| Unifying the analysis of high-throughput sequencing datasets: characterizing RNA-seq, 16S rRNA gene sequencing and selective growth experiments by compositional data analysis AD Fernandes, JN Reid, JM Macklaim, TA McMurrough, DR Edgell, ... Microbiome 2, 1-13, 2014 | 1096 | 2014 |
| Archaea and the origin(s) of DNA replication proteins DR Edgell, WF Doolittle Cell 89 (7), 995-998, 1997 | 329 | 1997 |
| Barriers to intron promiscuity in bacteria DR Edgell, M Belfort, DA Shub Journal of Bacteriology 182 (19), 5281-5289, 2000 | 175 | 2000 |
| An Expanded Plasmid-Based Genetic Toolbox Enables Cas9 Genome Editing and Stable Maintenance of Synthetic Pathways in Phaeodactylum tricornutum SS Slattery, A Diamond, H Wang, JA Therrien, JT Lant, T Jazey, K Lee, ... ACS synthetic biology 7 (2), 328-338, 2018 | 154 | 2018 |
| Efficient inter-species conjugative transfer of a CRISPR nuclease for targeted bacterial killing TA Hamilton, GM Pellegrino, JA Therrien, DT Ham, PC Bartlett, BJ Karas, ... Nature communications 10 (1), 4544, 2019 | 116 | 2019 |
| Tapping natural reservoirs of homing endonucleases for targeted gene modification R Takeuchi, AR Lambert, ANS Mak, K Jacoby, RJ Dickson, GB Gloor, ... Proceedings of the National Academy of Sciences 108 (32), 13077-13082, 2011 | 116 | 2011 |
| Bacterial group I introns: mobile RNA catalysts G Hausner, M Hafez, DR Edgell Mobile DNA 5, 1-12, 2014 | 110 | 2014 |
| Mobile DNA elements in T4 and related phages DR Edgell, EA Gibb, M Belfort Virology journal 7, 1-15, 2010 | 96 | 2010 |
| FhuD1, a ferric hydroxamate-binding lipoprotein in Staphylococcus aureus: a case of gene duplication and lateral transfer MT Sebulsky, CD Speziali, BH Shilton, DR Edgell, DE Heinrichs Journal of Biological Chemistry 279 (51), 53152-53159, 2004 | 92 | 2004 |
| Learning to live together: mutualism between self-splicing introns and their hosts DR Edgell, VR Chalamcharla, M Belfort BMC biology 9, 1-9, 2011 | 91 | 2011 |
| Repression of branched-chain amino acid synthesis in Staphylococcus aureus is mediated by isoleucine via CodY, and by a leucine-rich attenuator peptide JC Kaiser, AN King, JC Grigg, JR Sheldon, DR Edgell, MEP Murphy, ... PLoS genetics 14 (1), e1007159, 2018 | 90 | 2018 |
| Genes within genes: multiple LAGLIDADG homing endonucleases target the ribosomal protein S3 gene encoded within an rnl group I intron of Ophiostoma and related taxa J Sethuraman, A Majer, NC Friedrich, DR Edgell, G Hausner Molecular biology and evolution 26 (10), 2299-2315, 2009 | 84 | 2009 |
| Gene duplications in evolution of archaeal family B DNA polymerases DR Edgell, HP Klenk, WF Doolittle Journal of bacteriology 179 (8), 2632-2640, 1997 | 83 | 1997 |
| mitoTev‐TALE: a monomeric DNA editing enzyme to reduce mutant mitochondrial DNA levels CV Pereira, SR Bacman, T Arguello, U Zekonyte, SL Williams, DR Edgell, ... EMBO molecular medicine 10 (9), e8084, 2018 | 81 | 2018 |
| Monomeric site-specific nucleases for genome editing BP Kleinstiver, JM Wolfs, T Kolaczyk, AK Roberts, SX Hu, DR Edgell Proceedings of the National Academy of Sciences 109 (21), 8061-8066, 2012 | 72 | 2012 |
| Selfish DNA: homing endonucleases find a home DR Edgell Current Biology 19 (3), R115-R117, 2009 | 69 | 2009 |
| Related homing endonucleases I-BmoI and I-TevI use different strategies to cleave homologous recognition sites DR Edgell, DA Shub Proceedings of the National Academy of Sciences 98 (14), 7898-7903, 2001 | 60 | 2001 |
| High incidence of significant urinary ascorbic acid concentrations in a west coast population—implications for routine urinalysis ML Brigden, D Edgell, M McPherson, A Leadbeater, G Hoag Clinical Chemistry 38 (3), 426-431, 1992 | 58 | 1992 |
| Biasing genome-editing events toward precise length deletions with an RNA-guided TevCas9 dual nuclease JM Wolfs, TA Hamilton, JT Lant, M Laforet, J Zhang, LM Salemi, GB Gloor, ... Proceedings of the National Academy of Sciences 113 (52), 14988-14993, 2016 | 53 | 2016 |
| Intron-encoded homing endonuclease I-TevI also functions as a transcriptional autorepressor DR Edgell, V Derbyshire, PV Roey, S LaBonne, MJ Stanger, Z Li, ... Nature structural & molecular biology 11 (10), 936-944, 2004 | 52 | 2004 |
Greg GloorProfessor and Chair of Biochemistry, University of Western Ontario, Western UniversityVerifierad e-postadress på uwo.ca
