 119 (35), e2205456119, 2022
382022
Model-based hypothesis of gut microbe populations and gut/brain barrier permeabilities in the development of regressive autism
R Downs, J Perna, A Vitelli, D Cook, P Dhurjati
Medical hypotheses 83 (6), 649-655, 2014
352014
Systems analysis of non-parenchymal cell modulation of liver repair across multiple regeneration modes
D Cook, BA Ogunnaike, R Vadigepalli
BMC systems biology 9, 1-24, 2015
342015
Maximum recommended dosage of lithium for pregnant women based on a PBPK model for lithium absorption
S Horton, A Tuerk, D Cook, J Cook, P Dhurjati
Advances in bioinformatics 2012 (1), 352729, 2012
332012
Adiponectin fine‐tuning of liver regeneration dynamics revealed through cellular network modelling
JM Correnti, D Cook, E Aksamitiene, A Swarup, B Ogunnaike, ...
The Journal of Physiology 593 (2), 365-383, 2015
232015
Systems biology investigation of cAMP modulation to increase SMN levels for the treatment of spinal muscular atrophy
SG Mack, DJ Cook, P Dhurjati, MER Butchbach
PLoS One 9 (12), e115473, 2014
152014
Cellular network modeling and single cell gene expression analysis reveals novel hepatic stellate cell phenotypes controlling liver regeneration dynamics
D Cook, S Achanta, JB Hoek, BA Ogunnaike, R Vadigepalli
BMC Systems Biology 12, 1-29, 2018
132018
A novel, dynamic pattern-based analysis of NF-κB binding during the priming phase of liver regeneration reveals switch-like functional regulation of target genes
DJ Cook, B Patra, L Kuttippurathu, JB Hoek, R Vadigepalli
Frontiers in physiology 6, 189, 2015
102015
Molecular natural history of breast cancer: Leveraging transcriptomics to predict breast cancer progression and aggressiveness
DJ Cook, J Kallus, R Jörnsten, J Nielsen
Cancer Medicine 9 (10), 3551-3562, 2020
92020
Pattern analysis uncovers a chronic ethanol-induced disruption of the switch-like dynamics of C/EBP-β and C/EBP-α genome-wide binding during liver regeneration
L Kuttippurathu, B Patra, D Cook, JB Hoek, R Vadigepalli
Physiological Genomics 49 (1), 11-26, 2017
62017
Computational Modeling as an Approach to Study the Cellular and Molecular Regulatory Networks Driving Liver Regeneration
D Cook, R Vadigepalli
Liver Regeneration, 185-198, 2015
52015
Next generation immuno-oncology tumor profiling using a rapid, non-invasive, computational biophysics biomarker in early-stage breast cancer
D Cook, M Biancalana, N Liadis, D Lopez Ramos, Y Zhang, S Patel, ...
Frontiers in Artificial Intelligence 6, 1153083, 2023
32023
Elucidating the Mechanisms of Dynamic and Robust Control of the Liver Homeostatic Renewal Process: Cell Network Modeling and Analysis
D Cook, A Manchel, BA Ogunnaike, R Vadigepalli
Industrial & Engineering Chemistry Research 62 (5), 2275-2287, 2023
22023
Computational speed-up of large-scale, single-cell model simulations via a fully integrated SBML-based format
A Mutsuddy, C Erdem, JR Huggins, M Salim, D Cook, N Hobbs, FA Feltus, ...
Bioinformatics Advances 3 (1), vbad039, 2023
22023
Accurate prediction of tumor growth and doubling times for triple negative breast cancer (TNBC) allows for patient-specific assessment of tumor aggressiveness
J Whitman, D Cook, S Patel, L Munn, JA Cole, SimBioSys Team
Cancer Research 82 (12_Supplement), 2721-2721, 2022
12022
45P Spatially-resolved single-cell HER2 tumor heterogeneity captured by biophysical modeling
D Cook, N Hobbs, D Lopez-Ramos, J Cole, S Patel
Annals of Oncology 33, S142, 2022
12022
Abstract P1-08-31: Simbiosys tumorscope: Biophysical modeling of patient-specific response to chemotherapy
JA Cole Jr, JR Peterson, TM Earnest, MJ Hallock, DJ Cook, E Braun, ...
Cancer Research 82 (4_Supplement), P1-08-31-P1-08-31, 2022
12022
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Artiklar 1–20