| Amyloid beta: structure, biology and structure-based therapeutic development G Chen, T Xu, Y Yan, Y Zhou, Y Jiang, K Melcher, HE Xu Acta pharmacologica sinica 38 (9), 1205-1235, 2017 | 2069 | 2017 |
| Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir W Yin, C Mao, X Luan, DD Shen, Q Shen, H Su, X Wang, F Zhou, W Zhao, ... Science 368 (6498), 1499-1504, 2020 | 1276 | 2020 |
| Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser Y Kang, XE Zhou, X Gao, Y He, W Liu, A Ishchenko, A Barty, TA White, ... Nature 523 (7562), 561-567, 2015 | 869 | 2015 |
| Structural features for functional selectivity at serotonin receptors D Wacker, C Wang, V Katritch, GW Han, XP Huang, E Vardy, JD McCorvy, ... Science 340 (6132), 615-619, 2013 | 822 | 2013 |
| Structural basis for molecular recognition at serotonin receptors C Wang, Y Jiang, J Ma, H Wu, D Wacker, V Katritch, GW Han, W Liu, ... Science 340 (6132), 610-614, 2013 | 616 | 2013 |
| G protein-coupled receptors: structure-and function-based drug discovery D Yang, Q Zhou, V Labroska, S Qin, S Darbalaei, Y Wu, E Yuliantie, L Xie, ... Signal transduction and targeted therapy 6 (1), 7, 2021 | 522 | 2021 |
| Cryo-EM structure of human rhodopsin bound to an inhibitory G protein Y Kang, O Kuybeda, PW de Waal, S Mukherjee, N Van Eps, P Dutka, ... Nature 558 (7711), 553-558, 2018 | 276 | 2018 |
| Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody W Yin, Y Xu, P Xu, X Cao, C Wu, C Gu, X He, X Wang, S Huang, Q Yuan, ... Science 375 (6584), 1048-1053, 2022 | 267 | 2022 |
| EZH2: biology, disease, and structure-based drug discovery J Tan, Y Yan, X Wang, Y Jiang, HE Xu Acta Pharmacologica Sinica 35 (2), 161-174, 2014 | 261 | 2014 |
| Structure and dynamics of the active human parathyroid hormone receptor-1 LH Zhao, S Ma, I Sutkeviciute, DD Shen, XE Zhou, PW de Waal, CY Li, ... Science 364 (6436), 148-153, 2019 | 216 | 2019 |
| Structural insights into the lipid and ligand regulation of serotonin receptors P Xu, S Huang, H Zhang, C Mao, XE Zhou, X Cheng, IA Simon, DD Shen, ... Nature 592 (7854), 469-473, 2021 | 214 | 2021 |
| A complex structure of arrestin-2 bound to a G protein-coupled receptor W Yin, Z Li, M Jin, YL Yin, PW De Waal, K Pal, Y Yin, X Gao, Y He, J Gao, ... Cell research 29 (12), 971-983, 2019 | 207 | 2019 |
| Structural insights into the human D1 and D2 dopamine receptor signaling complexes Y Zhuang, P Xu, C Mao, L Wang, B Krumm, XE Zhou, S Huang, H Liu, ... Cell 184 (4), 931-942. e18, 2021 | 201 | 2021 |
| Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-ligase signaling effector DWARF3 LH Zhao, XE Zhou, W Yi, Z Wu, Y Liu, Y Kang, L Hou, PW De Waal, S Li, ... Cell research 25 (11), 1219-1236, 2015 | 188 | 2015 |
| RNA-dependent RNA polymerase: Structure, mechanism, and drug discovery for COVID-19 Y Jiang, W Yin, HE Xu Biochemical and biophysical research communications 538, 47-53, 2021 | 185 | 2021 |
| Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy J Duan, D Shen, XE Zhou, P Bi, Q Liu, Y Tan, Y Zhuang, H Zhang, P Xu, ... Nature communications 11 (1), 4121, 2020 | 172 | 2020 |
| Molecular recognition of morphine and fentanyl by the human μ-opioid receptor Cell 185 (23), 4361-4375, 2022 | 163 | 2022 |
| Structural basis for inhibition of the SARS-CoV-2 RNA polymerase by suramin W Yin, X Luan, Z Li, Z Zhou, Q Wang, M Gao, X Wang, F Zhou, J Shi, ... Nature structural & molecular biology 28 (3), 319-325, 2021 | 150 | 2021 |
| A tandem radiative/evaporative cooler for weather-insensitive and high-performance daytime passive cooling J Li, X Wang, D Liang, N Xu, B Zhu, W Li, P Yao, Y Jiang, X Min, Z Huang, ... Science Advances 8 (31), eabq0411, 2022 | 138 | 2022 |
| Structures of the glucocorticoid-bound adhesion receptor GPR97–Go complex YQ Ping, C Mao, P Xiao, RJ Zhao, Y Jiang, Z Yang, WT An, DD Shen, ... Nature 589 (7843), 620-626, 2021 | 137 | 2021 |
H Eric Xu (徐华强), ProfessorShanghai Institute of Materia Medica, CAS; Tsinghua; Duke; UTSW; MIT; VARI/GlaxoWellcome/GSKVerifierad e-postadress på simm.ac.cn